Results 121 to 130 of about 24,846,870 (325)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
The Algebra of Earth Science [PDF]
In this activity, students will graph carbon dioxide levels against temperature change over time and examine the data to look for trends. Another plotting exercise is provided in which they examine the relationship between the retreat of glaciers and sea
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Frontiers in EndocrinologyBackgroundAlthough the national-based policy implemented an initiative program to offer diabetes care management in Thailand, there are limited time trends of evidence to gauge whether the quality of diabetes care in primary care practice is improving ...
Ratanaporn Awiphan +12 more
doaj +1 more source
Analysis of California surface temperature trends based on observations. [PDF]
, 2009 Analysis of California surface temperature based on observations has been conducted using United States Historical Climatology Network (USHCN) stations and Cooperative Weather (COOP) stations throughout California to understand spatial and temporal ...
Kessomkiat, Wittaya
core +1 more source
Maximum and minimum temperatures in the United States: Time trends and persistence
, 2018 We investigate the time trends in the maximum and minimum temperatures in the United States from 1895 to 2017 using techniques that allow for fractional integration in the detrended series.
L. Gil‐Alana
semanticscholar +1 more source
Time Trends and Patterns of Reported Egg Consumption in the U.S. by Sociodemographic Characteristics
Nutrients, 2017 To 1) describe time trends of the percentage of individuals in the U.S that consume eggs, 2) describe time trends of the daily amount of eggs consumed per day, and 3) examine differences in the amount of eggs consumed per day; overall and by gender, age,
Zach Conrad +4 more
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The epidemiology of colorectal cancer in China
Global Health Journal, 2018 Objective: Colorectal cancer (CRC) is one of the most common cancers and the major cause of cancer death in China. The aim of this study was to estimate the burden of CRC in China.Materials and methods: Data from the National Cancer Center (NCC) of China
Rongshou Zheng +8 more
doaj +1 more source