Results 111 to 120 of about 16,183,947 (297)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Optimized Travel Itineraries: Combining Mandatory Visits and Personalized Activities

open access: yesAlgorithms
Tourism refers to the activity of traveling for pleasure, recreation, or leisure purposes. It encompasses a wide range of activities and experiences, from sightseeing to cultural exploration.
Parida Jewpanya   +3 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

City Lights : Windows Collective : Expanded Cinema at the Shenkman Arts Centre

open access: yes, 2016
Event catalog containing synopsis of the projected films of the City Lights : Windows Collective : Expanded Cinema at the Shenkman Arts Centre ...

core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Hack proofing Windows 2000 /

open access: yes, 2001
The complete, authoritative guide to protecting your Windows 2000 Network "Essential reading for your IT security organization."--Deena Joyce, Director of Information Technology and Network Security, Casino Magic Pick up a newspaper or watch the evening ...
Todd, Chad., Johnson, Norris L.
core  

Time Window Characteristics in a Heuristic Algorithm for a Full-Truck Vehicle Routing Heuristic Algorithm in An Intermodal Context

open access: yesJurnal Optimasi Sistem Industri
Intermodal container terminals handle both the pickup and delivery of containers to and from customers, with these transport activities and terminal handling comprising a significant portion of intermodal transport costs.
Wisute Ongcunaruk   +2 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

EVOLUTIONARY ALGORITHMS FOR CAPACITATED ARC ROUTING PROBLEMS WITH TIME WINDOWS

open access: yes, 2006
The Capacitated Arc Routing Problem (CARP) involves vehicles routing, serving a set of arcs in a network. This NP hard problem is extended to take into account time windows, entailing a new and hard theoretical model in arc routing called the CARPTW ...
Wahiba Ramdane-Cherif   +2 more
core   +1 more source

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