Results 51 to 60 of about 20,663,539 (299)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

A single dose of FSH or hCG during a split-time AI program did not enhance follicular growth or pregnancy per artificial insemination in beef heifers

Journal of Applied Animal Research, 2023
The objective of this study was to evaluate the effect of a low dose of hCG or FSH on follicle growth and pregnancy per artificial insemination (AI) in crossbreed beef heifers subjected to a split-time AI program.
Daniella Heredia, Oscar Alejandro Ojeda-Rojas, Maria C. Londoño, Sergio D. Lasso, Rafael S. Bisinotto, Mario Binelli, Angela M. Gonella-Diaza   +6 more
doaj   +1 more source

Effect of sequence of insemination after simultaneous thawing of multiple semen straws on conception rate to timed AI in suckled multiparous Nelore cows.

Theriogenology, 2012
The objective was to determine the effect of sequence of insemination after simultaneous thawing of multiple 0.5 mL semen straws on conception rate in suckled multiparous Nelore cows. The effect of this thawing procedure on in vitro sperm characteristics
L. Z. Oliveira, R. P. Arruda, A. F. C. D. Andrade, R. Santos, M. E. Beletti, R. Peres, J.P.N. Martins, V. D. Lima   +7 more
semanticscholar   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Economic benefit in repeat breeder cows using intrauterine infusion of penicillin and estrus synchronization followed by timed artificial insemination

Journal of Advanced Veterinary and Animal Research, 2018
Objective: Until recently, management of repeat breeding in cattle remains a major problem to dairy farmers. This study was carried out to improve the fertility in cows, those did not conceive after three or more consecutive services.
Abul Khair, Md. Asaduzzaman, Zinat Sultana, Anup Kumar Taluker, Ziban Chandra Das, Md. Golam Shahi Alam, Mohammed Shamsuddin   +6 more
doaj   +1 more source

Comparative Study of Pregnancy Rate of Dairy Cows Inseminated with Fresh or Frozen-Thawed Semen

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2020
The aim of this study was to investigate conception rates (CR) achieved with artificial insemination of Holstein cows using fresh or frozen insemination doses (ID). The synchronization protocols (Double-Ovsynch, Ovsynch, ReSynch) and pedometers were used
Jan Pytlík, Luděk Stádník, Jaromír Ducháček, Radim Codl   +3 more
doaj   +1 more source

Comparison of plasma concentrations of estradiol-17β and progesterone, and conception in dairy cows with cystic ovarian diseases between Ovsynch and Ovsynch plus CIDR timed AI protocols.

Journal of reproduction and development, 2011
The objectives of this study were 1) to determine the effects of adding a CIDR to the Ovsynch protocol on plasma concentrations of estradiol-17β and progesterone and conception in dairy cows with cystic ovarian diseases and 2) to examine associations ...
N. Kawate, Kensuke Watanabe, K. Uenaka, Masahiro Takahashi, T. Inaba, H. Tamada   +5 more
semanticscholar   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Timed artificial insemination plus heat I: effect of estrus expression scores on pregnancy of cows subjected to progesterone–estradiol-based protocols

Animal, 2019
Expression of estrus near timed artificial insemination (TAI) is associated with greater fertility, and estrus detection could improve TAI fertility or direct TAI management, although accurate estrus detection can be difficult and time-consuming using ...
E. Nogueira, M.R. Silva, J.C.B. Silva, U.P.G. Abreu, N.A. Anache, K.C. Silva, C.J.T. Cardoso, P. Sutovsky, W.B. Rodrigues   +8 more
doaj   +1 more source