Results 81 to 90 of about 168,490,903 (279)
The Prime Minister Gough Whitlam is taken on a tour of the wreckage in Darwin, 1974 [picture] /
Part of collection: Bruce Howard collection of photographs for Herald and Weekly Times, Melbourne, 1955-1995.; Title supplied by photographer, see acquisition file 204/09/00042.; Inscriptions: "Darwin Cyclone Tracy, P.M. Whitlam in leading white car." --
Howard, Bruce, 1936-
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
On a bicycle built for ? [picture] /
Part of collection: Bruce Howard collection of photographs for Herald and Weekly Times, Melbourne, 1955-1994.; Title supplied by photographer, see acquisition file 204/09/00042.; Inscription: "11.11.1981"--On reverse.; Also available in an electronic ...
Howard, Bruce, 1936-
core
EFFECT OF PAUSE TIME OF PULSED CURING LIGHT ON THE TRIBOLOGICAL PERFORMANCE OF COMPOSITE RESIN [PDF]
The objective of the present work is to evaluate the tribological performance of the dental composite resin after curing by continuous and pulsed light modes of different pause time.
A. S. Ali +6 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Ohio school bus minimum construction standards.
Cover title.; " ... The minimum standards covering the construction and equipping of school buses, as recommended by the School Bus Minimum Construction Standards Advisory Committee, adopted by the State Board of Education and filed with the Secretary of
core
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The impact of minimum wages in Mexico and Colombia [PDF]
There are diverging views about how minimum wages affect labor markets in developing countries. Advocates of minimum wages hold that they redistribute resources in a welfare-enhancing way, and can thus reduce poverty, improve productivity, and foster ...
Bell, Linda A.
core
Visible-light-driven photocatalysis is a robust technology for amending the negative effect of pollutants on the environment with a minimum energy use.
La Phan Phuong Ha +5 more
doaj +1 more source

