Results 121 to 130 of about 19,573 (307)

Resistive plate chambers and related detectors

open access: yes, 2006
Contributed and invited papers on issues concerning the performance, the quality and the timing of the Resistive Plate Chamber ...
SANTONICO R.   +2 more
core  

Numerical Proof-of-Concept of Monolithic AC-LGAD Detectors for 4D Particle Tracking

open access: yesSensors
We present the numerical proof of a new sensor concept, based on the Resistive AC-Coupled Silicon Detectors (RSDs) paradigm and standard CMOS process, which benefits from having a 100% fill factor and embedded front-end electronics.
Marco Mandurrino   +5 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reduced-complexity timing detectors for MC-CDMA signals

open access: yes, 2006
In this paper, two reduced-complexity timing detectors for MC-CDMA signals based on incorporating the on-time arm in timing error signal update are proposed and analyzed. By theoretical analysis and simulations, it is shown that the simplified approaches
Wu, Luo   +5 more
core   +1 more source

Sub-barrier fusion cross section measurements with STELLA

open access: yesEPJ Web of Conferences, 2017
The experimental setup STELLA (STELlar LAboratory) is designed for the measurement of deep sub-barrier light heavy ion fusion cross sections. For background suppression the γ-particle coincidence technique is used.
Heine M.   +21 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Recent Technological Developments on LGAD and iLGAD Detectors for Tracking and Timing Applications

open access: yes, 2015
This paper reports the latest technological development on the Low Gain Avalanche Detector (LGAD) and introduces a new architecture of these detectors called inverse-LGAD (iLGAD).
Stricker, M.   +17 more
core   +1 more source

Rethinking timing residuals: advancing PET detectors with explicit TOF corrections

open access: yesFrontiers in Physics
PET is a functional imaging method that can visualize metabolic processes and relies on the coincidence detection of emitted annihilation quanta. From the signals recorded by coincident detectors, TOF information can be derived, usually represented as ...
Stephan Naunheim   +13 more
doaj   +1 more source

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