A comparative study between two stability-indicating chromatographic methods for the assay of brinzolamide and timolol maleate in the co-existence of the probable carcinogenic oxidative degradation product of timolol maleate in their ophthalmic ...
Asmaa A. Mandour +4 more
doaj +2 more sources
Ocular surface evaluation in patients treated with a fixed combination of prostaglandin analogues with 0.5% timolol maleate topical monotherapy: a randomized clinical trial [PDF]
OBJECTIVES: To compare ocular surface changes induced via glaucoma treatment in patients using fixed combinations of prostaglandin analogues (travoprost, latanoprost and bimatoprost) with 0.5% timolol maleate METHODS: A prospective, multicenter ...
Heloisa Helena Russ +6 more
doaj +4 more sources
Optimization of Thermoreversible In Situ Nasal Gel of Timolol Maleate [PDF]
Nasal route had shown better systemic bioavailability due to its large surface area, porous endothelial membrane, high total blood flow, and avoidance of first-pass metabolism.
Swati Jagdale +2 more
doaj +2 more sources
Timing and Efficacy of 595-nm Pulsed-Dye Laser Combined with 0.5% Timolol Maleate Solution in the Treatment of Superficial Infantile Hemangiomas [PDF]
Weikang Shi,* Huiyi He,* Jicong Jiang, Yu Gao, Hehe Quan Department of Dermatology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, 325027, Zhejiang Province, People’s Republic of China&ast ...
Shi W, He H, Jiang J, Gao Y, Quan H
doaj +2 more sources
Development and evaluation of polycaprolactone-based electrospun nanofibers containing timolol maleate as a sustained-release device for treatment of glaucoma: in vivo evaluation in equine eye. [PDF]
Background and purpose: Prolonging the drug release can be a suitable approach to overcome the challenges related to topical ophthalmic administration of drugs especially the ones prescribed for chronic ailments.
Mirzaeei S +5 more
europepmc +2 more sources
Safety and efficacy of switching from dorzolamide 1.0%/timolol maleate 0.5% eye drops to brinzolamide 1.0%/timolol maleate 0.5% eye drops [PDF]
Kenji Inoue,1 Minako Shiokawa,1 Kyoko Ishida,2 Goji Tomita2 1Inouye Eye Hospital, Tokyo, Japan; 2Department of Ophthalmology, Toho University Ohashi Medical Center, Tokyo, Japan Purpose: To evaluate the safety and efficacy of switching from dorzolamide
Inoue K, Shiokawa M, Ishida K, Tomita G
doaj +2 more sources
Infantile Hemangiomas with Minimal and Arrested Growth: Clinical Features and Treatment Outcomes with 0.5% Topical Timolol Maleate. [PDF]
Background A minority of infantile hemangiomas showing minimal or arrested growth (IH-MAGs) have been recognized in the literature. Nevertheless, the clinical features and treatment outcomes of IH-MAGs have not been well investigated.
Bae KN +5 more
europepmc +2 more sources
The impact of timolol maleate on the ocular tolerability of fixed-combination glaucoma therapies [PDF]
Nathan M Radcliffe Ophthalmology, New York University, New York, NY, USA Abstract: Glaucomatous optic atrophy is the second most common cause of blindness worldwide, and lowering intraocular pressure (IOP) is the only proven method to slow or stop the ...
Radcliffe NM
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Peptide dendrimer and hyaluronic acid modified nanovesicles for ocular delivery of timolol maleate and siRNA. [PDF]
Glaucoma, a leading cause of irreversible blindness, is characterized by retinal ganglion cell (RGC) degeneration due to elevated intraocular pressure (IOP) and apoptosis.
Naik S +3 more
europepmc +2 more sources
Topical timolol for superficial cutaneous infantile hemangiomas in very preterm infants [PDF]
Introduction. Infantile hemangiomas (IHs) occur 3 to 4 times more frequently in preterm infants than in those born at term. Yet, data about efficacy and safety of topical therapy for IHs in preterm infants, especially in those born with very low ...
Matić Aleksandra +2 more
doaj +1 more source

