Results 11 to 20 of about 4,471 (177)

Changes in visual function after intraocular pressure reduction using antiglaucoma medications [PDF]

, 2009
Purpose To evaluate the change in visual function after starting glaucoma treatment and correlate this to a decrease in intraocular pressure (IOP) in primary open-angle glaucoma patients.Methods A prospective, randomized clinical trial was carried out ...
A Harris, A Heijl, AS Hawkins, C Holmin, CS Tsai, D Regan, DW Evans, DW Evans, GN Pomerance, HA Quigley, J Flammer, JE Ross, JS Pointer, L A S Melo, LJ Katz, M V Piassi, O Arend, RN Weinreb, S Salim, SA Gandolfi, SA Gandolfi, T S Prata, WC Stewart   +22 more
core   +2 more sources

Safety and efficacy of travoprost solution for the treatment of elevated intraocular pressure [PDF]

, 2015
Travoprost is a prostaglandin analogue widely used for reducing intraocular pressure (IOP) in patients affected with glaucoma and ocular hypertension. It exerts its ocular hypotensive effect through the prostaglandin FP receptors, located in the ciliary ...
Centofanti, Marco, Floriani, Irene, Katsanos, Andreas, Konstas, Anastasios, Quaranta, Luciano, Riva, Ivano   +5 more
core   +2 more sources

Current Knowledge and Attitudes Concerning Cost-Effectiveness in Glaucoma Pharmacotherapy: A Glaucoma Specialists Focus Group Study. [PDF]

, 2020
Background:Rising healthcare costs motivate continued cost-reduction efforts. To help lower costs associated with open-angle glaucoma (OAG), a prevalent, progressive disease with substantial direct and indirect costs, clinicians need to understand the ...
Cioffi, George A, Feldman, Robert M, Feldman, Robert M, Liebmann, Jeffrey M, Weinreb, Robert N   +4 more
core  

Efficacy and safety of timolol maleate/latanoprost fixed combination versus timolol maleate and brimonidine given twice daily [PDF]

Acta Ophthalmologica Scandinavica, 2003
Abstract.Purpose:  To evaluate the efficacy and safety of the timolol maleate/latanoprost fixed combination (TLFC) given once each evening versus brimonidine and timolol solution given twice daily as concomitant therapy in primary open‐angle glaucoma or ocular hypertension patients.Methods:  Qualified subjects were begun on timolol alone twice daily ...
William C, Stewart, Jeanette A, Stewart, Douglas, Day, Elizabeth D, Sharpe   +3 more
openaire   +2 more sources

Alteração do filme lacrimal e superfície ocular em usuários crônicos de medicação antiglaucomatosa [PDF]

, 2008
PURPOSE: Tear film can be altered by chronic medications that may disrupt the equilibrium responsible for the functioning of the lacrimal gland and ocular surface.
BAFFA, Lina do Prado, BRAZ, Alexandre Martins, DIAS, Ana Carolina, MÓDULO, Carolina Maria, PAULA, Jayter Silva de, RICARDO, Jose Reinaldo da Silva, ROCHA, Eduardo Melani, RODRIGUES, Maria de Lourdes Veronese   +7 more
core   +2 more sources

Approaches in topical ocular drug delivery and developments in the use of contact lenses as drug-delivery devices [PDF]

, 2017
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Drug-delivery approaches have diversified over the last two decades with the emergence of nanotechnologies,
Acheampong A, Bar-Ilan A, Do MP, Forrester JV, Gasmi H, Giannaccare G, Lin MC, Nijhawan R, Patel PB, Pratt NL, Schaeffer HE, Schopf LR, Smolin G, Song HB, Waltman SR, Wei J, Wheeler J, Xu X   +17 more
core   +2 more sources

Development of an Efficient and Scalable Process for Preparing Timolol N‐Nitrosamine Impurities B, C, E, H, I, J, and Their ADMET Evaluation

Journal of Heterocyclic Chemistry, EarlyView.
N‐nitrosamine impurities (B, C, E, H, I, J) of timolol maleate are easily synthesized from diethyl malonate and 3,4‐dichloro‐1,2,5‐thiadiazole. Good yields and precise impurity profiling are made possible by the effective technique, which also ensures pharmaceutical safety and strengthens regulatory compliance.
Kottolla Sai Prasad, Chithaluri Sudhakar, Vijaya Krishna Ravi, Bijaya Kethan Sahoo   +3 more
wiley   +1 more source

Topical Timolol Maleate Treatment of Infantile Hemangiomas

Pediatrics, 2016
BACKGROUND: There has been a dramatic increase in the off-label use of ophthalmic timolol maleate, a β-blocker used for infantile hemangioma (IH) treatment as a topical counterpart to oral propranolol. Its safety and efficacy in a pediatric population with IH have not been evaluated in a large cohort.
Puttgen, K, Lucky, A, Adams, D, Pope, E, McCuaig, C, Powell, J, Feigenbaum, D, Savva, Y, Baselga, E, Holland, K, Drolet, B, Siegel, D, Morel, KD, Garzon, MC, Mathes, E, Lauren, C, Nopper, A, Horii, K, Newell, B, Song, W, Frieden, I   +20 more
openaire   +3 more sources

Ulcerated Infantile Hemangioma of the Intergluteal Cleft Treated with Topical Timolol [PDF]

, 2013
Dados recentes revelam resultados promissores com a utilização de beta-bloqueante tópico no tratamento dos hemangiomas infantis ulcerados. Os autores descrevem o caso clínico de uma lactente pré-termo de 6 meses de idade com um hemangioma infantil ...
Amaro, C, Cardoso, J, Fernandes, S
core   +2 more sources

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source