Results 141 to 150 of about 1,611,997 (328)
Alternative measure for education variable in an empirical economic growth model: Is primary education less important? [PDF]
In this paper, an alternative measure of the education variable is proposed in an empirical economic growth model. Taiwan from 1964-2000 is selected as a case study.
Tin-Chun Lin
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
KHAI KHOÁNG VÀ ỨNG DỤNG CỦA MẪU EPISODE MỞ RỘNG TRÊN DỮ LIỆU PHỤ THUỘC THỜI GIAN
Tạp chí Khoa học Đại học Cần Thơ, 2013 Trong bài viết này, chúng tôi giới thiệu mô hình mẫu episode mở rộng phát triển từ mô hình mẫu episode với dữ liệu phụ thuộc vào thời gian. Dựa trên mô hình vừa trình bày, chúng tôi giới thiệu giải thuật khai khoáng mẫu episode mở rộng chỉ duyệt qua ...
Nguyễn Bá Diệp +3 more
doaj
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
XÂY DỰNG CÔNG CỤ NGĂN CHẶN VIỆC TRUY CẬP WEB ĐEN (HÌNH ẢNH, NỘI DUNG)
Tạp chí Khoa học Đại học Cần Thơ, 2013 Công cụ lọc web (web filtering) được sử dụng để ngăn chặn việc truy cập đến các trang web đen (trang web mang nội dung hoặc hình ảnh không mong muốn). Trong bài báo này, chúng tôi ứng dụng phương pháp phân lớp với Máy học vector hỗ trợ (SVM) để xây dựng ...
Huỳnh Bé Thơ +1 more
doaj
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source