Results 171 to 180 of about 1,374,449 (299)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Urinary CD4⁺ T helper cells are a potential biomarker for tubulointerstitial nephritis in Sjögren's disease. [PDF]

Sci Rep
Laas V, Feindt FC, Böse P, Zimmermann T, Klimicevs P, Hagenstein J, Ehnold LI, Herrnstadt GR, Warkotsch MT, Paust HJ, Panzer U, Krebs CF, Huber TB, Wiech T, Steinmetz OM, Melderis S.   +15 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Mechanical Nitriding of Titanium and Its Alloys as a Feedstock for the Additive Manufacturing of Functionally Graded Materials. [PDF]

Materials (Basel)
Antolak-Dudka A, Liszewska M, Dyjak S, Wyrębska I, Czujko T, Polański M.   +5 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

HfO₂-based memristive synapses with asymmetrically extended p-n heterointerfaces for highly energy-efficient neuromorphic hardware. [PDF]

Sci Adv
Bakhit B, Xie X, Fairclough SM, Jan A, Persson I, Di Martino G, Zhu B, Ducati C, Jia Q, Yildiz B, Flewitt AJ, MacManus-Driscoll JL.   +11 more
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Capturing the inflammatory landscape within kidney compartments of human diabetic kidney disease: a digital spatial profiling study. [PDF]

Front Endocrinol (Lausanne)
Elhusseiny KM, Deceus FG, Cornell LD, Bian X, Ma Y, Kachergus JM, Thompson EA, Hickson LJ.   +7 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Optimizing the drilling performance of Syagrus romanzoffiana fiber biocomposites: minimizing delamination with RSM and ANN modeling. [PDF]

Sci Rep
Ferfari O, Belaadi A, Krishnasamy P, Ghernaout D, Mukalazi H.   +4 more
europepmc   +1 more source