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Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Straightforward Donor Atom Switching: From P,C,P- to Various Y,C,Y-Pincer (Y = O, S, Se) Organotin(IV) Compounds and Cations. [PDF]

open access: yesInorg Chem
Chlebík R   +6 more
europepmc   +1 more source

A Rapid-prototyping CMOS-RRAM Integration Strategy. [PDF]

open access: yesMicrosyst Nanoeng
Tsiamis A   +2 more
europepmc   +1 more source
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Heterogeneous 2D/3D Tin‐Halides Perovskite Solar Cells with Certified Conversion Efficiency Breaking 14%

Advanced Materials, 2021
As the most promising lead‐free one, tin‐halides based perovskite solar cells still suffer from the severe bulk‐defect due to the easy oxidation of tin from divalent to tetravalent.
Bin-Bin Yu, Zhenhua Chen, Yudong Zhu
exaly   +2 more sources

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