Results 41 to 50 of about 160,183 (291)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Numerical Investigation into the Effects of Tip Clearance on the Performance of a Counter-Rotating Axial Flow Compressor

open access: yesJournal of Applied Fluid Mechanics, 2020
The impact of varying the tip clearance of each rotor on the performance of a counter-rotating axial compressor has been investigated based on numerical simulations.
T. Liang   +4 more
doaj  

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Evaluating the Effects of Blade Tip Clearance in Various Stages on the Performance of an Axial Compressor

open access: yesJournal of Applied Fluid Mechanics, 2018
In the current study, the influence of blade tip clearance in different stages of a three-stage compressor is investigated. Performance diagrams of compressor were verified against experiment when there is no change in the tip clearance, after which the ...
M. Ostad, R. Kamali
doaj  

Flow and Fast Fourier Transform Analyses for Tip Clearance Effect in an Operating Kaplan Turbine

open access: yesEnergies, 2019
The Kaplan turbine is an axial propeller-type turbine that can simultaneously control guide vanes and runner blades, thus allowing its application in a wide range of operations.
Hyoung-Ho Kim   +3 more
doaj   +1 more source

Numerical Investigation on Flow Field Distribution of Eccentric Compressors Based on Steady and Unsteady CFD Methods

open access: yesEnergies, 2020
The tip clearance has an important effect on the performance of an engine compressor. While the impact of tip clearance on a concentric compressor has been widely explored in previous research, the flow field distribution of an eccentric compressor has ...
Chao Jiang   +3 more
doaj   +1 more source

Centrifugal compressor tip clearance and impeller flow [PDF]

open access: yesJournal of Mechanical Science and Technology, 2016
Compressors consume a considerable portion of the electricity used in the industrial sector. Hence, improvements in compressor efficiency lead to energy savings and reduce environmental impacts. The efficiency of an unshrouded centrifugal compressor suffers from leakage flow over the blade tips.
Jaatinen-Värri, Ahti   +6 more
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

An Investigation on the Effect of Blade Tip Clearance on the Performance of a Single-Stage Axial Compressor

open access: yesJournal of Applied Fluid Mechanics, 2019
In the present study, the numerical analysis of blade tip geometry effect on the performance of a single-stage axial compressor has been the focus of attention. The studied geometries included a rotor with variable tip clearance. For the first model, the
M. Ostad, R. Kamali
doaj  

Effects of a Nonuniform Tip Clearance Profile on the Performance and Flow Field in a Centrifugal Compressor

open access: yesInternational Journal of Rotating Machinery, 2012
This paper presents a numerical investigation of the effects of a nonuniform tip clearance profile on the performance and flow field in a centrifugal compressor with a vaneless diffuser.
Yohan Jung   +3 more
doaj   +1 more source

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