Results 71 to 80 of about 976,747 (247)
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Development of a Simulation Model for Blade Tip Timing with Uncertainties
AerospaceBlades are widely used in the engines of aerospace vehicles, fans of near-space aerostat, and other equipment, and they are the key to completing energy conversion and pressure adjustment of the capsule.
Kang Chen +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Large Tip Clearance Flows in High Pressure Stages of Axial Compressors [PDF]
, 2009 This thesis investigates over tip leakage where the tip clearance is large. In the high pressure stages of axial compressors the tip clearance can be typically 6% of span and the total blockage due to tip clearance can consume in excess of forty percent ...
WILLIAMS, RICHARD,JAMES
core
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
FEBS Open Bio, EarlyView.Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source
Modelling of 4WD vehicle driveability during tip-in/tip-out events [PDF]
, 2011 This paper describes a modelling method to investigate the dynamic behaviour of 4WD vehicle under a severe driving condition, where the driver applies a rapid tip-in on the accelerator pedal in 2nd gear to achieve maximum engine torque.
Bin Raja Ahsan Shah, Raja Mazuir +3 more
core
Landing control of a magnetically actuated robotic catheter on beating heart surface
Scientific ReportsIn this paper, the problem of a magnetically actuated robotic catheter landing on a beating heart surface for the robotic catheter ablation procedure is addressed.
Ran Hao, M. Cenk Cavuşoğlu
doaj +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Nonlinear Vibrations of Low Pressure Turbine Bladed Disks: Tests and Simulations
Applied SciencesOne of the most effective methods to limit the mechanical vibrations of bladed disks is the use of friction damping at mechanical joint interfaces. Unfortunately, dedicated tests to assess the impact of mistuning and the effectiveness of friction dampers
Umidjon Usmanov +5 more
doaj +1 more source