Results 81 to 90 of about 72,876 (262)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Development of a Simulation Model for Blade Tip Timing with Uncertainties

open access: yesAerospace
Blades are widely used in the engines of aerospace vehicles, fans of near-space aerostat, and other equipment, and they are the key to completing energy conversion and pressure adjustment of the capsule.
Kang Chen   +3 more
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

A subspace method for modal identification of bladed assemblies using blade tip-timing data

open access: yes, 2007
International audienceUnknown excitation forces are applied to bladed disk assemblies, such as turbines blades, leading to forced vibration responses.
Salhi, Bendali   +4 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

REFINEMENT OF A SPRAY TIMING TECHNIQUE FOR THE NANTUCKET PINE TIP MOTH (LEPIDOPTERA: TORTRICIDAE)

open access: yes, 1988
Application of dimethoate on various spray dates enabled a refinement of a spray timing technique for control of the third generation of Nantucket pine tip moth.
Louis H. Kudon   +2 more
core   +1 more source

Nonlinear Vibrations of Low Pressure Turbine Bladed Disks: Tests and Simulations

open access: yesApplied Sciences
One of the most effective methods to limit the mechanical vibrations of bladed disks is the use of friction damping at mechanical joint interfaces. Unfortunately, dedicated tests to assess the impact of mistuning and the effectiveness of friction dampers
Umidjon Usmanov   +5 more
doaj   +1 more source

Simulation of the response of the inner hair cell stereocilia bundle to an acoustical stimulus.

open access: yesPLoS ONE, 2011
Mammalian hearing relies on a cochlear hydrodynamic sensor embodied in the inner hair cell stereocilia bundle. It is presumed that acoustical stimuli induce a fluid shear-driven motion between the tectorial membrane and the reticular lamina to deflect ...
Sonya T Smith, Richard S Chadwick
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

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