Results 81 to 90 of about 976,747 (247)
Simulation of the response of the inner hair cell stereocilia bundle to an acoustical stimulus.
PLoS ONE, 2011 Mammalian hearing relies on a cochlear hydrodynamic sensor embodied in the inner hair cell stereocilia bundle. It is presumed that acoustical stimuli induce a fluid shear-driven motion between the tectorial membrane and the reticular lamina to deflect ...
Sonya T Smith, Richard S Chadwick
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
The Measurement of Turbomachinery Blade Vibration Through Tip Timing With Capacitance Tip Clearance Probes [PDF]
, 2020 Turbomachinery blade vibrations can cause High Cycle Fatigue, which reduces blade life. In order to observe this vibration a non-intrusive monitoring system is sought.
Paul C Ivey +2 more
core
Determining Rotor Blade Multi-Mode Vibration Components
Applied SciencesThe new algorithm presented in this paper determines the multi-mode blade vibration components when the time of blade arrival is known from an experiment.
Jerzy Manerowski +3 more
doaj +1 more source
Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells
FEBS Open Bio, EarlyView.Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
The tip complex of the "Yersinia enterocolitica" injectisome [PDF]
, 2008 Type III secretion systems are used by many pathogenic bacteria to deliver effector proteins into host cells. The secretion machinery, also known as the injectisome, is composed of a basal body anchored in the bacterial membranes and an external needle ...
Müller, Catherine Ann
core +1 more source
Nature CommunicationsSegmented filamentous bacteria (SFB) are intestinal commensals that promote immune system development and pathogen protection through intimate attachment to the ileal epithelium.
Ana Raquel Cruz +14 more
doaj +1 more source
Tip-timing analysis of last stage steam turbine mistuned bladed disc during run-down
MATEC Web of Conferences, 2018 This paper presents the experimental and numerical studies of last stage LP mistuned steam turbine bladed discs during run-down. The natural frequencies and mode shapes of the turbine bladed disc were calculated using an FE model.
Rzadkowski Romuald +5 more
doaj +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source