Results 31 to 40 of about 35,214 (259)

Ineffectiveness of tirzepatide in mitigating Doxorubicin-induced oxidative stress and cognitive deficits in a rat model

open access: yesFrontiers in Pharmacology
Doxorubicin (DXN) is widely utilized for the treatment of various cancer types. However, prolonged DXN administration induces vascular impairment and neurological effects, including cognitive deficits.
Salma A. Alolayan, Ahmad H. Alhowail
doaj   +1 more source

Enzymatic Functions for Toll/Interleukin-1 Receptor Domain Proteins in the Plant Immune System

open access: yesFrontiers in Genetics, 2020
Rationally engineered improvements to crop plants will be needed to keep pace with increasing demands placed on agricultural systems by population growth and climate change.
Adam M. Bayless, Marc T. Nishimura
doaj   +1 more source

Laser‐Induced Graphene from Waste Almond Shells

open access: yesAdvanced Functional Materials, EarlyView.
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova   +9 more
wiley   +1 more source

Human and Bacterial Toll-Interleukin Receptor Domains Exhibit Distinct Dynamic Features and Functions

open access: yesMolecules, 2022
Toll-interleukin receptor (TIR) domains have emerged as critical players involved in innate immune signaling in humans but are also expressed as potential virulence factors within multiple pathogenic bacteria.
Eunjeong Lee   +8 more
doaj   +1 more source

Giant Anisotropy and High Second‐Order Nonlinearity of 3R‐MoS2 for Multifunctional Photonics

open access: yesAdvanced Materials, EarlyView.
Graphical abstract highlights, 3R‐polytype of MoS2 (3R‐MoS2) as a multifunctional photonic platform enabled by giant optical anisotropy and optical nonlinearities, demonstrating subdiffractional waveguiding, giant second‐harmonic (SH) generation, and high‐performance reflective polarization control.
Georgy Ermolaev   +17 more
wiley   +1 more source

High resolution mapping of trypanosomosis resistance loci Tir2 and Tir3 using F12 advanced intercross lines with major locus Tir1 fixed for the susceptible allele

open access: yesBMC Genomics, 2010
Background Trypanosomosis is the most economically important disease constraint to livestock productivity in Africa. A number of trypanotolerant cattle breeds are found in West Africa, and identification of the genes conferring trypanotolerance could ...
Soller Morris   +2 more
doaj   +1 more source

Digital Twin of a One‐Sun‐Driven Luminescent‐Concentrator‐Assisted Planar Solar‐Pumped Fiber Laser

open access: yesAdvanced Optical Materials, EarlyView.
An experimentally‐validated digital twin of a one‐sun solar‐pumped fiber laser enables a design exhibit 13‐times higher output power at 1064 nm to be achieved. Despite its simple appearance, the multitude of choices in the design parameters make finding this improved very tedious in the lab, thus the digital twin can save significant time and effort ...
Anvarjon Sherniyozov   +2 more
wiley   +1 more source

Control of Type III Secretion System Effector/Chaperone Ratio Fosters Pathogen Adaptation to Host-Adherent Lifestyle

open access: yesmBio, 2019
The transition from a planktonic lifestyle to a host-attached state is often critical for bacterial virulence. Upon attachment to host cells, enteropathogenic Escherichia coli (EPEC) employs a type III secretion system (T3SS) to inject into the host ...
Netanel Elbaz   +3 more
doaj   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

open access: yesAdvanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Association between time in range and cancer mortality among patients with type 2 diabetes: a prospective cohort study

open access: yesChinese Medical Journal, 2022
. Background:. Little was known about the association among time in range (TIR), time above range (TAR), time below range (TBR), and cancer mortality among patients with type 2 diabetes.
Yun Shen   +11 more
doaj   +1 more source

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