Results 41 to 50 of about 35,159 (258)

Control of Type III Secretion System Effector/Chaperone Ratio Fosters Pathogen Adaptation to Host-Adherent Lifestyle

open access: yesmBio, 2019
The transition from a planktonic lifestyle to a host-attached state is often critical for bacterial virulence. Upon attachment to host cells, enteropathogenic Escherichia coli (EPEC) employs a type III secretion system (T3SS) to inject into the host ...
Netanel Elbaz   +3 more
doaj   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

TIR over Egyptian Hieroglyphs [PDF]

open access: yes2016 27th International Workshop on Database and Expert Systems Applications (DEXA), 2016
Ministerio de Economía y Competitividad; FFI2014-51978-C2-2 ...
Estíbaliz Iglesias-Franjo   +1 more
openaire   +2 more sources

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

amo [PDF]

open access: yesپژوهش در نظام‌های آموزشی, 2013
چکیده نظام آموزش عالی مغز متفکر جامعه و اردوگاه علم جدید است. بدون تردید دانشگاه آزاد اسلامی نقش غیر قابل انکاری در توسع ۀ علمی و پژوهشی کشور ایفا کر ده است، اما در سالهای اخیر این دانشگاه با کاهش تقاضای ورود دانشجو مواجه شده است، این طرح پژوهشی با هدف ...
hada tir
doaj  

Leveraging Big Multitemporal Multisource Satellite Data and Artificial Intelligence for the Detection of Complex and Invisible Features: The Case of Extensive Irrigation Mapping

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT The detection of buried or obscured archaeological features remains a central challenge in landscape archaeology, particularly in the irrigated floodplains of Mesopotamia where levees and canals formed the basis of complex agrarian systems. This study presents a deep learning–based approach for the large‐scale, automated detection of ancient ...
Nazarij Buławka   +4 more
wiley   +1 more source

Outline and Impact of Firms Related to the Third Industrial Revolution: Investigation through Big Data

open access: yesSmart Cities, 2022
This article is focusing on the dynamism of the Third Industrial Revolution (TIR) in the region Hauts-de-France between 2013 and 2018. Region Hauts-de-France has been a forerunner in setting up a proactive policy in favour of the TIR.
Matthieu Belarouci
doaj   +1 more source

The Role of TIR-NBS and TIR-X Proteins in Plant Basal Defense Responses [PDF]

open access: yesPLANT PHYSIOLOGY, 2013
Toll/interleukin receptor (TIR) domain-containing proteins encoded in the Arabidopsis (Arabidopsis thaliana) genome include the TIR-nucleotide binding site (TN) and TIR-unknown site/domain (TX) families. We investigated the function of these proteins. Transient overexpression of five TX and TN genes in tobacco (Nicotiana benthamiana) induced chlorosis.
Raja Sekhar, Nandety   +6 more
openaire   +2 more sources

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

open access: yesBiotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady   +6 more
wiley   +1 more source

Discharge Remote Monitoring Systems for Glycemic Management After Hospital Discharge

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Heat map of median number of telehealth interactions by subgroup and theme. Major themes identified included intervention after remote monitoring alerts (e.g., “Team reached out to participant and instructed participant to treat hypo.”), insulin dose adjustments (e.g., “Participant reported that prednisone dose is increasing … Called to discuss insulin
Nirali Shah   +14 more
wiley   +1 more source

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