Transcription of TIR1-controlled Genes Can be Regulated within 10 Minutes by an Auxin-induced Process. Can TIR1 be the Receptor? [PDF]
ABP1 and TIR1/AFBs are known as auxin receptors. ABP1 is linked to auxin responses several of which are faster than ten minutes. TIR1 regulates auxin-induced transcription of early auxin genes also within minutes.
Corinna Labusch +3 more
doaj +7 more sources
A novel mechanism of auxin habituation: upregulation of auxin receptor TRANSPORT INHIBITOR RESPONSE 1 allows cell proliferation independent of external auxin. [PDF]
Summary Exogenously applied auxins are essential for establishing cell lines in tissue cultures and maintaining their proliferation. Cell lines may develop the ability to proliferate even in media lacking auxin, they may become auxin‐habituated. This study investigated the mechanisms underlying this process.
Jelínek P +11 more
europepmc +2 more sources
A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice. [PDF]
African trypanosomes are protozoan parasites that cause "sleeping sickness" in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) that regulate survival time after infection ...
Ian Goodhead +10 more
doaj +7 more sources
Engineering the auxin-inducible degron system for tunable in vivo control of organismal physiology [PDF]
The auxin-inducible degron (AID) system is designed for the rapid and near-complete degradation of a specific target protein in vivo. However, to understand the dynamics of complex physiological networks, researchers often need methods that produce ...
Jeremy Vicencio +5 more
doaj +2 more sources
Development of functional fermented feed additives enhanced with xylo-oligosaccharides and yeast proteins from corn cobs [PDF]
The use of agricultural by-products, such as corn cobs, has gained significant attention as a sustainable and promising strategy for developing functional feed additives.
Gayoung Lee, In Jung Kim, Soo Rin Kim
doaj +2 more sources
Primed to Burst: Corepressors Coordinate Transcriptional Activation and Efficient Switching Between Cell States. [PDF]
We hypothesize that the TPL corepressor (and likely others) acts as a transcriptional linchpin, stabilizing a state similar yet distinct from the metazoan paused state by recruiting Mediator and other components needed to initiate and coordinate transcriptional bursts across multiple genes.
Leydon AR, Nemhauser JL.
europepmc +2 more sources
A moderate increase in temperature promotes hypocotyl elongation in Arabidopsis. Here, Wang et al.show that elevated temperature not only increases auxin biosynthesis but also acts via the co-chaperones HSP90 and SGT1 to stabilize the TIR1 auxin receptor.
Martin L Kieffer +2 more
exaly +2 more sources
Tomographic docking suggests the mechanism of auxin receptor TIR1 selectivity [PDF]
We study the binding of plant hormone IAA on its receptor TIR1, introducing a novel computational method that we call tomographic docking and that accounts for interactions occurring along the depth of the binding pocket.
Veselina V. Uzunova +3 more
doaj +6 more sources
miRNA-targeted auxin nuclear signalling elements orchestrate flower fate and drought response in yellow lupine [PDF]
Yellow lupine (Lupinus luteus L.) is a promising protein crop, but domestication has increased flower abscission. Flowers in higher whorls are more likely to abscise, providing a model to study factors influencing flower fate before abscission zone ...
Milena Kulasek, Paulina Glazińska
doaj +2 more sources
Regulation of SCFTIR1/AFBs E3 ligase assembly by S-nitrosylation of Arabidopsis SKP1-like1 impacts on auxin signaling [PDF]
The F-box proteins (FBPs) TIR1/AFBs are the substrate recognition subunits of SKP1–cullin–F-box (SCF) ubiquitin ligase complexes and together with Aux/IAAs form the auxin co-receptor.
María José Iglesias +13 more
doaj +5 more sources

