A plant NLR receptor activates auxin signaling through Aux/IAAs-ARF19 and YUC8-TIR1/AFBs to promote callose-mediated antiviral defense. [PDF]
Phytohormone signaling pathways are crucial for defense against pathogens mediated by pattern recognition receptors and nucleotide-binding leucine-rich repeat (NLR) immune receptors.
Yang T +18 more
europepmc +3 more sources
TIR1/AFB proteins: Active players in abiotic and biotic stress signaling [PDF]
The TIR1/AFB family of proteins is a group of functionally diverse auxin receptors that are only found in plants. TIR1/AFB family members are characterized by a conserved N-terminal F-box domain followed by 18 leucine-rich repeats.
Wenchao Du +6 more
doaj +3 more sources
Unveiling the role of the TIR1/AFB gene family in Capsicum annuum: genome-wide identification, characterization, and transcriptomic analysis under Ralstonia solanacearum infection [PDF]
TIR1/AFB proteins play key roles in plants responding to Solanum crop disease. In this study, five putative TIR1/AFB proteins were identified in pepper (Capsicum annuum). Chromosomal mapping revealed that CaTIR1/AFB genes are located on chromosomes DH02,
Wenchao Du +10 more
doaj +3 more sources
To Bind or Not to Bind? A Comprehensive Characterization of TIR1 and Auxins Using Consensus In Silico Approaches [PDF]
Auxins are chemical compounds of wide interest, mostly due to their role in plant metabolism and development. Synthetic auxins have been used as herbicides for more than 75 years and low toxicity in humans is one of their most advantageous features ...
Fernando D. Prieto-Martínez +2 more
doaj +3 more sources
Comparative genomic profiling of transport inhibitor Response1/Auxin signaling F-box (TIR1/AFB) genes in eight Pyrus genomes revealed the intraspecies diversity and stress responsiveness patterns [PDF]
In the genomics of plants and the phytoecosystem, Pyrus (pear) is among the most nutritious fruits and contains fiber that has great health benefits to humans.
Sheng Yang +4 more
doaj +3 more sources
Tomographic docking suggests the mechanism of auxin receptor TIR1 selectivity [PDF]
We study the binding of plant hormone IAA on its receptor TIR1 introducing a novel computational method that we call tomographic docking and that accounts for interactions occurring along the depth of the binding pocket.
del Genio, Charo +3 more
core +8 more sources
A Combinatorial TIR1-Aux/IAA Co-Receptor System for Peach Fruit Softening
Fruit softening is an important characteristic of peach fruit ripening. The auxin receptor TIR1 (Transport Inhibitor Response 1) plays an important role in plant growth and fruit maturation.
Yutong Zhao +5 more
doaj +4 more sources
Transcription of TIR1-Controlled Genes Can be Regulated within 10 Min by an Auxin-Induced Process. Can TIR1 be the Receptor? [PDF]
ABP1 and TIR1/AFBs are known as auxin receptors. ABP1 is linked to auxin responses several of which are faster than 10 min. TIR1 regulates auxin-induced transcription of early auxin genes also within minutes.
Effendi, Yunus +3 more
core +8 more sources
Background The plant hormone auxin is widely involved in plant growth, development, and morphogenesis, and the TIR1/AFB and AUX/IAA proteins are closely linked to rapid auxin response and signal transmission.
Liyao Su +9 more
doaj +2 more sources
A spontaneous TIR1 loss-of-function allele in C. elegans [PDF]
The auxin-inducible degron (AID) system is a widely-used system for conditional protein depletion. During the course of an experiment, we depleted the nuclear hormone receptor transcription factor NHR-23 to study molting, and we recovered a spontaneous ...
Krista M. Myles +3 more
semanticscholar +2 more sources

