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Rational Design of an Auxin Antagonist of the SCFTIR1 Auxin Receptor Complex

ACS Chemical Biology, 2012
The plant hormone auxin is a master regulator of plant growth and development. By regulating rates of cell division and elongation and triggering specific patterning events, indole 3-acetic acid (IAA) regulates almost every aspect of plant development. The perception of auxin involves the formation of a ternary complex consisting of an F-box protein of
Ken-ichiro, Hayashi   +6 more
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Incidental thyroid carcinoma in patients with TIR1, TIR2 and TIR3 FNA.

Annali italiani di chirurgia, 2019
The aim of our study was to evaluate the presence of incidental differentiated thyroid carcinomas, at final histological examination, in patients undergoing thyroidectomy or lobectomy for presumed benign pathology or in those with cytological diagnosis of indeterminate nodules (TIR3).457 patients who underwent surgery for benign disease and 179 ...
Angela, Pezzolla   +6 more
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Adenylate cyclase activity of TIR1/AFB links cAMP to auxin-dependent responses

Molecular Plant, 2022
Aloysius Wong   +3 more
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Auxin and TIR1 Ubiquitin Ligase

RCSB Protein Data Bank, 2009
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Teaching resources. Model of the TIR1 pathway for auxin-mediated gene expression.

Science's STKE : signal transduction knowledge environment, 2006
Auxin mediates numerous plant responses, some of which have been shown to require transcriptional regulation. One auxin response pathway, which depends on the relief of transcriptional repression, is mediated by TIR1 (transport inhibitor response protein 1). TIR1 is an auxin receptor and also a subunit of an SCF-type ubiquitin ligase.
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TIR1 Non-diagnostic

Francesco Nardi   +3 more
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Identifikace cytoplazmatického TIR1/AFB receptorového komplexu auxinu v Arabidopsis thaliana

Auxin is a phytohormone involved in many aspects of plant growth and development. The core of auxin action lies in its well-described signalling pathway, which leads to regulation of gene expression. Key players of this pathway include the TIR1/AFB receptors and Aux/IAAs coreceptors acting as transcriptional repressors, which are degraded upon auxin ...
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