Results 1 to 10 of about 10,271 (191)
Local tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban ASSIST study [PDF]
BMC Neurology, 2020 Background Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT).
Yong-Won Kim +11 more
doaj +4 more sources
Tirofiban-induced acute profound thrombocytopenia in endovascular therapy for acute ischemic stroke: a rare case report [PDF]
BMC NeurologyBackground Studies have shown that tirofiban (a glycoprotein IIb/IIIa receptor antagonist) is effective in the endovascular treatment of cerebrovascular diseases. However, it has also been reported that tirofiban can cause thrombocytopenia.
Jiuling Liu +4 more
doaj +2 more sources
Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis [PDF]
Brain and BehaviorIntroduction Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality globally. Standard antiplatelet therapies, while partially effective, do not fully inhibit all pathways of platelet aggregation, leaving patients at risk of recurrent ...
Abdullah Bin Kamran +9 more
doaj +2 more sources
Effect of Intravenous Tirofiban Versus Placebo on Excellent Outcome in Patients With Acute Ischemic Stroke: The Multicenter, Randomized INSTANT Trial Protocol [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground It is common that symptoms do not improve or even worsen after intravenous thrombolysis (IVT) in acute ischemic stroke. However, it remains unknown whether early administration of tirofiban after IVT may improve clinical outcomes.
Fan Zhang +25 more
doaj +2 more sources
Tirofiban-Induced Profound Thrombocytopenia: A Case Report. [PDF]
CureusPlatelet glycoprotein IIB/IIIA antagonists are potent inhibitors of platelet aggregation. Although the incidence of thrombocytopenia following their administration is relatively low, it can sometimes lead to fatal consequences. We report a case of a 57-year-old gentleman presenting with non-ST elevation myocardial infarction complicated with tirofiban ...
Al Achkar Z +3 more
europepmc +3 more sources
Number of Retrieval Attempts and the Association of Intravenous Tirofiban with Symptomatic Intracranial Hemorrhage in Patients with Successful Endovascular Therapy: Results of the RESCUE BT Trial [PDF]
Clinical Interventions in AgingXiangxiang Peng,1,* Changwei Guo,2,* Jie Yang,2 Shitao Fan,2 Xu Xu,2 Jinfu Ma,2 Zhixi Wang,2 Shihai Yang,2 Wenjie Zi,2 Xianjun Huang,1 Hongjun Wang3 1Department of Neurology, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui Province ...
Peng X +10 more
doaj +2 more sources
Tirofiban-induced thrombocytopenia
Annals of Medicine, 2023 Tirofiban is a small non-peptide ligand-mimetic Glycoprotein (GP) IIb/IIIa inhibitor which can reversibly bind to the arginine-glycine-aspartic acid (RGD) recognition site of GP IIb/IIIa to prevent platelet aggregation. It reduces the incidence of thrombotic cardiovascular events in patients with non-ST-segment elevation acute coronary syndrome (NSTE ...
Jun Wang, Dongna Zou
openaire +3 more sources
Interdisciplinary Neurosurgery, 2022 Objective: We aimed to develop an optimal protocol for failed mechanical thrombectomy (MT) in cases of emergent large vessel occlusion (ELVO) with intracranial atherosclerosis (ICAS).
Yun Ho Noh +11 more
doaj +1 more source
Zhongguo shuxue zazhi, 2022 Objective To explore the feasibility of tirofiban, a platelet surface glycoprotein (GP)Ⅱb/Ⅲa receptor antagonist intervene in transfusion-related acute lung injury (TRALI), by inhibiting platelet activation and by preventing platelet and neutrophil ...
Xin YUAN +6 more
doaj +1 more source
Scientific Reports, 2021 Periprocedural antithrombotic management with glycoprotein IIb/IIIa inhibitors (GPI) for intracranial artery stenting is still controversial. We sought to assess the safety and efficacy of prophylactic tirofiban infusion for acute intracranial ...
Lili Sun +9 more
doaj +1 more source