Results 1 to 10 of about 6,401 (138)

Efficacy and safety of tirofiban injection with intracranial stenting in early reocclusion due to intracranial atherosclerosis

Interdisciplinary Neurosurgery: Advanced Techniques and Case Management, 2022
Objective: We aimed to develop an optimal protocol for failed mechanical thrombectomy (MT) in cases of emergent large vessel occlusion (ELVO) with intracranial atherosclerosis (ICAS).
Seok-Mann Yoon, Jae Sang Oh
exaly   +3 more sources

Tirofiban interferes with antibody-mediated transfusion-related acute lung injury by inhibiting platelet-neutrophil binding

Zhongguo shuxue zazhi, 2022
Objective To explore the feasibility of tirofiban, a platelet surface glycoprotein (GP)Ⅱb/Ⅲa receptor antagonist intervene in transfusion-related acute lung injury (TRALI), by inhibiting platelet activation and by preventing platelet and neutrophil ...
Xin YUAN, Yunhong YU, Congchao QIAO, Pan SUN, Na SU, Peng JIANG, Fangzhao LIN   +6 more
doaj   +1 more source

Safety and efficacy of prophylactic tirofiban infusion for acute intracranial intraprocedural stent thrombosis

Scientific Reports, 2021
Periprocedural antithrombotic management with glycoprotein IIb/IIIa inhibitors (GPI) for intracranial artery stenting is still controversial. We sought to assess the safety and efficacy of prophylactic tirofiban infusion for acute intracranial ...
Lili Sun, Jinping Zhang, Yun Song, Wei Zhao, Meimei Zheng, Jun Zhang, Hao Yin, Wei Wang, Yao Meng, Ju Han   +9 more
doaj   +1 more source

Comparison of the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris in long term follow‐up

Kaohsiung Journal of Medical Sciences, 2021
To investigate the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris (UA).
Li Deng, Hai‐Zhen Jia, Mao‐Chun Li, Wei Zhu   +3 more
doaj   +1 more source

Local tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban ASSIST study

BMC Neurology, 2020
Background Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT).
Yong-Won Kim, Sung-Il Sohn, Joonsang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Dong-Hun Kang, Yong-Sun Kim, Seong-Joon Lee, Ji Man Hong, Jin Wook Choi, Yang-Ha Hwang, Jin Soo Lee   +11 more
doaj   +1 more source

Can Tirofiban Improve the Outcome of Patients With Acute Ischemic Stroke: A Propensity Score Matching Analysis

Frontiers in Neurology, 2021
Objective: To evaluate the efficacy and safety of tirofiban for patients with acute ischemic stroke (AIS), especially posterior circulation stroke (PCS).Methods: We enrolled consecutive patients with AIS who suffered large artery occlusion (LAO) and ...
Lingxin Cai, Xiaobo Yu, Jun Yu, Jing Xu, Liang Xu, Chenhan Ling, Min Lou, Cheng Yu, Cong Qian   +8 more
doaj   +1 more source

Safety and Efficacy of Low-Dose Tirofiban Combined With Intravenous Thrombolysis and Mechanical Thrombectomy in Acute Ischemic Stroke: A Matched-Control Analysis From a Nationwide Registry

Frontiers in Neurology, 2021
Purpose: Tirofiban administration to acute ischemic stroke patients undergoing mechanical thrombectomy with preceding intravenous thrombolysis remains controversial.
Gaoting Ma, Shuo Li, Baixue Jia, Dapeng Mo, Ning Ma, Feng Gao, Xiaochuan Huo, Gang Luo, Anxin Wang, Yuesong Pan, Ligang Song, Xuan Sun, Xuelei Zhang, Liqiang Gui, Cunfeng Song, Ya Peng, Jin Wu, Shijun Zhao, Junfeng Zhao, Zhiming Zhou, Zhongrong Miao   +20 more
doaj   +1 more source

Efficacy and safety of tirofiban in patients with acute ischemic stroke without large-vessel occlusion and not receiving intravenous thrombolysis: A randomized controlled open-label trial

Journal of Neurorestoratology, 2022
ObjectiveTo investigate the effectiveness and safety of tirofiban in patients with acute ischemic stroke (AIS) without large-vessel occlusions and not receiving intravenous thrombolysis.MethodsOverall, 267 cases were included in the study (134 cases in ...
Yongpeng Yu, Yali Zheng, Xia Dong, Xiaohong Qiao, Yu Tao   +4 more
doaj   +1 more source

Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation

Platelets, 2022
We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry.
Martina Aguiar Bucsai, Christian Idel, Barbara Wollenberg, Christine Mannhalter, Admar Verschoor   +4 more
doaj   +1 more source

Platelet Function and Risk of Bleeding in Patients With Acute Coronary Syndrome Following Tirofiban Infusion

Frontiers in Pharmacology, 2019
Aim: To assess platelet (PLT) function and bleeding risks in patients with acute coronary syndrome after tirofiban infusion.Methods: Patients diagnosed with acute coronary syndrome from May 2016 to February 2018 in the Department of Cardiac Intensive ...
Xiaoye Li, Shuning Zhang, Zi Wang, Qiuyi Ji, Qibing Wang, Xiaoyu Li, Qianzhou Lv   +6 more
doaj   +1 more source