Results 1 to 10 of about 6,234 (155)

Efficacy and Safety of Tirofiban for the Management of Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials (RCTs) [PDF]

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
Graphical representation of the comparative efficacy and safety of intravenous tirofiban for acute ischemic stroke in randomized controlled trials. ABSTRACT Background: Tirofiban is a GP IIb/IIIa inhibitor, an anti‐platelet drug that is used in ischemic stroke or acute coronary syndromes.
Dorothy Lim Bullecer   +12 more
wiley   +2 more sources

Tirofiban‐Associated Profound Thrombocytopenia in a Patient With Glucose‐6‐Phosphate Dehydrogenase Deficiency Undergoing Primary Percutaneous Coronary Intervention: A Case Report [PDF]

open access: yesCase Reports in Cardiology, Volume 2026, Issue 1, 2026.
Background Profound thrombocytopenia after tirofiban exposure during primary percutaneous coronary intervention (PCI) is rare but clinically important. Causal attribution may be challenging when unfractionated heparin is coadministered, and the relevance of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency remains uncertain.
Chuanwei Zhao   +6 more
wiley   +2 more sources

Efficacy of simultaneous infusion of tirofiban with intravenous thrombolysis in patients with acute anterior choroidal or paramedian pontine infarction: TITACIPPI study [PDF]

open access: yesFrontiers in Neurology
Background and purposeIntravenous thrombolysis combined with tirofiban (IVT plus tirofiban) has been reported to be more effective than IVT alone in preventing early neurological deterioration (END) and improving 3-month functional outcomes in patients ...
Moussa Toudou-Daouda   +14 more
doaj   +2 more sources

Efficacy and safety of tirofiban injection with intracranial stenting in early reocclusion due to intracranial atherosclerosis

open access: yesInterdisciplinary Neurosurgery, 2022
Objective: We aimed to develop an optimal protocol for failed mechanical thrombectomy (MT) in cases of emergent large vessel occlusion (ELVO) with intracranial atherosclerosis (ICAS).
Yun Ho Noh   +11 more
doaj   +1 more source

Tirofiban interferes with antibody-mediated transfusion-related acute lung injury by inhibiting platelet-neutrophil binding

open access: yesZhongguo shuxue zazhi, 2022
Objective To explore the feasibility of tirofiban, a platelet surface glycoprotein (GP)Ⅱb/Ⅲa receptor antagonist intervene in transfusion-related acute lung injury (TRALI), by inhibiting platelet activation and by preventing platelet and neutrophil ...
Xin YUAN   +6 more
doaj   +1 more source

Safety and efficacy of prophylactic tirofiban infusion for acute intracranial intraprocedural stent thrombosis

open access: yesScientific Reports, 2021
Periprocedural antithrombotic management with glycoprotein IIb/IIIa inhibitors (GPI) for intracranial artery stenting is still controversial. We sought to assess the safety and efficacy of prophylactic tirofiban infusion for acute intracranial ...
Lili Sun   +9 more
doaj   +1 more source

Comparison of the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris in long term follow‐up

open access: yesKaohsiung Journal of Medical Sciences, 2021
To investigate the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris (UA).
Li Deng   +3 more
doaj   +1 more source

Local tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban ASSIST study

open access: yesBMC Neurology, 2020
Background Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT).
Yong-Won Kim   +11 more
doaj   +1 more source

Can Tirofiban Improve the Outcome of Patients With Acute Ischemic Stroke: A Propensity Score Matching Analysis

open access: yesFrontiers in Neurology, 2021
Objective: To evaluate the efficacy and safety of tirofiban for patients with acute ischemic stroke (AIS), especially posterior circulation stroke (PCS).Methods: We enrolled consecutive patients with AIS who suffered large artery occlusion (LAO) and ...
Lingxin Cai   +8 more
doaj   +1 more source

Safety and Efficacy of Low-Dose Tirofiban Combined With Intravenous Thrombolysis and Mechanical Thrombectomy in Acute Ischemic Stroke: A Matched-Control Analysis From a Nationwide Registry

open access: yesFrontiers in Neurology, 2021
Purpose: Tirofiban administration to acute ischemic stroke patients undergoing mechanical thrombectomy with preceding intravenous thrombolysis remains controversial.
Gaoting Ma   +20 more
doaj   +1 more source

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