Results 1 to 10 of about 9,195 (234)

Tirofiban combined with Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY): protocol for a multicentre, randomised controlled trial [PDF]

Stroke and Vascular Neurology, 2023
Background Perforating artery territorial infarction (PAI) caused by branch atheromatous disease (BAD) is prone to recurrence and early progression without an effective and well-documented antiplatelet treatment regimen.
Liping Liu, Yongjun Wang, Yilong Wang, Xingquan Zhao, Xiaoling Liao, Weiqi Chen, Yuesong Pan, Hui Qu, Shuo Feng, Yicong Wang   +9 more
doaj   +3 more sources

Subtyping treatment response of tirofiban in acute ischemic stroke based on neuroimaging features [PDF]

Clinical and Translational Science, 2023
In a previously published clinical trial, we demonstrated that tirofiban was effective and safe in acute ischemic stroke (AIS) patients who did not undergo early recanalization treatments.
Bin Han, Xu Man, Jian Ding, Yuzhu Li, Xintao Tian, Xuelian Zhu, Jiang Yu, Jinping Sun   +7 more
doaj   +3 more sources

The impact of intraarterial, intravenous, and combined tirofiban on endovascular treatment for acute intracranial atherosclerotic occlusion [PDF]

Frontiers in Neurology
Background and purposeAdjunctive tirofiban administration in patients undergoing endovascular treatment (EVT) for acute large vessel occlusion (LVO) has been investigated in several studies. However, the findings are conflict. This study aimed to compare
Zhiping Bu, Dapeng Sun, Gaoting Ma, Baixue Jia, Xu Tong, Xiaochuan Huo, Anxin Wang, Ning Ma, Feng Gao, Dapeng Mo, Ligang Song, Xuan Sun, Yiming Deng, Xiaoqing Li, Bo Wang, Gang Luo, Deguo Su, Zhongrong Miao   +17 more
doaj   +3 more sources

Adjunct Intraarterial or Intravenous Tirofiban Versus No Tirofiban After Successful Recanalization of Basilar Artery Occlusion Stroke: The BASILAR Registry [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Approximately half of patients who achieve successful reperfusion do not achieve functional independence. The present study sought to investigate the clinical outcomes and safety of intraarterial or intravenous tirofiban as adjunct therapy in ...
Huagang Li, Dongsheng Ju, Zhaojun Tao, Jiayin Wang, Thanh N. Nguyen, Jeffrey L. Saver, Raul G. Nogueira, Chang Liu, Qingwu Yang, Zhongming Qiu, Congguo Yin, Dong Sun, Shudong Liu   +12 more
doaj   +3 more sources

The safety and efficacy of intra-arterial low-dose tirofiban administration during endovascular therapy in patients with large ischemic core volume [PDF]

Scientific Reports
This study aimed to evaluate the safety and efficacy of intra-arterial (IA) administration of low- dose tirofiban during endovascular therapy in patients with large ischemic core volumes on initial brain CT. Patients were divided into two groups based on
Kwang-Chun Cho, Nak-Hoon Son, So Hyeon Gwon, Jin Wook Choi, Woo Sang Jung   +4 more
doaj   +3 more sources

Cost-effectiveness of tirofiban for acute ischemic stroke without large or medium-sized vessel occlusion: A Markov modelling analysis from the Chinese and United States perspectives. [PDF]

PLoS ONE
BackgroundThe RESCUE BT2 trial recently showcased the efficacy of tirofiban in treating acute ischemic stroke (AIS) without large or medium-sized vessel occlusion.
Li Wang, Yuhong Zeng, Limei Zhou, Ping Xu, Xianbin Guo, Yu Xie, Junxiu Cai, Min Pan, Jie Tang, Qingtao Gong, Rong Su, Yan Liu, Yake Lou   +12 more
doaj   +3 more sources

Influence of tirofiban on stroke outcome after mechanical thrombectomy in acute vertebrobasilar artery occlusion

BMC Neurology, 2022
Background Even undergoing mechanical thrombectomy (MT), patients with acute vertebrobasilar artery occlusion (AVBAO) still have a high rate of mortality.
Xiding Pan, Mengyi Xu, Yuxiang Fei, Shiteng Lin, Yapeng Lin, Jianjun Zou, Jie Yang   +6 more
doaj   +2 more sources

Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model [PDF]

Nature Communications
Venous thrombosis (VT) is a common vascular disease associated with reduced survival and a high recurrence rate. VT is initiated by the accumulation of platelets and neutrophils at sites of endothelial cell activation. A role for platelet αIIbβ3 in VT is
Brian D. Adair, Conroy O. Field, José L. Alonso, Jian-Ping Xiong, Shi-Xian Deng, Hyun Sook Ahn, Eivgeni Mashin, Clary B. Clish, Johannes van Agthoven, Mark Yeager, Youzhong Guo, David A. Tess, Donald W. Landry, Mortimer Poncz, M. Amin Arnaout   +14 more
doaj   +2 more sources

Association of tirofiban treatment with outcomes following endovascular therapy in cardioembolic stroke: insights from the RESCUE BT randomized trial

European Journal of Medical Research, 2023
Background and purpose The efficacy and safety of tirofiban in endovascular therapy for cardioembolic ischemic stroke patients remain controversial.
Benbing Rong, Zhangbao Guo, Lijie Gao, Yuan Yang, Wenjie Zi, Zhongming Qiu, Fengli Li, Zhiyu Lv, Ying luo, Renliang Meng, Yang Xie, Ting Long, Shujiang Zhang, Jinshan Jiang, Jinfeng Tian, Jingling Zhao, Hongliang Zeng, Zhengzhou Yuan   +17 more
doaj   +2 more sources

The efficacy and safety of continuous intravenous tirofiban for acute ischemic stroke patients treated by endovascular therapy: a meta-analysis. [PDF]

Front Neurol
Introduction Tirofiban is a non-peptide selective glycoprotein IIb/IIIa receptor inhibitor with a short half-life. The research assesses the efficacy and safety of continuous intravenous tirofiban in patients with acute ischemic stroke (AIS) undergoing ...
Wang M, Li J, Zhang L, Li N, Li X, Wang P.   +5 more
europepmc   +2 more sources