Results 1 to 10 of about 6,300 (191)

Local tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban ASSIST study [PDF]

BMC Neurology, 2020
Background Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT).
Yong-Won Kim, Sung-Il Sohn, Joonsang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Dong-Hun Kang, Yong-Sun Kim, Seong-Joon Lee, Ji Man Hong, Jin Wook Choi, Yang-Ha Hwang, Jin Soo Lee   +11 more
doaj   +4 more sources

Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis [PDF]

Brain and Behavior
Introduction Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality globally. Standard antiplatelet therapies, while partially effective, do not fully inhibit all pathways of platelet aggregation, leaving patients at risk of recurrent ...
Abdullah Bin Kamran, Ahmed Bazil Bin Khalil, Ayesha Muhammad, Hira Arshad, Fatima Nazir, Muhammad Mateen Ali, M. Mairaj Umar, Muhammad Farhan, Sudhair Alam, Javed Iqbal   +9 more
doaj   +2 more sources

Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model [PDF]

Nature Communications
Venous thrombosis (VT) is a common vascular disease associated with reduced survival and a high recurrence rate. VT is initiated by the accumulation of platelets and neutrophils at sites of endothelial cell activation. A role for platelet αIIbβ3 in VT is
Brian D. Adair, Conroy O. Field, José L. Alonso, Jian-Ping Xiong, Shi-Xian Deng, Hyun Sook Ahn, Eivgeni Mashin, Clary B. Clish, Johannes van Agthoven, Mark Yeager, Youzhong Guo, David A. Tess, Donald W. Landry, Mortimer Poncz, M. Amin Arnaout   +14 more
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Number of Retrieval Attempts and the Association of Intravenous Tirofiban with Symptomatic Intracranial Hemorrhage in Patients with Successful Endovascular Therapy: Results of the RESCUE BT Trial [PDF]

Clinical Interventions in Aging
Xiangxiang Peng,1,* Changwei Guo,2,* Jie Yang,2 Shitao Fan,2 Xu Xu,2 Jinfu Ma,2 Zhixi Wang,2 Shihai Yang,2 Wenjie Zi,2 Xianjun Huang,1 Hongjun Wang3 1Department of Neurology, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui Province ...
Peng X, Guo C, Yang J, Fan S, Xu X, Ma J, Wang Z, Yang S, Zi W, Huang X, Wang H   +10 more
doaj   +2 more sources

Effect of Intravenous Tirofiban Versus Placebo on First‐Pass Successful Reperfusion in Endovascular Stroke Thrombectomy: Insights From the RESCUE BT Randomized Clinical Trial [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background First‐pass successful reperfusion (FPSR), defined as a successful/complete reperfusion achieved after a single thrombectomy pass, is predictive of favorable outcome in patients with acute ischemic stroke with large‐vessel occlusion.
Junjie Yuan, Hanming Ge, Zhaojun Tao, Huijie An, Qin Han, Jeffrey L. Saver, Thanh N. Nguyen, Simin Zhou, An Mao, Yuelu Wu, Raul Gomes Nogueira, Yaxuan Sun, Shunfu Jiang, Liping Wei, Xinmin Fu, Yongjie Bai, Shunyu Yang, Wei Hu, Guling Zhang, Chengde Pan, Shuai Zhang, Lin Qiao, Qiong Chen, Hongfei Sang, Zhongming Qiu, Fengfu Wu, Mingze Chang, Zhongfan Ruan   +27 more
doaj   +2 more sources

Safety and efficacy of prophylactic tirofiban infusion for acute intracranial intraprocedural stent thrombosis

Scientific Reports, 2021
Periprocedural antithrombotic management with glycoprotein IIb/IIIa inhibitors (GPI) for intracranial artery stenting is still controversial. We sought to assess the safety and efficacy of prophylactic tirofiban infusion for acute intracranial ...
Lili Sun, Jinping Zhang, Yun Song, Wei Zhao, Meimei Zheng, Jun Zhang, Hao Yin, Wei Wang, Yao Meng, Ju Han   +9 more
doaj   +1 more source

Tirofiban interferes with antibody-mediated transfusion-related acute lung injury by inhibiting platelet-neutrophil binding

Zhongguo shuxue zazhi, 2022
Objective To explore the feasibility of tirofiban, a platelet surface glycoprotein (GP)Ⅱb/Ⅲa receptor antagonist intervene in transfusion-related acute lung injury (TRALI), by inhibiting platelet activation and by preventing platelet and neutrophil ...
Xin YUAN, Yunhong YU, Congchao QIAO, Pan SUN, Na SU, Peng JIANG, Fangzhao LIN   +6 more
doaj   +1 more source

Comparison of the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris in long term follow‐up

Kaohsiung Journal of Medical Sciences, 2021
To investigate the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris (UA).
Li Deng, Hai‐Zhen Jia, Mao‐Chun Li, Wei Zhu   +3 more
doaj   +1 more source

Can Tirofiban Improve the Outcome of Patients With Acute Ischemic Stroke: A Propensity Score Matching Analysis

Frontiers in Neurology, 2021
Objective: To evaluate the efficacy and safety of tirofiban for patients with acute ischemic stroke (AIS), especially posterior circulation stroke (PCS).Methods: We enrolled consecutive patients with AIS who suffered large artery occlusion (LAO) and ...
Lingxin Cai, Xiaobo Yu, Jun Yu, Jing Xu, Liang Xu, Chenhan Ling, Min Lou, Cheng Yu, Cong Qian   +8 more
doaj   +1 more source

Safety and Efficacy of Low-Dose Tirofiban Combined With Intravenous Thrombolysis and Mechanical Thrombectomy in Acute Ischemic Stroke: A Matched-Control Analysis From a Nationwide Registry

Frontiers in Neurology, 2021
Purpose: Tirofiban administration to acute ischemic stroke patients undergoing mechanical thrombectomy with preceding intravenous thrombolysis remains controversial.
Gaoting Ma, Shuo Li, Baixue Jia, Dapeng Mo, Ning Ma, Feng Gao, Xiaochuan Huo, Gang Luo, Anxin Wang, Yuesong Pan, Ligang Song, Xuan Sun, Xuelei Zhang, Liqiang Gui, Cunfeng Song, Ya Peng, Jin Wu, Shijun Zhao, Junfeng Zhao, Zhiming Zhou, Zhongrong Miao   +20 more
doaj   +1 more source