Tirofiban Combination Therapy for Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis [PDF]
Brain and BehaviorIntroduction Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality globally. Standard antiplatelet therapies, while partially effective, do not fully inhibit all pathways of platelet aggregation, leaving patients at risk of recurrent ...
Abdullah Bin Kamran +9 more
doaj +5 more sources
Safety and efficacy of prophylactic tirofiban infusion for acute intracranial intraprocedural stent thrombosis [PDF]
Scientific Reports, 2021 Periprocedural antithrombotic management with glycoprotein IIb/IIIa inhibitors (GPI) for intracranial artery stenting is still controversial. We sought to assess the safety and efficacy of prophylactic tirofiban infusion for acute intracranial ...
Lili Sun +9 more
doaj +2 more sources
Influence of tirofiban on stroke outcome after mechanical thrombectomy in acute vertebrobasilar artery occlusion [PDF]
BMC Neurology, 2022 Background Even undergoing mechanical thrombectomy (MT), patients with acute vertebrobasilar artery occlusion (AVBAO) still have a high rate of mortality.
Xiding Pan +6 more
doaj +2 more sources
Effects of Periprocedural Tirofiban vs. Oral Antiplatelet Drug Therapy on Posterior Circulation Infarction in Patients With Acute Intracranial Atherosclerosis-Related Vertebrobasilar Artery Occlusion [PDF]
Frontiers in Neurology, 2020 Background and purpose: Tirofiban and oral antiplatelet drugs can be used to inhibit reocclusion and restore microvascular reperfusion during endovascular treatment (EVT).
Xuan Sun +5 more
doaj +2 more sources
Tirofiban-induced acute profound thrombocytopenia in endovascular therapy for acute ischemic stroke: a rare case report [PDF]
BMC NeurologyBackground Studies have shown that tirofiban (a glycoprotein IIb/IIIa receptor antagonist) is effective in the endovascular treatment of cerebrovascular diseases. However, it has also been reported that tirofiban can cause thrombocytopenia.
Jiuling Liu +4 more
doaj +2 more sources
Influence of Tirofiban maintenance duration on patients with acute myocardial infarction treated by percutaneous coronary intervention [PDF]
Chronic Diseases and Translational Medicine, 2015 Objective: To evaluate the efficacy and short term prognosis of Tirofiban in different treatment duration in patients with acute ST segment elevation myocardial infarction (STEMI) and percutaneous coronary intervention (PCI) combined with intracoronary ...
Zhen-Guo Ji +6 more
doaj +2 more sources
Effect of Intravenous Tirofiban Versus Placebo on Excellent Outcome in Patients With Acute Ischemic Stroke: The Multicenter, Randomized INSTANT Trial Protocol [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground It is common that symptoms do not improve or even worsen after intravenous thrombolysis (IVT) in acute ischemic stroke. However, it remains unknown whether early administration of tirofiban after IVT may improve clinical outcomes.
Fan Zhang +25 more
doaj +2 more sources
Mechanical Solitaire Thrombectomy with Low-Dose Booster Tirofiban Injection [PDF]
Neurointervention, 2016 PurposeMechanical thrombectomy using a Solitaire stent has been associated with a high recanalization rate and favorable clinical outcome in intra-arterial thrombolysis.
Duck-Ho Goh +3 more
doaj +3 more sources
Safety of tirofiban and dual antiplatelet therapy in treating intracranial aneurysms
Stroke and Vascular Neurology, 2019 Background Endovascular treatment of intracranial aneurysms usually involves stent-assisted coiling (SAC) and flow diverters. Glycoprotein IIb/IIIa inhibitors such as tirofiban and dual antiplatelet therapy (DAPT) are required to prevent thromboembolic ...
Edgar A Samaniego +2 more
exaly +3 more sources
Efficacy of Tirofiban combined with oral antiplatelet therapy in progressive ischemic stroke: A systematic review and meta-analysis. [PDF]
Exp Ther MedYu Y, Deng T, Jiang Y, Ge J, Li Y.
europepmc +3 more sources