Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast +66 more
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Successful treatment of cardiogenic shock by stenting of the left main coronary artery in acute myocardial infarction [PDF]
Introduction. Patients with non-ST elevation acute coronary syndromes (NSTE-ACS) are sometimes severely hemodynamicly compromised. Urgent coronary angiography should be performed in these patients in percutaneous coronary intervention (PCI) centers ...
Bošković Aneta +4 more
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This study aimed to evaluate the safety and efficacy of intra-arterial (IA) administration of low- dose tirofiban during endovascular therapy in patients with large ischemic core volumes on initial brain CT. Patients were divided into two groups based on
Kwang-Chun Cho +4 more
doaj +1 more source
Successful Recanalization by Catheter-Directed Thrombolysis with a Continuous Intra-arterial Infusion of Low-Dose Tirofiban for Acute Carotid In-Stent Thrombosis [PDF]
Heping Yang, Zhang Guiqiang
openalex +3 more sources
BackgroundThe RESCUE BT2 trial recently showcased the efficacy of tirofiban in treating acute ischemic stroke (AIS) without large or medium-sized vessel occlusion.
Li Wang +12 more
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Combined anatomical and clinical factors for the long-term risk stratification of patients undergoing percutaneous coronary intervention: the Logistic Clinical SYNTAX score [PDF]
Background The SYNTAX score (SXscore), an anatomical-based scoring tool reflecting the complexity of coronary anatomy, has established itself as an important long-term prognostic factor in patients undergoing percutaneous coronary intervention (PCI). The
Dawkins, Keith D. +14 more
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Bivalirudin started during emergency transport for primary PCI. [PDF]
BACKGROUND: Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding and death in patients undergoing primary percutaneous coronary intervention (PCI).
Berg, J. van den +25 more
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Molecular basis for Staphylococcus aureus-mediated platelet aggregate formation under arterial shear in vitro. [PDF]
OBJECTIVE: Staphylococcus aureus is the most frequent causative organism of infective endocarditis (IE) and is characterized by thrombus formation on a cardiac valve that can embolize to a distant site. Previously, we showed that S.
Clarke, Niamh +5 more
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Anti-platelet therapy: ADP receptor antagonists. [PDF]
The P2Y(12) receptor on platelets with which ADP interacts has an important role in promoting platelet function and thereby platelet involvement in both haemostasis and thrombosis.
Heptinstall, S, Wijeyeratne, YD
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Novel strategies for assessing platelet reactivity [PDF]
There are many approaches to assessing platelet reactivity and many uses for such measurements. Initially, measurements were based on the ability of platelets separated from other blood cells to aggregate together following activation with an appropriate
Dovlatova N +10 more
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