Results 21 to 30 of about 12,790 (219)

Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation

Platelets, 2022
We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry.
Martina Aguiar Bucsai, Christian Idel, Barbara Wollenberg, Christine Mannhalter, Admar Verschoor   +4 more
doaj   +1 more source

Efficacy and safety of tirofiban in patients with acute ischemic stroke without large-vessel occlusion and not receiving intravenous thrombolysis: A randomized controlled open-label trial

Journal of Neurorestoratology, 2022
ObjectiveTo investigate the effectiveness and safety of tirofiban in patients with acute ischemic stroke (AIS) without large-vessel occlusions and not receiving intravenous thrombolysis.MethodsOverall, 267 cases were included in the study (134 cases in ...
Yongpeng Yu, Yali Zheng, Xia Dong, Xiaohong Qiao, Yu Tao   +4 more
doaj   +1 more source

Morphine Analgesia Pre-PPCI Is Associated with Prothrombotic State, Reduced Spontaneous Reperfusion and Greater Infarct Size [PDF]

, 2017
Schattauer GmbH Stuttgart.The emergency management of ST-elevation myocardial infarction (STEMI) involves treatment with dual-antiplatelet therapy (DAPT) and primary percutaneous coronary intervention (PPCI). Pain is generally treated with opiates, which
Farag, Mohamed, Gorog, Diana A, Spinthakis, Nikolaos, Srinivasan, Manivannan, Sullivan, Keith, Wellsted, David   +5 more
core   +2 more sources

Elevated Baseline Serum Fibrinogen: Effect on 2-Year Major Adverse Cardiovascular Events Following Percutaneous Coronary Intervention. [PDF]

, 2017
BackgroundElevated fibrinogen is associated with short-term major adverse cardiovascular events (MACE) after percutaneous coronary intervention, but the relation with late MACE is unknown.Methods and resultsBaseline demographics and 2-year MACE were ...
Ang, Lawrence, Behnamfar, Omid, Lin, Felice, Mahmud, Ehtisham, Palakodeti, Samhita, Patel, Mitul P, Pourdjabbar, Ali, Reeves, Ryan R   +7 more
core   +1 more source

Abciximab‐Associated Thrombocytopenia After Previous Tirofiban‐Related Thrombocytopenia [PDF]

, 2006
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90080/1/phco.26.3.423 ...
Dorsch, Michael P., Montague, Debbie, Patterson, Cam, Rodgers, Jo Ellen   +3 more
core   +1 more source

Platelet Function and Risk of Bleeding in Patients With Acute Coronary Syndrome Following Tirofiban Infusion

Frontiers in Pharmacology, 2019
Aim: To assess platelet (PLT) function and bleeding risks in patients with acute coronary syndrome after tirofiban infusion.Methods: Patients diagnosed with acute coronary syndrome from May 2016 to February 2018 in the Department of Cardiac Intensive ...
Xiaoye Li, Shuning Zhang, Zi Wang, Qiuyi Ji, Qibing Wang, Xiaoyu Li, Qianzhou Lv   +6 more
doaj   +1 more source

Glycoprotein IIb/IIIa Inhibitors Use and Outcome after Percutaneous Coronary Intervention for Non-ST Elevation Myocardial Infarction [PDF]

, 2014
Aims. We investigate the effect of glycoprotein IIb/IIIa (GP IIb/IIIa) inhibitors on long-term outcomes following percutaneous coronary intervention (PCI) after non-ST elevation myocardial infarction (NSTEMI). Meta-analyses indicate that these agents are
Antoniou, S, Gallagher, S, Howard, JP, Jones, DA, Knight, C, Mathur, A, Rathod, K, Weerackody, R, Wragg, A, Wright, P   +9 more
core   +4 more sources

Hydration versus N-acetylcysteine for protection of renal function in patients with renal insufficiency undergoing percutaneous coronary intervention [PDF]

, 2003
A Clarion Call for Large-Scale Collaborative Studies of Pediatric Proton ...
Berrington de Gonzalez, Amy, Buchsbaum, Jeffrey C, de Vathaire, Florent, Dörr, Wolfgang, Hass-Kogan, Daphne, Kleinerman, Ruth A, Langendijk, Johannes A, Mahajan, Anita, Newhauser, Wayne, Ottolenghi, Andrea, Ronckers, Cecile, Schulte, Reinhard, Vikram, Bhadrasian, Walsh, Linda, Yock, Torunn I   +14 more
core   +1 more source

Safety and efficacy of low-dose and long-course tirofiban in large hemispheric infarction

Frontiers in Neurology, 2022
BackgroundThe clinical efficacy and safety of tirofiban in the treatment of large hemispheric infarction (LHI) remain controversial.MethodsThis study prospectively enrolled patients with acute LHI who were admitted to Putuo Hospital affiliated with ...
Yinqin Hu, Qian Xiao, Zhizhen Shi, Yangbo Hou, Zhen Chen, Jiwei Cheng, Guoyi Li   +6 more
doaj   +1 more source

Association of tirofiban treatment with outcomes following endovascular therapy in cardioembolic stroke: insights from the RESCUE BT randomized trial

European Journal of Medical Research, 2023
Background and purpose The efficacy and safety of tirofiban in endovascular therapy for cardioembolic ischemic stroke patients remain controversial.
Benbing Rong, Zhangbao Guo, Lijie Gao, Yuan Yang, Wenjie Zi, Zhongming Qiu, Fengli Li, Zhiyu Lv, Ying luo, Renliang Meng, Yang Xie, Ting Long, Shujiang Zhang, Jinshan Jiang, Jinfeng Tian, Jingling Zhao, Hongliang Zeng, Zhengzhou Yuan   +17 more
doaj   +1 more source