Results 31 to 40 of about 6,032 (153)

Safety and Efficacy of Tirofiban in Severe Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

Journal of Cardiovascular Development and Disease, 2022
Tirofiban has recently shown encouraging efficacy and safety among acute ischemic stroke (AIS) patients with mechanical thrombectomy (MT). However, the benefits of tirofiban varied among studies depending on the patient’s condition, which was often not ...
Lingxin Cai, Tingting Wang, Aiqing Chen, Chenhan Ling, Jing Xu, Cong Qian, Gao Chen   +6 more
doaj   +1 more source

The impact of intraarterial, intravenous, and combined tirofiban on endovascular treatment for acute intracranial atherosclerotic occlusion

Frontiers in Neurology
Background and purposeAdjunctive tirofiban administration in patients undergoing endovascular treatment (EVT) for acute large vessel occlusion (LVO) has been investigated in several studies. However, the findings are conflict. This study aimed to compare
Zhiping Bu, Dapeng Sun, Gaoting Ma, Baixue Jia, Xu Tong, Xiaochuan Huo, Anxin Wang, Ning Ma, Feng Gao, Dapeng Mo, Ligang Song, Xuan Sun, Yiming Deng, Xiaoqing Li, Bo Wang, Gang Luo, Deguo Su, Zhongrong Miao   +17 more
doaj   +1 more source

Effects of two different glycoprotein platelet IIb/IIIa inhibitors and the clinical endpoints in patients with intracranial Pipeline flow diverter implant

Journal of Interventional Medicine, 2020
Objective: To compare the antiplatelet effect and major adverse cerebrovascular events of Pipeline for intracranial aneurysms using glycoprotein IIb/IIIa antagonists (GPI) eptifibatide and tirofiban.
Qiao Deng, Shichao Zhang, Mingzhou Li, Guozhong Zhang, Wenfeng Feng   +4 more
doaj   +1 more source

Statistical analysis for efficacy of tirofiban combined with ozagrel in the treatment of progressive cerebral infarction patients out of thrombolytic therapy time window

Clinics, 2021
OBJECTIVES: To investigate the safety and efficacy of combined tirofiban-ozagrel therapy for treating progressive stroke patients out of thrombolytic therapy time window.
Huiying Zhang, Lei Zheng
doaj   +1 more source

Prevention of In‐Stent Restenosis After PCI by Saponin Natural Products: Inhibition of Platelet Activation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Percutaneous coronary intervention (PCI) enables coronary revascularisation and restores haemodynamic stability but also carries risks of delayed complications including in‐stent restenosis (ISR), a chronic progressive disease with endovascular damage after PCI, which compromises the long‐term efficacy of PCI.
Xueli Lei, Chunlei Lv, Yu Zhang, Zhiyu Li, Hao Shen, Li Zhu   +5 more
wiley   +1 more source

Clinical safety and possible efficacy of tirofiban in combination with intravenous thrombolysis by recombinant tissue plasminogen activator for early treatment of capsular warning syndrome (CWS)

Frontiers in Neuroscience, 2022
The purpose of this study was to assess the efficacy and safety of the combination of tirofiban with intravenous thrombolysis (IVT) in treating patients with capsular warning syndrome (CWS) who failed to respond to the treatment of intravenous ...
Yunzhu Liu, Shiyong Li, Dongdong Hao, Zhongping Zhang, Yongxin Yi, Jiayang Fang, Weizhi Lin, Min Zhang   +7 more
doaj   +1 more source

Rapid Glass‐Substrate Digital Light 3D Printing Enables Anatomically Accurate Stroke Patient‐Specific Carotid Artery‐on‐Chips for Personalized Thrombosis Investigation

Advanced Materials, Volume 38, Issue 5, 22 January 2026.
A rapid glass‐substrate 3D microfabrication method creates anatomically accurate carotid artery‐on‐a‐chip models from stroke patient scans in 2 h. These miniaturized devices replicate patient‐specific blood vessel geometry and flow patterns, enabling real‐time imaging of clot formation under controlled injury.
Yunduo Charles Zhao, Zihao Wang, Arian Nasser, Allan Sun, Zhao Wang, Yingqi Zhang, Jianfang Ren, Haimei Zhao, Nicole Alexis Yap, Yinyan Wang, Zhiyong Li, Ken S Butcher, Freda Passam, Timothy Ang, Lining Arnold Ju   +14 more
wiley   +1 more source

Mechanical Solitaire Thrombectomy with Low-Dose Booster Tirofiban Injection [PDF]

Neurointervention, 2016
PurposeMechanical thrombectomy using a Solitaire stent has been associated with a high recanalization rate and favorable clinical outcome in intra-arterial thrombolysis.
Duck-Ho Goh, Sung-Chul Jin, Hae Woong Jeong, Sam Yeol Ha   +3 more
doaj   +1 more source

AIE‐Mediated In Situ Monitoring of Protein Aggregates During Coagulation and Screening of Anticoagulant Agents

Aggregate, Volume 7, Issue 1, January 2026.
The process of screening active monomers via BioSTAS technology. (A) Analyzing the properties and luminescence mechanism of an AIE molecule through density functional theory and MD simulation. (B) The establishment of a screening model, including biosensing and affinity chromatography. (C) Screening and identification of active substances.
Shuxian Zhang, Hui Yuan, Lingling Yang, Xiaoxuan Fan, Keshuai Liu, Rui Mai, Wangyan Zhao, Cheng Liu, Qiang Han, Yongjian Ai, Qionglin Liang, Xueqin Ma, Guoning Chen   +12 more
wiley   +1 more source

Association between tirofiban monotherapy and efficacy and safety in acute ischemic stroke

BMC Neurology, 2021
Background Studies have suggested that glycoprotein IIb/IIIa antagonists such as tirofiban are beneficial for patients with acute coronary syndromes.
Chunrong Tao, Yuyou Zhu, Chao Zhang, Jianlong Song, Tianlong Liu, Xiaodong Yuan, Wenwu Luo, Changchun Chen, Dezhi Liu, Yuanyuan Zhu, Jie Liu, Wei Hu   +11 more
doaj   +1 more source