Results 31 to 40 of about 12,770 (237)

Safety and Efficacy of Tirofiban in Severe Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

Journal of Cardiovascular Development and Disease, 2022
Tirofiban has recently shown encouraging efficacy and safety among acute ischemic stroke (AIS) patients with mechanical thrombectomy (MT). However, the benefits of tirofiban varied among studies depending on the patient’s condition, which was often not ...
Lingxin Cai, Tingting Wang, Aiqing Chen, Chenhan Ling, Jing Xu, Cong Qian, Gao Chen   +6 more
doaj   +1 more source

Priority setting for research in health care: An application of value of information analysis to glycoprotein IIb/IIIa antagonists in non-ST elevation acute coronary syndrome [PDF]

, 2006
The purpose of this study is to explain the rationale for the value of information approach to priority setting for research and to describe the methods intuitively for those familiar with basic decision analytical modeling.
Bojke, L., Claxton, K., Palmer, S., Philips, Z., Sculpher, M.   +4 more
core   +1 more source

The Safety and Efficiency of Tirofiban in Acute Ischemic Stroke Patients Treated with Mechanical Thrombectomy: A Multicenter Retrospective Cohort Study

Biochemistry Research International, 2020
Introduction. Limited comparative studies have reported the safety and efficacy of tirofiban in acute ischemic stroke (AIS) patients after mechanical thrombectomy (MT).
Lili Zhao, Yating Jian, Tao Li, Heying Wang, Zhang Lei, Man Sun, Ye Li, Yiheng Zhang, Meijuan Dang, Wang Huqing, Sun Hong, Zhang Ru, Hongxing Zhang, Yi Jia, Luo Guogang, Zhang Guilian   +15 more
doaj   +1 more source

A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins [PDF]

, 2017
Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation.
Cavalcanti-Adam, Elisabetta Ada, Geiger, Benjamin, Kapp, Tobias G., Kessler, Horst, Maltsev, Oleg V., Mas Moruno, Carlos, Neubauer, Stefanie, Notni, Johannes, Rechenmacher, Florian, Reuning, Ute, Spatz, Joachim, Wester, Hans-Jürgen, Zarka, Revital   +12 more
core   +2 more sources

Tirofiban on First-Pass Recanalization in Acute Stroke Endovascular Thrombectomy: The OPTIMISTIC Randomized Clinical Trial. [PDF]

JAMA Netw Open
Lin L, Liu F, Yi T, Zhu Y, Yang J, Zhao Y, Wang F, Xiang G, Chen C, Xiao Y, Shen H, Xu L, Long Y, Zhang Y, Huang Z, Chen C, Churilov L, Parsons MW, Chen W, Li G, OPTIMISTIC Investigators.   +20 more
europepmc   +2 more sources

Tirofiban in Acute Ischemic Stroke: Mechanistic Rationale, Clinical Advances, and Emerging Therapeutic Strategies. [PDF]

Drugs
Jiang Y, Huang W, Zhang Y, Ji Q.
europepmc   +3 more sources

Integrins as therapeutic targets: lessons and opportunities. [PDF]

, 2010
The integrins are a large family of cell adhesion molecules that are essential for the regulation of cell growth and function. The identification of key roles for integrins in a diverse range of diseases, including cancer, infection, thrombosis and ...
A Artoni, A Carter, A Etzioni, A Kato, A Loughman, A McDowall, A Qu, A Robinson, A Salas, AD Ricart, AJ Ablooglu, AL Muranyi, AM Weljie, AR Reynolds, AW Partridge, B Furie, BG Feagan, BG Petrich, BP Feuston, BS Coller, C Delbaldo, C Kummer, C Kummer, C Leonardi, C Lu, C Ng, C Rosano, C Warnke, C Xie, CH Polman, CJ Avraamides, CL Leonardi, CL Tofteng, CS Tan, CS Yoon, D Chua, D Cox, D Cox, D Larkin, D Potin, DA Calderwood, DA Calderwood, DA Chudakova, DA Reardon, Dermot Cox, DJ White, DP Chew, DR Phillips, DS Dodd, DS Harburger, E Bernard, E Havrdova, E Manevich, E Ruoslahti, EO Major, FC Gushiken, FE Fleming, G Weitz-Schmidt, GA Caputo, GM D'Abaco, GPA Rice, H Jin, H Yin, H Zhang, H-J Lee, I Ahrens, J Bennett, J Kallen, J Kalra, J Lim, J Morova, J Takagi, J Takagi, J Tamkun, JA Askari, JA Nemeth, JC O'Shea, JE Frampton, JE Smith-Garvin, JP Ortonne, JP Xiong, JP Xiong, JR Fitzgerald, JR Fitzgerald, JR Morgan, JW Tilley, K Aylward, K Peter, K Peter, K Welzenbach, K Yao, K Yuki, KB Gordon, KB Reddy, KL Graham, KL Graham, KL Schornberg, KL Wegener, KR Legate, KV Vijayan, L Dubertret, L Steinman, L Xudong, LM Kenny, M Brennan, M Champe, M Egbertson, M Kim, M Lebwohl, M Martchenko, M Moser, M Raab, M Rosenthal, M Shimaoka, M Shimaoka, M Shimaoka, M Shimaoka, MA Arnaout, Marian Brennan, MC Joseph, ME Cianfrocca, MG Murphy, MN Younes, MP Bonaca, MP Brennan, MP Crump, N Laurens, Niamh Moran, NS Nicholson, O Vinogradova, O Vinogradova, P Hersey, P Koistinen, PA Calabresi, PC McDonald, PE Hughes, PL Stewart, QY Liu, R Anders, R Axelsson, R Blue, R Curtin, R Evans, R Gonzalez-Amaro, R Pytela, R Silva, R Stragies, R Stupp, RA Rudick, RH Aster, RJ Davenport, RJ Davenport, RM Scarborough, RO Hynes, RP Dassanayake, S Honda, S Honda, S Kim, S Kim, S Li, S Liu, S Moschos, S O'Neill, S Wattanasin, SH Watterson, SJ Hyduk, SJ Monkley, SJ Moschos, SJ Shattil, SM Keating, SM Weis, SR Barthel, SR Targan, T Dileepan, T Kwok, T Weller, T Xiao, TA Kelly, TA Yednock, TC Sroka, TE O'Toole, TE Spencer, TJ MacDonald, TM Brophy, TR Gadek, UP Naik, VA Umans, W Humphrey, W Jia, W Neidhart, W Wang, W Yang, X Sewald, Y Aga, Y Funahashi, Y Gong, Y Li, Y Wang, YF Li, YQ Ma   +199 more
core   +1 more source

The impact of intraarterial, intravenous, and combined tirofiban on endovascular treatment for acute intracranial atherosclerotic occlusion

Frontiers in Neurology
Background and purposeAdjunctive tirofiban administration in patients undergoing endovascular treatment (EVT) for acute large vessel occlusion (LVO) has been investigated in several studies. However, the findings are conflict. This study aimed to compare
Zhiping Bu, Dapeng Sun, Gaoting Ma, Baixue Jia, Xu Tong, Xiaochuan Huo, Anxin Wang, Ning Ma, Feng Gao, Dapeng Mo, Ligang Song, Xuan Sun, Yiming Deng, Xiaoqing Li, Bo Wang, Gang Luo, Deguo Su, Zhongrong Miao   +17 more
doaj   +1 more source

Newer agents in antiplatelet therapy: a review. [PDF]

, 2012
Antiplatelet therapy remains the mainstay in preventing aberrant platelet activation in pathophysiological conditions such as myocardial infarction, ischemia, and stroke.
Holinstat, Michael, Yeung, Jennifer
core   +3 more sources

Effects of two different glycoprotein platelet IIb/IIIa inhibitors and the clinical endpoints in patients with intracranial Pipeline flow diverter implant

Journal of Interventional Medicine, 2020
Objective: To compare the antiplatelet effect and major adverse cerebrovascular events of Pipeline for intracranial aneurysms using glycoprotein IIb/IIIa antagonists (GPI) eptifibatide and tirofiban.
Qiao Deng, Shichao Zhang, Mingzhou Li, Guozhong Zhang, Wenfeng Feng   +4 more
doaj   +1 more source