Results 41 to 50 of about 6,111 (204)

Diagnosis and treatment recommendations and case study of severe thrombocytopenia caused by tirofiban

Zhongguo shuxue zazhi, 2023
Objective To investigate the clinical manifestations, diagnosis, differential diagnosis and management strategies of thrombocytopenia caused by tirofiban.
Xiaohui LIU, Cuihua TAO
doaj   +1 more source

Understanding Drug Interactions in Antiplatelet Therapy for Atherosclerotic Vascular Disease: A Systematic Review

CNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
Antiplatelet drugs are essential for treating atherosclerotic vascular disease (ASVD), but drug interactions can lead to resistance and affect therapeutic efficacy. Due to the complexity of treatments in ASVD patients, understanding these interactions is critical for optimizing therapy and reducing adverse effects.
Xiangqian Huang, Jiahao Song, Xiaoming Zhang, Mengqi Wang, Yuchuan Ding, Xunming Ji, Da Zhou, Ran Meng   +7 more
wiley   +1 more source

Emergency Admission Plasma D‐Dimer and Prothrombin Activity: Novel Predictors for Clinical Outcomes After Thrombectomy in Acute Ischemic Stroke With Large Artery Occlusion

CNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
Preoperative high D‐dimer but low PTA level were the independent predictors of 3 months' unfavorable prognosis for AIS‐LVO after calibration of confounders. Elevated admission D‐dimer (≥ 715 mg/L) and reduced PTA levels (< 85.5%) are independent predictors of poor prognosis for patients with AIS‐LVO, and there is a synergistic interaction between the ...
Shandong Jiang, Peizheng Guo, Linxin Cai, Cong Qian, Jun Yu, Liang Xu, Xu Li, Xianyi Chen, Fang Bing, Yuan Yuan, Zhongju Tan, Jing Xu, Jianru Li   +12 more
wiley   +1 more source

SAFETY OF TIROFIBAN FOR PATIENTS WITH ACUTE ISCHEMIC STROKE IN ROUTINE CLINICAL PRACTICE

Российский кардиологический журнал, 2014
Aim. This work aims to study the safety of tirofiban alone and in combination with various treatments in acute ischemic stroke (AIS).Material and methods. 120 AIS patients were included in this study.
Yan-Jun Zhang, Qing Liu, Qin Zhan, Qiong Li   +3 more
doaj   +1 more source

Efficacy and Safety of Tirofiban in Clinical Patients With Acute Ischemic Stroke

Frontiers in Neurology, 2022
BackgroundIntravenous thrombolysis and endovascular thrombectomy have been approved for acute ischemic stroke (AIS). However, only a minority of patients received these treatments in China.
Bin Han, Teng Ma, Zhendong Liu, Yiqun Wu, Weiwei Tan, Shaoyang Sun, Xuemei Li, Changyan Shao, Duyong Tang, Jinping Sun, Jinping Sun, Jinping Sun   +11 more
doaj   +1 more source

Endovascular Treatment of Mirror Aneurysms in Subarachnoid Hemorrhage Patients: Single Stage or Multiple Stage?

Brain and Behavior, Volume 15, Issue 1, January 2025.
This study eaxmined the effectiveness and safetybetween single‐stage and multi‐stage endovascular treatment in subarachnoid haemorrhage patients with mirror aneurysms over the 2‐year follow‐up. In terms of complication rate and MRS score, there was no difference between single and multiple intravascular treatment of mirror intracranial aneurysms in ...
Yunfei Song, Guoqiang Song, Guijing Liu, Limei Mao, Xiuhu An, Chao Peng, Jian Li, Yan Chen, Hongwen Li, Changkai Hou, Bangyue Wang, Yan Zhao, Xiangdong Wang, Gangfeng Yin, Xinyu Yang   +14 more
wiley   +1 more source

Safety and Efficacy of Tirofiban During Mechanical Thrombectomy for Stroke Patients with Preceding Intravenous Thrombolysis

Clinical Interventions in Aging, 2020
Xiaochuan Huo,1,2,* Ming Yang,1,2,* Ning Ma,1,2 Feng Gao,1,2 Dapeng Mo,1,2 Xiaoqing Li,1,2 Anxin Wang,2,3 Yongjun Wang,2,3 Zhongrong Miao1,2 1Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, Beijing ...
Huo X, Yang M, Ma N, Gao F, Mo D, Li X, Wang A, Wang Y, Miao Z   +8 more
doaj  

Aspirin, but Not Tirofiban Displays Protective Effects in Endotoxin Induced Lung Injury. [PDF]

PLoS ONE, 2016
BACKGROUND:Treatment of acute lung injury (ALI) remains an unsolved problem in intensive care medicine. Recruitment of neutrophils into the lungs, regarded as a key mechanism in progression of ALI, depends on signaling between neutrophils and platelets ...
Jessica Tilgner, Klaus Thilo von Trotha, Alexander Gombert, Michael J Jacobs, Maik Drechsler, Yvonne Döring, Oliver Soehnlein, Jochen Grommes   +7 more
doaj   +1 more source

Case report: reuse of tirofiban leads to very severe thrombocytopenia

Frontiers in Cardiovascular Medicine, 2023
BackgroundTelofiban is a class of small molecule non-peptide tyrosine derivatives containing RGD sequences. It is the only platelet surface glycoprotein (GP) IIb/IIIa receptor antagonist (GPI) currently marketed in China.
Yuqing Li, Jiuchun Qiu, Yi Gao, Guangping Li   +3 more
doaj   +1 more source

Targeting noncoding RNAs to treat atherosclerosis

British Journal of Pharmacology, Volume 182, Issue 2, Page 220-245, January 2025.
Noncoding RNAs (ncRNAs) are pivotal for various pathological processes, impacting disease progression. The potential for leveraging ncRNAs to prevent or treat atherosclerosis and associated cardiovascular diseases is of great significance, especially given the increasing prevalence of atherosclerosis in an ageing and sedentary population.
Miron Sopić, Sandra Vladimirov, Jelena Munjas, Tijana Mitić, Ignacio Fernando Hall, Amela Jusic, Dusan Ruzic, Yvan Devaux, On behalf of AtheroNET COST Action CA21153 (https://atheronet.eu/)   +8 more
wiley   +1 more source