Results 41 to 50 of about 12,770 (237)

Statistical analysis for efficacy of tirofiban combined with ozagrel in the treatment of progressive cerebral infarction patients out of thrombolytic therapy time window

Clinics, 2021
OBJECTIVES: To investigate the safety and efficacy of combined tirofiban-ozagrel therapy for treating progressive stroke patients out of thrombolytic therapy time window.
Huiying Zhang, Lei Zheng
doaj   +1 more source

Bivalirudin versus unfractionated heparin: a meta-analysis of patients receiving percutaneous coronary intervention for acute coronary syndromes [PDF]

, 2015
OBJECTIVE: Acute coronary syndrome (ACS) encompasses ST segment elevation myocardial infarction (STEMI), with generally high thrombus burden and non-ST segment elevation ACS (NSTE-ACS), with lower thrombus burden.
Farag, M, Gorog, DA, Prasad, A, Srinivasan, M   +3 more
core   +1 more source

Clinical safety and possible efficacy of tirofiban in combination with intravenous thrombolysis by recombinant tissue plasminogen activator for early treatment of capsular warning syndrome (CWS)

Frontiers in Neuroscience, 2022
The purpose of this study was to assess the efficacy and safety of the combination of tirofiban with intravenous thrombolysis (IVT) in treating patients with capsular warning syndrome (CWS) who failed to respond to the treatment of intravenous ...
Yunzhu Liu, Shiyong Li, Dongdong Hao, Zhongping Zhang, Yongxin Yi, Jiayang Fang, Weizhi Lin, Min Zhang   +7 more
doaj   +1 more source

AIE‐Mediated In Situ Monitoring of Protein Aggregates During Coagulation and Screening of Anticoagulant Agents

Aggregate, Volume 7, Issue 1, January 2026.
The process of screening active monomers via BioSTAS technology. (A) Analyzing the properties and luminescence mechanism of an AIE molecule through density functional theory and MD simulation. (B) The establishment of a screening model, including biosensing and affinity chromatography. (C) Screening and identification of active substances.
Shuxian Zhang, Hui Yuan, Lingling Yang, Xiaoxuan Fan, Keshuai Liu, Rui Mai, Wangyan Zhao, Cheng Liu, Qiang Han, Yongjian Ai, Qionglin Liang, Xueqin Ma, Guoning Chen   +12 more
wiley   +1 more source

Association between tirofiban monotherapy and efficacy and safety in acute ischemic stroke

BMC Neurology, 2021
Background Studies have suggested that glycoprotein IIb/IIIa antagonists such as tirofiban are beneficial for patients with acute coronary syndromes.
Chunrong Tao, Yuyou Zhu, Chao Zhang, Jianlong Song, Tianlong Liu, Xiaodong Yuan, Wenwu Luo, Changchun Chen, Dezhi Liu, Yuanyuan Zhu, Jie Liu, Wei Hu   +11 more
doaj   +1 more source

CAN3: BASELINE COST OF ILLNESS OF PARKINSON'S DISEASE IN A LARGE HEALTHCARE PLAN [PDF]

, 2000
We present a mixed finite element formulation for the spatial discretization in dynamic analysis of non-isothermal variably saturated porous media using different order of approximating functions for solid displacements and fluid pressures/temperature ...
Cao, Toan Duc, Sanavia, Lorenzo, Schrefler, B. A., Wang, Yongqi   +3 more
core   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan, Lynn Miller, Sam Wade, Jenni Ilomäki, Dickson Lukose, Jia Rong, Geoffrey I. Webb   +6 more
wiley   +1 more source

Adverse outcomes after primary PCI [PDF]

, 2011
Objective SYNTAX score II (SSII) is a long-term mortality prediction model to guide the decision making of the heart-team between coronary artery bypass grafting or percutaneous coronary intervention (PCI) in patients with left main or three-vessel ...
Hermanides, R.S. (Renicus)
core   +9 more sources

Efeito protetor de antagonista das gliproteínas IIb/IIa nas alterações hepáticas e pulmonares secundárias à isquemia e reperfusão do fígado em ratos Protective effects of an inhibitor of glycoprotein IIb/IIIa in the hepatic and pulmonary disturbances secondary to ischemia and reperfusion injury of rat’s liver

Arquivos de Gastroenterologia, 2007
RACIONAL: A lesão de isquemia e reperfusão hepática é um evento comum e responsável por considerável morbidade e mortalidade. OBJETIVO: Avaliar efeitos de inibidor da glicoproteína IIb/IIIa, cloridrato de tirofiban, nas alterações hepáticas e pulmonares ...
Leonardo F. Canedo, Marcel Autran C. Machado, Ana M. M. Coelho, Sandra N. Sampietre, Telesforo Bachella, Marcel C. C. Machado   +5 more
doaj   +1 more source

Case report: reuse of tirofiban leads to very severe thrombocytopenia

Frontiers in Cardiovascular Medicine, 2023
BackgroundTelofiban is a class of small molecule non-peptide tyrosine derivatives containing RGD sequences. It is the only platelet surface glycoprotein (GP) IIb/IIIa receptor antagonist (GPI) currently marketed in China.
Yuqing Li, Jiuchun Qiu, Yi Gao, Guangping Li   +3 more
doaj   +1 more source