A Systematic Invasive Strategy in non-ST Elevation Acute Coronary Syndromes: Is Age a Limiting Factor? [PDF]
Introdução: A estratégia terapêutica sistematicamente invasiva das síndromes coronárias agudas (SCA) é actualmente aceite como segura e eficaz, sendo crescentes as evidências da sua superioridade em relação a uma atitude conservadora.
Cruz Ferreira, R +7 more
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Elucidating the role of Staphylococcus epidermidis serine-aspartate repeat protein G in platelet activation. [PDF]
BACKGROUND: Staphylococcus epidermidis is a commensal of the human skin that has been implicated in infective endocarditis and infections involving implanted medical devices. S. epidermidis induces platelet aggregation by an unknown mechanism.
Arasu, S +6 more
core +2 more sources
ABSTRACT Background Up to 50% of patients with ST‐segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI) develop coronary microvascular dysfunction (CMD). Aims This study aims to assess whether a prothrombotic state of coronary blood, defined by thromboelastography (TEG), is associated with post ...
Roberto Scarsini +15 more
wiley +1 more source
Background: Despite successful opening of culprit coronary artery, myocardial reperfusion does not always follows primary percutaneous coronary intervention (PPCI).
Igor Matos Lago +9 more
doaj +1 more source
Bypass surgery versus stenting for the treatment of multivessel disease in patients with unstable angina compared with stable angina [PDF]
BACKGROUND: Earlier reports have shown that the outcome of balloon angioplasty or bypass surgery in unstable angina is less favorable than in stable angina.
Beyar, R. +14 more
core +3 more sources
Evaluation of CYP2C19 Clinical Decision Support Alerts to Guide P2Y12 Inhibitor Prescribing
P2Y12 inhibitor selection involves numerous factors, including CYP2C19 genetics, since evidence demonstrates reduced clopidogrel efficacy in patients with decreased or no function CYP2C19 variants. In 2020, Indiana University health embedded interruptive clinical decision support (CDS) alerts in the electronic health record (EHR) to recommend ...
Ashley N. Springer +14 more
wiley +1 more source
Platelet Inhibition in Percutaneous Coronary Interventions [PDF]
: Mechanical disruption of atherosclerotic plaques at the time of percutaneous coronary intervention (PCI) is a potent stimulus for arterial thrombosis.
Roffi, Marco, Wyss, Christophe
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Periprocedural antithrombotic management for lumbar puncture: Association of British Neurologists clinical guideline [PDF]
Lumbar puncture (LP) is an important and frequently performed invasive procedure for the diagnosis and management of neurological conditions. There is little in the neurological literature on the topic of periprocedural management of antithrombotics in ...
Chhetri, Suresh +3 more
core +1 more source
Early spontaneous systolic blood pressure (SBP) reduction after thrombectomy—without pharmacologic intervention—was independently associated with favorable outcomes in patients with anterior circulation large vessel occlusion stroke. Combining ΔSBP with nadir SBP within 30 min post‐procedure significantly improved predictive accuracy for 90‐day ...
Jianwen Bu, Guosen Bu, Yang Zhang
wiley +1 more source
Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction [PDF]
Recent clinical data show that the risk of coronary thrombosis after antiplatelet drugs withdrawal is much higher than that of surgical bleeding if they are continued.
Chassot, P.-G +2 more
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