Results 251 to 260 of about 70,024 (278)
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Metabolic regulation of tissue-resident memory CD8+ T cells
Current Opinion in Pharmacology, 2021Intracellular metabolic adaptations help define the function and homeostasis of memory CD8+ T cells. These cells, which promote protection against infections or cancer, undergo consecutive metabolic shifts, ultimately relying on mitochondrial-related pathways.
Trupti, Vardam-Kaur +2 more
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Tissue resident memory T cells in respiratory infections
Current Opinion in Infectious DiseasesPurpose of review We review the latest evidence that respiratory tissue resident memory T (T RM ) cells are key to local and immediate adaptive immunity to bacterial and viral infections of the respiratory tract and the implication for the design
Karen N, McCarthy, Kingston H G, Mills
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Axes of heterogeneity in human tissue‐resident memory T cells
Immunological Reviews, 2023SummaryTissue‐resident memory T cells (TRM) represent a dedicated layer of localized immune memory in virtually every organ throughout the human body. By virtue of their long‐term residence in disparate tissues, TRM are shaped by a myriad of site‐specific influences and exhibit remarkable heterogeneity in form and function.
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Emerging Concepts of Tissue-resident Memory T Cells in Transplantation
Transplantation, 2022In this review, we summarize and discuss recent advances in understanding the characteristics of tissue-resident memory T cells (TRMs) in the context of solid organ transplantation (SOT). We first introduce the traditionally understood noncirculating features of TRMs and the key phenotypic markers that define this population, then provide a detailed ...
Jianing, Fu, Megan, Sykes
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Memory T Cell Subsets, Migration Patterns, and Tissue Residence
Annual Review of Immunology, 2013Tissues such as the skin and mucosae are frequently exposed to microbial pathogens. Infectious agents must be quickly and efficiently controlled by our immune system, but the low frequency of naive T cells specific for any one pathogen means dependence on primary responses initiated in draining lymph nodes, often allowing time for ...
Scott N, Mueller +3 more
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Immunology
Psoriasis is a skin disease that is inflammatory and persistent, causing a high rate of recurrence, poor quality of life, and significant socioeconomic burden.
Guo-Shu Deng +10 more
semanticscholar +1 more source
Psoriasis is a skin disease that is inflammatory and persistent, causing a high rate of recurrence, poor quality of life, and significant socioeconomic burden.
Guo-Shu Deng +10 more
semanticscholar +1 more source
The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin
Nature Immunology, 2013Laura K. Mackay +14 more
semanticscholar +1 more source
Tissue-resident memory T cells: local specialists in immune defence
Nature reviews. Immunology, 2015Scott N. Mueller, Laura K. Mackay
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Arthritis & Rheumatology
To explore T cell‐intrinsic mechanisms underpinning the mal‐differentiation of tissue‐resident memory T (Trm) cells in patients with rheumatoid arthritis (RA).
Tong Wu +10 more
semanticscholar +1 more source
To explore T cell‐intrinsic mechanisms underpinning the mal‐differentiation of tissue‐resident memory T (Trm) cells in patients with rheumatoid arthritis (RA).
Tong Wu +10 more
semanticscholar +1 more source