Results 101 to 110 of about 97,379 (308)

NETworking for Health and in Disease: Neutrophil Extracellular Traps in Pediatric Surgical Care

Children
This comprehensive review examines the role of Neutrophil Extracellular Traps (NETs) in pediatric surgery. Focusing on NET formation, functions, and implications, this study highlights their dual impact in infection control and contribution to tissue ...
Maximilian Dölling, Martin Herrmann, Michael Boettcher   +2 more
doaj   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Podosome-type adhesions and focal adhesions, so alike yet so different.

, 2008
International audienceCell-matrix adhesions are essential for cell migration, tissue organization and differentiation, therefore playing central roles in embryonic development, remodeling and homeostasis of tissues and organs.
Millon-Fremillon, Angelique, Block, Marc, R., Cedric Badowski, Anne-Pascale Bouin, Faurobert, Eva, Emmanuelle Planus, Albiges-Rizo, Corinne, Badowski, Cedric, Eva Faurobert, Delphine Gerber-Scokaert, Corinne Albiges-Rizo, Marc R. Block, Daniel Bouvard, Bouin, Anne-Pascale, Planus, Emmanuelle, Bouvard, Daniel, Angelique Millon-Fremillon, Gerber-Scokaert, Delphine   +17 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Vascular complications during appendectomy: severe adhesion of the appendix to the right iliac artery: a case report

Journal of Medical Case Reports
Introduction Appendicitis is a common cause of acute abdomen. Rarely, it may form adhesions to nearby structures, complicating surgeries, especially when involving vascular structures such as the internal iliac artery, potentially causing severe ...
Ahmad Hosseinzadeh, Hoora Rezaeibana, Mohammadreza Khosravi, Armin Sourani, Hadis Yazdanshenas, Reza Shahriarirad   +5 more
doaj   +1 more source

A 3D printable tissue adhesive

Nature Communications
AbstractTissue adhesives are promising alternatives to sutures and staples for joining tissues, sealing defects, and immobilizing devices. However, existing adhesives mostly take the forms of glues or hydrogels, which offer limited versatility. We report a direct-ink-write 3D printable tissue adhesive which can be used to fabricate bioadhesive patches ...
Sarah J. Wu, Jingjing Wu, Samuel J. Kaser, Heejung Roh, Ruth D. Shiferaw, Hyunwoo Yuk, Xuanhe Zhao   +6 more
openaire   +3 more sources

Tissue adhesive in bronchial closure

The Annals of Thoracic Surgery, 1989
Monomeric n-butyl-2-cyanoacrylate was used in 25 patients undergoing pulmonary resections to strengthen the bronchial stump after pneumonectomy (n = 11) and to aid bronchial (n = 13) and tracheal anastomosis (n = 1) after sleeve resections. Neither group had any incidence of bronchopleural fistula. Bronchial anastomosis was accomplished in patients who
J, Eng, S, Sabanathan
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

The exertion of cell-cell adhesions

, 2016
Regulation of cadherin adhesion in tissue organization and malignant transformation.Cadherins are cell-cell adhesion molecules present in all tissues. Cadherins are transmembrane-proteins that form a homotypic, calcium-dependent complex with cadherins ...
Duc, Q. le, The exertion of cell-cell adhesions   +1 more
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