Results 51 to 60 of about 179,247 (290)

The characteristic time of glucose diffusion measured for muscle tissue at optical clearing [PDF]

, 2013
The study of agent diffusion in biological tissues is very important to understand and characterize the optical clearing effects and mechanisms involved: tissue dehydration and refractive index matching.
Carvalho, M I, Nogueira, E M, Oliveira, L M, Tuchin, Valery V.   +3 more
core   +2 more sources

FACT Or PACT: A Comparison Between Free-Acrylamide And Acrylamide-Based Passive Sodium Dodecyl Sulfate Tissue Clearing For Whole Tissue Imaging

Cell Journal, 2019
Major biological processes rely on the spatial organization of cells in complex, highly orchestrated three-dimensional (3D) tissues. Until the recent decade, most of information on spatial neural representation primarily came from microscopic imaging of “
Huimei Wang, Arezoo Khoradmehr, Amin Tamadon   +2 more
doaj   +1 more source

A method for ultrafast tissue clearing that preserves fluorescence for multimodal and longitudinal brain imaging

BMC Biology, 2022
Background Tissue-clearing techniques have recently been developed to make tissues transparent for three-dimensional (3D) imaging at different scales, including single-cell resolution. However, current tissue-clearing workflows have several disadvantages,
Qing-Hong Shan, Xin-Ya Qin, Nan Zhou, Chuan Huang, Yu Wang, Peng Chen, Jiang-Ning Zhou   +6 more
doaj   +1 more source

Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping [PDF]

, 2015
To facilitate fine-scale phenotyping of whole specimens, we describe here a set of tissue fixation-embedding, detergent-clearing and staining protocols that can be used to transform excised organs and whole organisms into optically transparent samples ...
A Bria, A Colomba, A Desmyter, A Ertürk, A Ertürk, A Ertürk, A Gautier, A Greenbaum, A Keppler, A Louveau, A Pifferi, A Rahman, A Seehaus, A Wilson, AA Grace, AJ Peters, AJ Schain, AL Alexander, Alon Greenbaum, AM Henry, Antti Lignell, Arthur D Edelstein, B Gutman, B Hammouda, B Hou, B Janssen, B Schmid, B Yang, B Zingg, Benjamin E Deverman, BH Mccormick, Bin Yang, BJ Connell, BJ Kim, BJ Vakoc, C Magnon, C Perruchini, CA Schneider, Charless C Fowlkes, Cheng Xiao, CN Bedbrook, CT Jones, D Bucher, D Pantazis, DE Otzen, DM Ramsey, DR Myatt, DS Richardson, E Baumgart, E Betzig, E Betzig, E Callaway, E Dominguez, E Lubeck, E Lubeck, E Meijering, E Pardon, EA Susaki, EHK Stelzer, EM Gibson, ER Barry, ES Lander, EY Hsiao, EY Hsiao, EY Hsiao, EY Hsiao, F Benmansour, F Chen, F De Chaumont, F Kaya, F Tournoux, FR Sharp, G Bartzokis, GA Ascoli, GJ Lieschke, GV Los, H Duong, H Hama, H Hintiryan, H Nakatomi, H Peng, H Peng, H Peng, H Peng, H Zhang, H-R Berthoud, H-U Dodt, HC Ott, HM Choi, HMT Choi, HS Sakhalkar, HU Dodt, IG Goldberg, J Akerboom, J Huisken, J Kohl, J Lehrer, J Livet, J Luisi, J Schindelin, J-C Rah, JA Miller, JC Tapia, JD Ross, Jennifer B Treweek, JK Fiege, JP Guyette, JR Glaser, JW Bohland, JW Lichtman, K Alitalo, K Becker, K Birmingham, K Chung, K Chung, K Fukamachi, K Kvilekval, K Smith, K Tainaka, KD Foust, KD Micheva, KD Piatkevich, Ken Y Chan, L Kuan, Long Cai, LW Miller, M Bajénoff, M Emmenlauer, M Hanoun, M Kollarik, M Kuwajima, M Kuwajima, M Linkert, M-T Ke, MA Goodell, MA Model, Mark S Ladinsky, MD Delp, MD Zhang, MG Gustafsson, MH Longair, MJ Rust, MS George, MT Ke, N Kasthuri, N Kasthuri, N Renier, Nicholas C Flytzanis, P Bianco, P Chothani, P Gleeson, P Gleeson, P Kankaanpaa, P Taupin, Pamela J Bjorkman, PC Fridy, PJ Basser, PJ Keller, PK Singh, PS Huppi, Q Sattentau, R Parekh, R Scorcioni, R Tomer, RC Craddock, RK Ernst, RM White, S Masich, S Mendez-Ferrer, S Preibisch, S Reardon, S Tsuriel, SJ Morrison, SM Lucas, SP Bach, SW Hell, SW Oh, SY Kim, SY Tan, T Kaletta, T Kuwajima, T Li, T Pietzsch, T Ragan, T Reineke, T Staudt, T Sugiyama, TO Videen, TW Chen, U Kragh-Hansen, U Sumbul, Viviana Gradinaru, VJ Dercksen, X Ming, Y Aoyagi, Y Omatsu, Y Zoukos, Z Wu   +197 more
core   +2 more sources

Global Connectivity and Function of Descending Spinal Input Revealed by 3D Microscopy and Retrograde Transduction [PDF]

, 2018
The brain communicates with the spinal cord through numerous axon tracts that arise from discrete nuclei, transmit distinct functions, and often collateralize to facilitate the coordination of descending commands.
Blackmore, Murray G., Maunze, Brian, Tsoulfas, Pantelis, Wang, Yunfang, Wang, Zimei   +4 more
core   +2 more sources

Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND) [PDF]

, 2018
A key challenge in medical imaging is determining a precise correspondence between image properties and tissue microstructure. This comparison is hindered by disparate scales and resolutions between medical imaging and histology.
Ball, G, Edwards, A D, Jones, M, So, P-W, Stolp, H B, Thornton, C, Tournier, J-D   +6 more
core   +6 more sources

Optimized Protocol for Imaging Cleared Neural Tissues Using Light Microscopy [PDF]

, 2016
Understanding physical and chemical processes at an organismal scale is a fundamental goal in biology. While science is adept at explaining biological phenomena at both molecular and cellular levels, understanding how these processes translate to ...
Bergan, J, Dulac, C, Isogai, Y, Richardson, DS   +3 more
core   +1 more source

Chemical clearing and dehydration of GFP expressing mouse brains.

PLoS ONE, 2012
Generally, chemical tissue clearing is performed by a solution consisting of two parts benzyl benzoate and one part benzyl alcohol. However, prolonged exposure to this mixture markedly reduces the fluorescence of GFP expressing specimens, so that one has
Klaus Becker, Nina Jährling, Saiedeh Saghafi, Reto Weiler, Hans-Ulrich Dodt   +4 more
doaj   +1 more source

Effects of endocrine-disrupting chemical exposure on zebrafish ovarian follicles [PDF]

, 2017
The process of oocyte maturation involves both nuclear and cytoplasmic events that are essential for the production of viable eggs and subsequent fertilization in sexually reproducing animals.
D\u27Angelo, Josephine, Freeman, Edward A.   +1 more
core   +2 more sources

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source