Results 31 to 40 of about 179,247 (290)
Quantification of light attenuation in optically cleared mouse brains [PDF]
Optical clearing, in combination with recently developed optical imaging techniques, enables visualization and acquisition of high-resolution, three-dimensional images of biological structures deep within the tissue. Many different approaches can be used
d'Esposito, A +4 more
core +1 more source
Tissue clearing has become an important tool for the investigation of biological systems in three dimensions. However, many pioneering techniques were based on serendipitous discoveries. Next-generation clearing methods have been (re)designed with a better understanding of the chemistry and physics required to equalize the refractive index throughout a
Douglas S, Richardson, Jeff W, Lichtman
openaire +2 more sources
LiverClear: A versatile protocol for mouse liver tissue clearing
Summary: Although there are numerous tissue clearing protocols, most are inadequate for clearing liver tissue. Here we present a flexible protocol for mouse liver tissue; we combine strategies from several previously published protocols for delipidation,
Laura M. Molina +8 more
doaj +1 more source
Diffusion characteristics of ethylene glycol in skeletal muscle [PDF]
Part of the optical clearing study in biological tissues concerns the determination of the diffusion characteristics of water and optical clearing agents in the subject tissue.
Carvalho, Maria Inês +3 more
core +1 more source
Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease [PDF]
Three-dimensional tissue-structural relationships are not well captured by typical thin-section histology, posing challenges for the study of tissue physiology and pathology. Moreover, while recent progress has been made with intact methods for clearing,
Arda, H. Efsun +14 more
core +2 more sources
Optical clearing-aided photoacoustic microscopy with enhanced resolution and imaging depth [PDF]
Due to strong light scattering in tissue, both the spatial resolution and maximum penetration depth of optical-resolution photoacoustic microscopy (OR-PAM) deteriorate sharply with depth.
Wang, Lihong V., Yao, Junjie, Zhou, Yong
core +2 more sources
Tissue optical clearing mechanisms
The high scattering and absorption of opaque tissues limit the penetration of light into deep tissues, limiting the imaging depth of various optical imaging techniques. The proposed tissue optical clearing technique provides an innovative way to perform deep-tissue imaging. Recently, various optical clearing methods have been developed.
Yu, T. +5 more
openaire +2 more sources
Soft tissue tumors: Clear cell sarcoma [PDF]
Review on Soft tissue tumors: Clear cell sarcoma, with data on clinics, and the genes involved.
Poppe, Bruce +3 more
openaire +2 more sources
Comprehensive Evaluation of Peripheral Nerve Regeneration in the Acute Healing Phase Using Tissue Clearing and Optical Microscopy in a Rodent Model [PDF]
Peripheral nerve injury (PNI), a common injury in both the civilian and military arenas, is usually associated with high healthcare costs and with patients enduring slow recovery times, diminished quality of life, and potential long-term disability ...
Evans, Conor L. +7 more
core +3 more sources
Three-dimensional microscopic analysis of clinical prostate specimens [PDF]
__Aims:__ Microscopic evaluation of prostate specimens for both clinical and research purposes is generally performed on 5-μm-thick tissue sections.
Cappellen, W.A. (Gert) van +6 more
core +1 more source

