Results 71 to 80 of about 968,773 (372)

MicroBundleCompute: Automated segmentation, tracking, and analysis of subdomain deformation in cardiac microbundles [PDF]

arXiv, 2023
Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to regenerative tissue engineering. Yet, alongside these potential opportunities comes a critical challenge: attaining mature hiPSC-CM tissues.
arxiv  

Tissue culture of oil palm : finding the balance between mass propagation and somaclonal variation [PDF]

, 2019
The oil palm (Elaeis guineensis Jacq.) is typically propagated in vitro by indirect somatic embryogenesis, a process in which somatic cells of an explant of choice are, via an intermediate phase of callus growth, induced to differentiate into somatic ...
Inzé, Dirk, Maene, Ludo, Weckx, Sylvie
core   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Simultaneous self-organization of arterial and venous networks driven by the physics of global power optimization [PDF]

arXiv, 2023
Understanding of vascular organization is a long-standing problem in quantitative biology and biophysics and is essential for the growth of large cultured tissues. Approaches are needed that (1) make predictions of optimal arteriovenous networks in order to understand the natural vasculatures that originate from evolution (2) can design vasculature for
arxiv  

Neuronal micro-culture engineering by microchannel devices of cellular scale dimensions [PDF]

Biomedical Engineering Letters, May 2011, Volume 1, Issue 2, pp 89-98, 2015
Purpose: The purpose of the current study was to investigate the effect of microchannel geometry on neuronal cultures and to maintain these cultures for long period of time (over several weeks) inside the closed microchannels of cellular scale dimensions.
arxiv   +1 more source

Research Notes: Soybean tissue culture [PDF]

, 1981
The recently developed techniques of plant tissue culture have been used to develop somatic cell geneti cs programs in solanaceous species , particularly Petunia , Nicotiana, and Datura (Vasil et al., 1979).
Evans, David A.
core   +2 more sources

New methods for chicken embryo manipulations [PDF]

, 2010
The capacity to image a growing embryo while simultaneously studying the developmental function of specific molecules provides invaluable information on embryogenesis.
De Bellard, Maria Elena, El-Ghali, Nissrine, Ezin, Akouavi M., Rabadi, Maes   +3 more
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

A strategy to tailor the mechanical and degradation properties of PCL-PEG-PCL based copolymers for biomedical application [PDF]

European Polymer Journal 198, 112388, 2023, 2023
Biodegradable and biocompatible 3D printable biomaterials with tunable mechanical properties and degradation rate adapted to target tissues were urgently required to manufacture scaffolds for tissue regeneration. Herein, a strategy based on a series of copolymers are proposed where the mechanical and degradation properties can be optimized regarding ...
arxiv