Results 41 to 50 of about 3,009,910 (332)

Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling [PDF]

, 2003
Background— Transplantation of endothelial progenitor cells (EPCs) improves vascularization and left ventricular function after experimental myocardial ischemia.
Aicher, A, Assmus, B, Badorff, C, Brenner, W, Dimmeler, S, Eckey, T, Henze, E, Massoudi, S, Zeiher, AM, Zuhayra, M   +9 more
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Pharmacokinetics, Tissue Distribution and Excretion of a Novel Diuretic (PU-48) in Rats

Pharmaceutics, 2018
Methyl 3-amino-6-methoxythieno [2,3-b] quinoline-2-carboxylate (PU-48) is a novel diuretic urea transporter inhibitor. The aim of this study is to investigate the profile of plasma pharmacokinetics, tissue distribution, and excretion by oral dosing of PU-
Zhi-Yuan Zhang, Hua Zhang, Dan Liu, Ying-Yuan Lu, Xin Wang, Pu Li, Ya-Qing Lou, Bao-Xue Yang, Ya-Xin Lou, Chuang Lu, Qiang Zhang, Guo-Liang Zhang   +11 more
doaj   +1 more source

THE DISTRIBUTION OF ESTERASES IN MOUSE TISSUES [PDF]

Journal of Histochemistry & Cytochemistry, 1959
The esterases contained in 32 mouse tissues and organs have been analyzed using the zymogram technique. More than ten different esterases have been resolved and partly characterized by their substrate and inhibition specificities. The esterases compose a family of distinct enzymes with overlapping specificities, and the total activity in any tissue is
Robert L. Hunter, Clement L. Markert
openaire   +3 more sources

Expression, Tissue Distribution and Function of miR-21 in Esophageal Squamous Cell Carcinoma [PDF]

, 2013
Objective:MiR-21 is an oncomir expressed by malignant cells and/or tumor microenvironment components. In this study we focused on understanding the effects of stromal miR-21 on esophageal malignant cells.Design:MiR-21 expression was evaluated in formalin-
Calin, G.A., Mowla, S.J., Naghshvar, F., Nouraee, N., Omidi, A.A., Samaei, N.M., Semnani, S., Van Roosbroeck, K., Vasei, M.   +8 more
core   +3 more sources

Oral delivery of lycopene-loaded microemulsion for brain-targeting: preparation, characterization, pharmacokinetic evaluation and tissue distribution

Drug Delivery, 2019
Lycopene is considered as a promising neuroprotector with multiple bioactivities, while its therapeutic use in neurological disorders is restricted due to low solubility, instability and limited bioavailability.
Yunliang Guo, Xuyan Mao, Jing Zhang, Peng Sun, Haiyang Wang, Yue Zhang, Yingjuan Ma, Song Xu, Renjun Lv, Xueping Liu   +9 more
doaj   +1 more source

Pharmacokinetics, Tissue Distribution and Excretion of Isoalantolactone and Alantolactone in Rats after Oral Administration of Radix Inulae Extract

Molecules, 2015
Radix Inulae is endemic to China and has been used in traditional medicine to treat upper body pain, emesis and diarrhoea, and to eliminate parasites. Here, an UPLC-MS/MS method was developed and applied to study the pharmacokinetics, distribution and ...
Renjie Xu, Guisheng Zhou, Ying Peng, Mengyue Wang, Xiaobo Li   +4 more
doaj   +1 more source

Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]

, 2020
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D., Bell, J.D., Thomas, E.L., Thomas, E.L., Whitcher, B., Whitcher, B., Yaghootkar, H., Yaghootkar, H.   +7 more
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Pre-Clinical Pharmacokinetics, Tissue Distribution and Physicochemical Studies of CLBQ14, a Novel Methionine Aminopeptidase Inhibitor for the Treatment of Infectious Diseases

Drug Design, Development and Therapy, 2020
Oscar Ekpenyong, Xiuqing Gao, Jing Ma, Candace Cooper, Linh Nguyen, Omonike A Olaleye, Dong Liang, Huan Xie Department of Pharmaceutical and Environmental Health Sciences, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX ...
Ekpenyong O, Gao X, Ma J, Cooper C, Nguyen L, Olaleye OA, Liang D, Xie H   +7 more
doaj  

Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

, 2015
Light propagating in tissue attains a spectrum that varies with location due to wavelength-dependent fluence attenuation by tissue optical properties, an effect that causes spectral corruption.
Bayer, Christine, Glasl, Sarah, Multhoff, Gabriele, Ntziachristos, Vasilis, Nunes, Antonio, Olefir, Ivan, Stangl, Stefan, Symvoulidis, Panagiotis, Tzoumas, Stratis   +8 more
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Study on Formulation, in vivo Exposure, and Passive Targeting of Intravenous Itraconazole Nanosuspensions

Frontiers in Pharmacology, 2019
The pharmacokinetic profile of a drug can be different when delivered as a nanosuspension compared with a true solution, which may in turn affect the therapeutic effect of the drug.
Qi Yuan, Yanling Wang, Rufeng Song, Xianqiao Hou, Keke Yu, Jiaojiao Zheng, Juanmei Zhang, Xiaohui Pu, Jihong Han, Lanlan Zong   +9 more
doaj   +1 more source