Results 41 to 50 of about 12,729,869 (376)

Perivascular adipose tissue as a relevant fat depot for cardiovascular risk in obesity [PDF]

, 2018
Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD), myocardial infarction, and congestive heart failure.
Costa, Rafael M., Lobato, Núbia S., Neves, Karla B., Tostes, Rita C.   +3 more
core   +3 more sources

Expression Patterns of PACAP and PAC1R Genes and Anorexigenic Action of PACAP1 and PACAP2 in Zebrafish

Frontiers in Endocrinology, 2019
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide with potent suppressive effects on feeding behavior in rodents, chicken, and goldfish. Teleost fish express two PACAPs (PACAP1, encoded by the adcyap1a gene, and PACAP2, encoded
Tomoya Nakamachi, Ayano Tanigawa, Norifumi Konno, Seiji Shioda, Kouhei Matsuda   +4 more
doaj   +1 more source

Change of metformin concentrations in the liver as a pharmacological target site of metformin after long-term combined treatment with ginseng berry extract

Frontiers in Pharmacology, 2023
Metformin as an oral glucose-lowering drug is used to treat type 2 diabetic mellitus. Considering the relatively high incidence of cardiovascular complications and other metabolic diseases in diabetic mellitus patients, a combination of metformin plus ...
Choong Whan Lee, Byoung Hoon You, Sreymom Yim, Seung Yon Han, Hee-Sung Chae, Hee-Sung Chae, Mingoo Bae, Seo-Yeon Kim, Jeong-Eun Yu, Jieun Jung, Piseth Nhoek, Hojun Kim, Han Seok Choi, Young-Won Chin, Hyun Woo Kim, Young Hee Choi   +15 more
doaj   +1 more source

Pure phase-encoded MRI and classification of solids [PDF]

, 1995
Here, the authors combine a pure phase-encoded magnetic resonance imaging (MRI) method with a new tissue-classification technique to make geometric models of a human tooth.
Barr, Alan H., Fleischer, Kurt W., Ghosh, Pratik, Jacobs, Russell E., Laidlaw, David H.   +4 more
core   +1 more source

Adipose Tissue Distribution and Cardiovascular Disease Risk Among Breast Cancer Survivors.

Journal of Clinical Oncology, 2019
PURPOSE Cardiovascular disease (CVD) is a major source of morbidity and mortality among breast cancer survivors. Although body mass index (BMI) is associated with CVD risk, adipose tissue distribution may better identify patients with a high risk of CVD ...
Elizabeth M. Cespedes Feliciano, Wendy Y Chen, P. Bradshaw, C. Prado, Stacey E. Alexeeff, K. Albers, A. Castillo, B. Caan   +7 more
semanticscholar   +1 more source

Preclinical Pharmacokinetics, Tissue Distribution, and Primary Safety Evaluation of Indo5, a Novel Selective Inhibitor of c-Met and Trks

Frontiers in Pharmacology, 2021
The compound [3-(1H-benzimidazol-2-methylene)-5-(2-methylphenylaminosulfo)-2-indolone], known as Indo5, is a novel selective inhibitor of c-Met and Trks, and it is a promising anticancer candidate against hepatocellular carcinoma (HCC).
Teng Luo, Teng Luo, Teng Luo, Fei-Xiang Zhang, Ke Zhao, Hui-Ying Gao, Shou-Guo Zhang, Lin Wang, Gui-Fang Dou, Ting Liu, Miao Yu, Yi-Qun Zhan, Hui Chen, Xiao-Ming Yang, Xiao-Ming Yang, Chang-Yan Li, Chang-Yan Li   +16 more
doaj   +1 more source

Analysis of healthy sitting behavior: Interface pressure distribution and subcutaneous tissue oxygenation [PDF]

, 2009
Pressure ulcers are a large problem in individuals who use a wheelchair for their mobility and have limited trunk stability and motor function. Because no relation between interface pressure and pressure ulcer development has been established and no ...
Geffen, Paul van, IJzerman, Maarten, Jannink, Michiel, Nederhand, Marc, Reenalda, Jasper, Rietman, Hans   +5 more
core   +2 more sources

Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]

, 2020
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D., Bell, J.D., Thomas, E.L., Thomas, E.L., Whitcher, B., Whitcher, B., Yaghootkar, H., Yaghootkar, H.   +7 more
core   +2 more sources

Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling [PDF]

, 2003
Background— Transplantation of endothelial progenitor cells (EPCs) improves vascularization and left ventricular function after experimental myocardial ischemia.
Aicher, A, Assmus, B, Badorff, C, Brenner, W, Dimmeler, S, Eckey, T, Henze, E, Massoudi, S, Zeiher, AM, Zuhayra, M   +9 more
core   +1 more source

Pharmacokinetic and Tissue Distribution of Fucoidan from Fucus vesiculosus after Oral Administration to Rats

Marine Drugs, 2018
Fucus vesiculosus L., known as bladderwrack, belongs to the brown seaweeds, which are widely distributed throughout northern Russia, Atlantic shores of Europe, the Baltic Sea, Greenland, the Azores, the Canary Islands, and shores of the Pacific Ocean ...
O. Pozharitskaya, A. Shikov, N. M. Faustova, E. Obluchinskaya, V. Kosman, H. Vuorela, V. Makarov   +6 more
semanticscholar   +1 more source