Results 81 to 90 of about 12,729,869 (376)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells

open access: yesViruses, 2022
Tissue and subcellular localization and its changes upon cell activation of virus-restricting APOBEC3 at protein levels are important to understanding physiological functions of this cytidine deaminase, but have not been thoroughly analyzed in vivo.
Shota Tsukimoto   +8 more
doaj   +1 more source

Expression of transforming growth factor-beta isoforms and their receptors in chronic tendinosis [PDF]

open access: yes, 2001
Chronic tendon lesions are degenerative conditions and may represent a failure to repair or remodel the extracellular matrix after repeated micro-injury.
Curry, V   +5 more
core   +2 more sources

Fluoride Tissue Distribution: Intracellular Fluoride Concentrations

open access: yesExperimental Biology and Medicine, 1980
AbstractThe distribution of fluoride and chloride in muscle, liver, and tendon was studied in groups of 6-15 rats sacrificed at 80-240 min after intraperitoneal injections containing radiofluoride (18F) and radiochloride (36Cl). Liver exhibited a constant 18F(tissue water):18F(plasma water) ratio over 120-220 min and this ratio was constant in muscle ...
W D, Armstrong, L, Singer
openaire   +2 more sources

The Metabolic Phenotype in Obesity: Fat Mass, Body Fat Distribution, and Adipose Tissue Function

open access: yesObesity Facts, 2017
The current obesity epidemic poses a major public health issue since obesity predisposes towards several chronic diseases. BMI and total adiposity are positively correlated with cardiometabolic disease risk at the population level.
G. Goossens
semanticscholar   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Tissue Distribution of Lipoprotein Lipase (LPL) and Regulation of LPL Gene Expression Induced by Insulin and Glucose in Goose Primary Hepatocytes

open access: yesThe Journal of Poultry Science, 2010
The study was to research the gene expression of lipoprotein lipase (LPL) in abdomen adipose tissue, subcutaneous adipose tissue, pectoral muscle, skeletal muscles, liver, brain and spleen of geese, and the effect of insulin and glucose on gene ...
Chunchun Han   +5 more
doaj   +1 more source

Pharmacokinetics, Tissue Distribution and Excretion of Demethyleneberberine, a Metabolite of Berberine, in Rats and Mice

open access: yesMolecules, 2023
Demethyleneberberine is an active component extracted from the Chinese herbal drug Cortex Phellodendri. It is also a metabolite of berberine in animals and humans.
Jingqi Li   +4 more
doaj   +1 more source

Postmortem tissue distribution of morphine and its metabolites in a series of heroin related deaths [PDF]

open access: yes, 2018
The abuse of heroin (diamorphine) and heroin deaths are growing around the world. The interpretation of the toxicological results from suspected heroin deaths is notoriously difficult especially in cases where there may be limited samples.
Beer, Lewis J.   +6 more
core   +5 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

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