Results 81 to 90 of about 8,064,162 (313)

The Effects of Cynara scolymus L. Leaf and Cichorium intybus L. Root Extracts on Carbon Tetrachloride Induced Liver Toxicity in Rats

open access: yesJournal of Medicinal Plants, 2011
Background: Cynara scolymus and Cichorium intybus are popular herbal remedy in folk medicine for liver disorders. Although many experimental studies carried out, scientifically reliable data needed to verify minimum effective dosage and efficacy of these
H Fallah Huseini   +6 more
doaj  

Choline esters in tissue extracts [PDF]

open access: yesThe Journal of Physiology, 1933
H C, Chang, J H, Gaddum
openaire   +2 more sources

Identification and Characterization of Immunodominant Proteins from Tick Tissue Extracts Inducing a Protective Immune Response against Ixodes ricinus in Cattle. [PDF]

open access: yesVaccines (Basel), 2021
Knorr S   +10 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Antifungal Activity in Extracts of Plants from Southwestern Oklahoma Against Aspergillus Flavus

open access: yesOklahoma Native Plant Record, 2015
The use of medicinal plants has been an integral part of human civilization since antiquity. Naturally occurring pesticidal compounds are synthesized by the plant defense system, which includes antimicrobial proteins and lower molecular weight natural ...
Tahzeeba Frisby
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Auto-Antigenicity of Connective Tissue Extracts.

open access: yesExperimental Biology and Medicine, 1963
Summary1. Rabbit tendon extracts, reinjected into the donor animals produced circulating complement fixing antibodies, skin reactivity of the delayed type and fixation of antibody to synovia and interstitial spaces of several organs. 2. The growth of the animals was stunted, but no other abnormalities were demonstrable. 3.
P, HELLER, V J, YAKULIS
openaire   +2 more sources

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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