Results 121 to 130 of about 8,614,068 (306)
, 2003 SummaryTissue factor pathway inhibitor (TFPI) abrogates coagulation initiated by the factor VIIa/tissue factor catalytic complex. While the gene structure of TFPI suggests that it is a secreted protein, a large pool of TFPI is associated with the ...
Garnet Jack +5 more
core +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Hemostatic imbalance underlying preterm delivery in COVID-19 convalescent patients
Акушерство, гинекология и репродукцияAim: to study the role of the hemostatic system in pretem delivery in pregnant women who have had COVID-19 in the gestation period from 14 to 16 weeks.Materials and Methods.
M. G. Nikolaeva +3 more
doaj +1 more source
Endothelial cells, tissue factor and infectious diseases
, 2003 Tissue factor is a transmembrane procoagulant glycoprotein and a member of the cytokine receptor superfamily. It activates the extrinsic coagulation pathway, and induces the formation of a fibrin clot.
S.G. Filler, L.M. Lopes-Bezerra
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
This BCTB tissue subcollection consists of fresh tissue samples, that is, pieces of tissue placed in liquid nitrogen for freezing.
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, 2017 Aims Connective tissue growth factor (CTGF) is an emerging marker for tissue fibrosis. We investigated the association between CTGF and cardiac diastolic function using cellular and animal models and clinical human data Methods and results A total of ...
Wu, Cho-Kai;Wang, Yi-Chih;Lee, Jen-Kuang;Chang, Sheng-Nan;Su, Mao-Yuan;Yeh, Huei-Ming;Su, Ming-Jai;Chen, Jin-Jer;Chiang, Fu-Tien;Hwang, Juey-Jen;Lin, Jiunn-Lee;Tsai, Chia-Ti +1 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
BCTB Tissue Samples and Associated Images
This BCTB subcollection consists of tissue samples taken from breast cancer patients and others. It is further broken down into a number of types of tissue, some of which have associated microscope images.
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