Results 51 to 60 of about 1,251,677 (333)

Correlates of plasma and platelet tissue factor pathway inhibitor, factor V, and Protein S

Research and Practice in Thrombosis and Haemostasis, 2017
Essentials Tissue Factor Pathway Inhibitor, Protein S, and Factor V circulate in plasma and platelet pools. These proteins were measured in plasma and platelets from 435 healthy subjects and correlated.
P. Ellery, I. Hilden, K. Sejling, M. Loftager, Nicholas D Martinez, S. Maroney, A. Mast   +6 more
semanticscholar   +1 more source

Plasma Tissue Factor Pathway Inhibitor Levels in Angiographically Defined Coronary Artery Disease Among Saudis

Oman Medical Journal, 2013
Objectives: This study was aimed to determine plasma levels of total (TFPI-T) and free (TFPI-F) tissue factor pathway inhibitor, plasminogen activator inhibitor-1 (PAI-1), and tissue plasminogen activator (t-PA) in a cohort of Saudi patients with chronic
Syed Shahid Habib
doaj   +1 more source

Urinary pro-thrombotic, anti-thrombotic, and fibrinolytic molecules as biomarkers of lupus nephritis

Arthritis Research & Therapy, 2019
Objective This study evaluates the utility of urinary pro-thrombotic molecules such as tissue factor (TF), anti-thrombotic molecules such as tissue factor pathway inhibitor (TFPI), and fibrinolytic molecules such as plasmin and d-dimer as biomarkers of ...
Ling Qin, Samantha Stanley, Huihua Ding, Ting Zhang, Van Thi Thanh Truong, Teja Celhar, Anna-Marie Fairhurst, Claudia Pedroza, Michelle Petri, Ramesh Saxena, Chandra Mohan   +10 more
doaj   +1 more source

Diurnal variations in tissue factor and tissue factor pathway inhibitor concentrations in relation to on-treatment platelet reactivity: an analysis of patients with acute myocardial infarction

Platelets, 2020
The aim of the study was to evaluate diurnal changes of tissue factor (TF) and tissue factor pathway inhibitor (TFPI) concentrations in relation to on-treatment platelet reactivity.
Joanna Boinska, Marek Koziński, Michał Kasprzak, Katarzyna Ziołkowska, Inga Dziembowska, Michał Ziołkowski, Jacek Kubica, Danuta Rość   +7 more
doaj   +1 more source

Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets. [PDF]

, 2017
BackgroundLiposarcoma, the most common soft tissue tumor, is understudied cancer, and limited progress has been made in the treatment of metastatic disease.
Doan, Ngan B, Forscher, Charles, Garg, Manoj, Kanojia, Deepika, Koeffler, H Phillip, Luty, Samuel B, M T, Anand, Martinez, Jacqueline, Said, Jonathan W, Tyner, Jeffrey W   +9 more
core   +2 more sources

GBM radiosensitizers: dead in the water…or just the beginning? [PDF]

, 2017
The finding that most GBMs recur either near or within the primary site after radiotherapy has fueled great interest in the development of radiosensitizers to enhance local control.
Bindra, Ranjit S., Chalmers, Anthony J., Dewhirst, Mark, Evans, Sydney   +3 more
core   +1 more source

Low levels of tissue factor pathway inhibitor increase the risk of cerebral venous thrombosis

Advanced Biomedical Research, 2015
Background: Decreased concentration of tissue factor pathway inhibitor (TFPI) is a risk factor for development of deep venous thrombosis and coronary heart disease, but there is no evidence for the relationship between TFPI and cerebral venous and sinus ...
Shaghayegh Haghjooy Javanmard, Tayebeh Shahsavarzadeh, Mohammad Saadatnia   +2 more
doaj   +1 more source

Bivalirudin in combination with heparin to control mesenchymal cell procoagulant activity. [PDF]

PLoS ONE, 2012
Islet and hepatocyte transplantation are associated with tissue factor-dependent activation of coagulation which elicits instant blood mediated inflammatory reaction, thereby contributing to a low rate of engraftment.
Xavier Stephenne, Emanuele Nicastro, Stephane Eeckhoudt, Cedric Hermans, Omar Nyabi, Catherine Lombard, Mustapha Najimi, Etienne Sokal   +7 more
doaj   +1 more source

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes [PDF]

, 2010
Histone deacetylases (HDACs) regulate the acetylation of histones in the control of gene expression. Many non-histone proteins are also targeted for acetylation, including TGF-ß signalling pathway components such as Smad2, Smad3 and Smad7. Our studies in
Andrew D. Rowan, Bain, Cao, Chen, Chen, Cho, Clayton, David A. Young, de Ruijter, Denker, Dennler, Derynck, Dylan R. Edwards, Fecteau, Gary J. Litherland, Ghosh, Glenisson, Glozak, Gottlicher, Gregoretti, Gurvich, Hazzalin, Horowitz, Ian M. Clark, Khan, Kobayashi, Kouzarides, Kuang, Kwak, Le Pabic, Le Pabic, Lee, Leon Pybus, Li, Lien, Litherland, Mahlknecht, Matt J. Barter, Michaelis, Rombouts, Shi, Tim E. Cawston, Togi, Tu, Vannini, Verdin, Wang, Whitmarsh, Wrana, Xu, Yamaguchi, Yoshikawa, Young, Yu, Zhang   +54 more
core   +1 more source

Heparanase enhances the generation of activated factor X in the presence of tissue factor and activated factor VII

Haematologica, 2010
Background Heparanase is an endo-β-D-glucuronidase dominantly involved in tumor metastasis and angiogenesis. Recently, we demonstrated that heparanase is involved in the regulation of the hemostatic system.
Yona Nadir, Benjamin Brenner, Liat Fux, Itay Shafat, Judith Attias, Israel Vlodavsky   +5 more
doaj   +1 more source