Results 101 to 110 of about 372,734 (326)

Alternative tissue fixation for combined histopathological and molecular analysis in a clinically representative setting. [PDF]

Histochem Cell Biol, 2021
Meecham A, Miranda E, Morris HT, Hair J, Oien KA, Gerrard G, Guppy N, Mooney D, Shaw EC, Ashton-Key M, Lees R, Flanagan A, Rodriguez-Justo M.   +12 more
europepmc   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Making a science out of preanalytics: An analytical method to determine optimal tissue fixation in real-time. [PDF]

PLoS One, 2021
Bauer DR, Leibold T, Chafin DR.
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Tissue fixation effects on human retinal lipid analysis by MALDI imaging and LC-MS/MS technologies. [PDF]

J Mass Spectrom, 2021
Kotnala A, Anderson DMG, Patterson NH, Cantrell LS, Messinger JD, Curcio CA, Schey KL.   +6 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Vital Perfusion-Fixation Technique Through Carotid Arteries for Preparation of Histologic Sections from Periodontium and Jaw Bone of Dog

مجله دانشکده دندانپزشکی اصفهان, 2005
processing of tissues before histologic slices is necessary for preparation of proper histologic sections in animal studies. Fixation is one of the most important and early laboratory stages of tissue processing.
AA - Basiri, M Atabaki, Sh Adibi
doaj  

Quantitative assessment of fixation strength in combined thread lifting: Comparative analysis of bidirectional-multidirectional versus double bidirectional thread combinations

JPRAS Open
Background: The efficacy of thread lifting procedures for facial rejuvenation is significantly influenced by thread fixation strength and tissue stabilization capabilities. This study presents a quantitative biomechanical comparison between bidirectional
Kyu-Ho Yi, Soo Yeon Park, Jovian Wan, Jong Keun Song, Jin-Hyun Kim, Erik Koppert, Jae Young Kim   +6 more
doaj   +1 more source

In Vivo Kinematic Analysis of Lateral Meniscal Allograft Transplantation With Soft Tissue Fixation. [PDF]

Orthop J Sports Med, 2021
Macchiarola L, Di Paolo S, Grassi A, Dal Fabbro G, Lucidi GA, Cucurnia I, Zaffagnini S.   +6 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source