Results 101 to 110 of about 4,427,559 (374)
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
A Simple Technique for Reconstruction of the Medial Patellofemoral Ligament With Patellar Soft-Tissue Fixation Using Synthetic Suture Tape Internal Bracing. [PDF]
Arthrosc Tech, 2023 Berger P, Vandenneucker H, Bellemans J.
europepmc +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Revisiting PFA-mediated tissue fixation chemistry: FixEL enables trapping of small molecules in the brain to visualize their distribution changes. [PDF]
Chem, 2023 Nonaka H +14 more
europepmc +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Maps of Visual Importance [PDF]
arXiv, 2017 The importance of an element in a visual stimulus is commonly associated with the fixations during a free-viewing task. We argue that fixations are not always correlated with attention or awareness of visual objects. We suggest to filter the fixations recorded during exploration of the image based on the fixations recorded during recalling the image ...
arxiv
Survivorship and Reoperation of 324 Consecutive Isolated or Combined Arthroscopic Meniscal Allograft Transplants Using Soft Tissue Fixation. [PDF]
Am J Sports Med, 2023 Grassi A +7 more
europepmc +1 more source
FEBS Open Bio, EarlyView.We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei +6 more
wiley +1 more source
Fixation probability and fixation time in structured populations [PDF]
arXiv, 2018 The rate of biological evolution depends on the fixation probability and on the fixation time of new mutants. Intensive research has focused on identifying population structures that augment the fixation probability of advantageous mutants. But these `amplifiers of natural selection' typically increase fixation time. Here we study population structures
arxiv