Results 51 to 60 of about 4,427,559 (374)

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Towards safer non-volatile tissue fixatives: Evaluation of choline-based ionic liquids for fixing ocular tissues

Ecotoxicology and Environmental Safety, 2021
Volatile organic chemicals (VOCs) are routinely used for processing biological tissue samples in clinical laboratories. Recognizing their serious health and environmental impacts, a few non-volatile green solvents (choline based ionic liquids, ILs) were ...
P.R. Deepa, V. Nalini, M. Surianarayanan, S. Krishnakumar   +3 more
doaj  

Effects of Varying the Vehicle for OsO4 in Tissue Fixation

The Journal of Biophysical and Biochemical Cytology, 1957
I t is well known that the quality of OsO4 fixation of tissue cells obtained with any one of the several recommended mixtures (1-3) may vary considerably in the same block or from one tissue to another.
J. Caulfield
semanticscholar   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

FEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan, Rosa Sanchez‐Alvarez, Chiho Kambara, Poojitha Rajasekar, Yuluang Wang, François Halloy, Jonathan Hall, Hans‐Jürgen Stark, Iris Martin, Petra Boukamp, Svitlana Kurinna   +10 more
wiley   +1 more source

Shrinkage of Nasal Mucosa and Cartilage during Formalin Fixation

Balkan Medical Journal, 2017
Background:After resection, specimens are subjected to formalin fixation during histologic processing. This procedure can result in tissue shrinkage, with amount of shrinkage related to tissue composition and tissue type. Aims: In this study,we aimed to
Leyla Kansu, Erdinç Aydın, Hampar Akkaya, Suat Avcı, Nalan Akalın   +4 more
doaj   +1 more source

Ortho-positronium Lifetime For Soft-tissue Classification [PDF]

Scientific Reports 14.1 (2024): 21155
The objective of this work is to showcase the ortho-positronium lifetime as a probe for soft-tissue characterization. We employed positron annihilation lifetime spectroscopy to experimentally measure the three components of the positron annihilation lifetime para-positronium (p-Ps), positron, and ortho-positronium (o-Ps) for three types of porcine, non-
arxiv   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Quality assessment of histopathological stainings on prolonged formalin fixed thrombus tissues retrieved by mechanical thrombectomy

Frontiers in Neurology, 2023
BackgroundFormalin-fixed retrieved clots from mechanical thrombectomy (MT) are now routinely studied using both conventional histopathologic techniques and immunohistochemistry (IHC).
Cem Bilgin, Daying Dai, Collin Johnson, Oana M. Mereuta, David F. Kallmes, Waleed Brinjikji, Ramanathan Kadirvel, Ramanathan Kadirvel   +7 more
doaj   +1 more source