Results 141 to 150 of about 174,743 (266)

Biofabrication of Endothelialized, Intrinsically Vascularized 3D‐Printed Recombinant Spider Silk Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold   +9 more
wiley   +1 more source

Gene Therapy for Cardiovascular Disease [PDF]

open access: yes, 2003
The last decade has seen substantial advances in the development of gene therapy strategies and vector technology for the treatment of a diverse number of diseases, with a view to translating the successes observed in animal models into the clinic ...
Baker, Andrew H.   +3 more
core   +4 more sources

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou   +11 more
wiley   +1 more source

PECULIARITIES OF THE FIBROSIS AND CIRRHOSIS MONITORING AMONG CHILDREN WITH CHRONIC LIVER DISEASES

open access: yesПедиатрическая фармакология, 2009
The researchers examined the opportunities to use determination in the serum among children with chronic liver diseases of various etiologies of the hyaluronic acid levels, collagen type IV, matrix metalloproteinase-2, tissue inhibitor of the matrix ...
A.N. Surkov   +4 more
doaj   +2 more sources

Role of tissue inhibitor of matrix metalloproteinase-1 in Iraqi patients with acute myeloid leukemia

open access: yesIraqi Journal of Hematology
BACKGROUND: Leukemia is characterized by an uncontrolled expansion or proliferation of hematopoietic cells that are unable to develop appropriately into mature blood cells.
Hassnien Samir AlHashemi   +1 more
doaj   +1 more source

Matrix Metalloproteinase-9 and Inflammation in Different Types of Multiple Sclerosis [PDF]

open access: yes, 2016
Different clinical courses of multiple sclerosis, heterogeneity of its clinical implications, different effect of immunomodulatory therapy for the same clinical forms implies various pathogenetic mechanisms of central nervous system damage at this ...
Chernenko, M. (Maksym)   +4 more
core   +2 more sources

Matrix Stiffness Governs Fibroblasts’ Regulation of Gingival Immune Homeostasis

open access: yesAdvanced Materials, EarlyView.
This study identifies a “mechano‐epigenetic” checkpoint in which matrix stiffness governs the immune responses of gingival fibroblasts. Using biomimetic hydrogels and human gingival explants, the studies revealed that restoring extracellular matrix stiffness actively suppresses inflammation via non‐canonical NF‐κB signaling and DNA methylation ...
Hardik Makkar   +5 more
wiley   +1 more source

Tissue Inhibitor of Metalloproteinase-1 Enhances Eosinophilic Airway Inflammation in Severe Asthma. [PDF]

open access: yesAllergy Asthma Immunol Res, 2023
Cao TBT   +7 more
europepmc   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

open access: yesAdvanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing   +5 more
wiley   +1 more source

Plasma Markers of Degradation of Extracellular Matrix with Intrauterine Herpes Infection

open access: yesДетские инфекции (Москва), 2016
The study of the dynamics of serum levels of matrix metalloproteinases (MMP-8, MMP-9) and tissue inhibitor (TIMP-1) in newborns with intrauterine herpes infection in the early neonatal period.
S. N. Beniova   +2 more
doaj   +1 more source

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