Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival [PDF]
Purpose: Ileal carcinoids are gut epithelial tumors originating from serotonin-containing enterochromaffin (EC) cells. Therapeutic options for effectively inhibiting the growth and spread of metastatic carcinoids are still limited.
Baur, Dorothee M. +8 more
core +2 more sources
Objective: To evaluate the expression of matrix metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitor of metalloproteinase-2 (TIMP-2) in pituitary tumors and investigate their correlation with circulating plasma proteins and cavernous sinus invasion ...
Ane Caroline Thé B Freire +10 more
doaj +1 more source
The aim of this study was to determine if the activity of tartrate-resistant acid phosphatase (TRAP) in the synovial fluid (SF) and serum can be used as a marker for diagnosing the early stages of osteoarthritis (OA).
H.B. Lee, M.R. Alam, J.W. Seol, N.S. Kim
doaj +1 more source
Neutrophil Adhesion and the Release of the Free Amino Acid Hydroxylysine
During infection or certain metabolic disorders, neutrophils can escape from blood vessels, invade and attach to other tissues. The invasion and adhesion of neutrophils is accompanied and maintained by their own secretion.
Svetlana I. Galkina +7 more
doaj +1 more source
Hyperhomocysteinemia induced by excessive methionine intake promotes rupture of cerebral aneurysms in ovariectomized rats. [PDF]
BackgroundHyperhomocysteinemia (HHcy) is associated with inflammation and a rise in the expression of matrix metalloproteinase-9 (MMP-9) in the vascular wall.
Hashimoto, Tomoki +9 more
core +2 more sources
Expression of cellular adherent and invasive molecules in recurrent ovarian endometriosis
Objective This study aimed to examine expression of cellular adhesion molecules and metalloproteinases of the extracellular matrix in ectopic endometrium for evaluating their roles in recurrence of endometriosis.
Tingting Wu +4 more
doaj +1 more source
Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]
<p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo +47 more
core +2 more sources
The potential for dietary factors to prevent or treat osteoarthritis [PDF]
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping +8 more
core +1 more source
Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis. [PDF]
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Akif A. Khawaja +8 more
core +6 more sources
Background Matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), and urokinase-type plasminogen activator (uPA) are involved in colorectal cancer invasion and metastasis.
Lim Kyu +7 more
doaj +1 more source

