Results 51 to 60 of about 94,075 (253)

Role of Oxidative Stress and Genetic Polymorphism of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in COPD

Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, 2023
Article in press withdrawn by publisher.
Poonam, Sangwan, Huma, Quasimi, Jai Gopal, Sharma, Mohammad Anwar, Habib, Mohammad Iqbal, Alam   +4 more
openaire   +2 more sources

Tissue inhibitor matrix metalloproteinase 1 and risk of type 2 diabetes in a Chinese population

BMJ Open Diabetes Research & Care, 2020
IntroductionThe non-invasive enhanced liver fibrosis (ELF) score—comprising tissue inhibitor of matrix metalloproteinases-1 (TIMP1), hyaluronic acid (HA) and amino-terminal propeptide of type III procollagen (PIIINP)—has been shown to accurately predict ...
Yeli Wang
doaj   +1 more source

Expression of MMP-2, MMP-9 and TIMP-2 in pituitary tumors and their relationship with cavernous sinus invasion

Endocrine Oncology
Objective: To evaluate the expression of matrix metalloproteinase-2 (MMP-2), MMP-9 and tissue inhibitor of metalloproteinase-2 (TIMP-2) in pituitary tumors and investigate their correlation with circulating plasma proteins and cavernous sinus invasion ...
Ane Caroline Thé B Freire, Raquel S Jallad, Rafael L Batista, Andrea Glezer, Marcio C Machado, Gilberto Ochman, Valter A Cescato, Malebranche Berardo Carneiro Cunha Neto, Fernando P Frassetto, Raphael S S de Medeiros, Ericka B Trarbach   +10 more
doaj   +1 more source

Tartrate-resistant acid phosphatase, matrix metalloproteinase-2 and tissue inhibitor metalloproteinase-2 in early stages of canine osteoarthritis

Veterinární Medicína, 2008
The aim of this study was to determine if the activity of tartrate-resistant acid phosphatase (TRAP) in the synovial fluid (SF) and serum can be used as a marker for diagnosing the early stages of osteoarthritis (OA).
H.B. Lee, M.R. Alam, J.W. Seol, N.S. Kim
doaj   +1 more source

Characterization of the functional domain of tissue inhibitor of metalloproteinases-2 (TIMP-2) [PDF]

Biochemical Journal, 1993
Analysis of the functional domain of tissue inhibitor of metallo-proteinases-2 (TIMP-2) was performed using limited proteolytic degradation with trypsin. This treatment generated a 13.5 kDa fragment which was purified and shown to consist of an uncleaved N-terminal region extending from residue 1 to residue 132.
Y A, DeClerck, T D, Yean, Y, Lee, J M, Tomich, K E, Langley   +4 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Expression of cellular adherent and invasive molecules in recurrent ovarian endometriosis

Journal of International Medical Research, 2020
Objective This study aimed to examine expression of cellular adhesion molecules and metalloproteinases of the extracellular matrix in ectopic endometrium for evaluating their roles in recurrence of endometriosis.
Tingting Wu, Rongyan Zhang, Qiaoying Jiang, Zhi Li, Ruijin Wu   +4 more
doaj   +1 more source

Neutrophil Adhesion and the Release of the Free Amino Acid Hydroxylysine

Cells, 2021
During infection or certain metabolic disorders, neutrophils can escape from blood vessels, invade and attach to other tissues. The invasion and adhesion of neutrophils is accompanied and maintained by their own secretion.
Svetlana I. Galkina, Natalia V. Fedorova, Alexander L. Ksenofontov, Marina V. Serebryakova, Ekaterina A. Golenkina, Vladimir I. Stadnichuk, Ludmila A. Baratova, Galina F. Sud’ina   +7 more
doaj   +1 more source

Interaction between tissue inhibitor of metalloproteinases-2 and progelatinase A: immunoreactivity analyses [PDF]

Biochemical Journal, 1996
By immunoreactivity analysis using monoclonal antibodies, we showed that the C-terminal domain [R415–631; R is residue] of progelatinase A [pro-matrix metalloproteinase-2 (proMMP-2); EC 3.4.24.24] affected the immunoreactivity of a one-step sandwich enzyme immunoassay (sandwich EIA) for tissue inhibitor of metalloproteinases-2 (TIMP-2) in exactly the ...
N, Fujimoto, R V, Ward, T, Shinya, K, Iwata, K, Yamashita, T, Hayakawa   +5 more
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source