Results 171 to 180 of about 122,684 (358)

Protection against periodontal destruction in diabetic condition with Sardinella longiceps fish oil: expression of matrix-metalloproteinase 8 and tissue inhibitor of metalloproteinase 1

, 2019
Dian Widya Damaiyanti, Dian Mulawarmanti, Kristanti Parisihni   +2 more
openalex   +2 more sources

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, EarlyView.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

Engineering of tissue inhibitor of metalloproteinases TIMP-1 for fine discrimination between closely related stromelysins MMP-3 and MMP-10. [PDF]

J Biol Chem, 2022
Raeeszadeh-Sarmazdeh M, Coban M, Mahajan S, Hockla A, Sankaran B, Downey GP, Radisky DC, Radisky ES.   +7 more
europepmc   +1 more source

Low Tissue Inhibitor of Metalloproteinases 3 and High Matrix Metalloproteinase 14 Levels Defines a Subpopulation of Highly Invasive Foam-Cell Macrophages [PDF]

, 2008
Jason L. Johnson, Graciela B. Sala‐Newby, Yasmin Ismail, Concepción M. Aguilera, Andrew C. Newby   +4 more
openalex   +1 more source

Living Hydrogels: Harnessing Microorganism–Material Synergy for Next‐Generation Therapeutics

Advanced Science, EarlyView.
 . ABSTRACT Microorganism‐based therapies, particularly those utilizing probiotics, have emerged as a powerful biomedical strategy owing to their inherent living functionalities. These living systems can dynamically interact with host environments and self‐regulate their activity, offering superior adaptability, prolonged functionality, and ...
Shuifang Mao, Bingyao Bai, Xingqian Ye, Yiliang Lin   +3 more
wiley   +1 more source

The prognostic and diagnostic value of tissue inhibitor of metalloproteinases gene family and potential function in gastric cancer. [PDF]

J Cancer, 2021
Li Z, Jing Q, Wu L, Chen J, Huang M, Qin Y, Wang T.   +6 more
europepmc   +1 more source

The Biology and Function of Tissue Inhibitor of Metalloproteinase 2 in the Lungs [PDF]

, 2022
Louis Costanzo, Brian Soto, Richard Meier, Patrick Geraghty   +3 more
openalex   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Role of TGFbRII in myeloid cell mediated regenerative processes and fibroplasia [PDF]

, 2012
Tissue repair and fibrosis are controlled by the interaction of different cell lineages, their soluble factors and matrix signals. Recently, macrophages have been found to be crucial for proper tissue repair.
Ranjan, Rajeev
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