Gene Expression of <i>TGF-β1</i>, Matrix Metalloproteinases, and Collagen in Keloid Patients and Their Growth Patterns in 2D and 3D Cell Cultures: An <i>In Vitro</i> Study. [PDF]
Helmer A +8 more
europepmc +1 more source
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler +4 more
wiley +1 more source
Chronic Radiation-Induced Wounds: Pathogenesis, Current Therapeutic Strategies, and Emerging Regenerative Approaches. [PDF]
Yu L +9 more
europepmc +1 more source
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu +9 more
wiley +1 more source
From sebocytes to skin engineering human sebaceous organoids within a reconstructed dermal matrix. [PDF]
Pusceddu T +8 more
europepmc +1 more source
Impact of metronidazole and amoxicillin combination on matrix metalloproteinases-1 and tissue inhibitors of matrix metalloproteinases balance in generalized aggressive periodontitis. [PDF]
Cifcibasi E +4 more
europepmc +1 more source
Microenvironment of Sarcomas Associated and Not Associated with Inoculation Sites in Domestic Cats: The Role of Metalloproteinases and Angiogenic Factors. [PDF]
Wright C +11 more
europepmc +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source
Osteoarthritis Therapeutics: From Microenvironment Understanding to Regenerative Intervention-Current Advances and Future Perspectives. [PDF]
Meng Y, Wu S, Liu Q.
europepmc +1 more source
Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu +3 more
wiley +1 more source

