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Occurrence of matrix metalloproteinases and tissue inhibitors of metalloproteinases in tuberculous pleuritis

Tuberculosis, 2001
Matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMP) have been found in high concentrations in pleural effusions. Because MMP and TIMP may play a part in the causation of the fibrosis seen in tuberculous (TB) pleuritis their occurrence was examined.Pleural effusion fluid and plasma concentrations of MMP-1, MMP-2, MMP-3 ...
G, Hoheisel   +9 more
openaire   +2 more sources

Matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase expression in human preimplantation embryos

Fertility and Sterility, 2003
To examine human embryos at various stages of preimplantation development for simultaneous expression of matrix metalloproteinases (MMPs) and tissue inhibitor of matrix metalloproteinases (TIMPs).mRNAs of specific MMPs and TIMPs were examined in single human embryos, at different stages of preimplantation development, by reverse transcription ...
Hongbo, Wang   +5 more
openaire   +2 more sources

The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers

Histopathology, 2009
Aims:  The matrix metalloproteinase (MMP)/tissue inhibitor of metalloproteinase (TIMP) system has a major role in tumour invasion and metastasis. Roles in pathways involved in early tumour development are also being identified for this system, and the aim of this study was to define the expression profile of the major MMPs and TIMPs in colorectal polyp
Jeffery, Natalie   +3 more
openaire   +3 more sources

Matrix metalloproteinase‐2 regulates the expression of tissue inhibitor of matrix metalloproteinase‐2

Clinical and Experimental Pharmacology and Physiology, 2010
Summary1. Matrix metalloproteinases (MMP) are associated with the vascular remodelling seen in atherosclerosis and aneurysm. The activation and activity of MMP‐2 are regulated by the intrinsic tissue inhibitor of MMP‐2 (TIMP‐2). The aim of the present study was to examine whether, conversely, MMP‐2 can affect the gene and protein expression of TIMP‐2.2.
Kaoru, Kimura   +9 more
openaire   +2 more sources

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

The FASEB Journal, 1991
Matrix metalloproteinases are an important group of zinc enzymes responsible for degradation of the extracellular matrix components such as collagen and proteoglycans in normal embryogenesis and remodeling and in many disease processes such as arthritis, cancer, periodontitis, and osteoporosis.
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Expression of tissue levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in gastric adenocarcinoma

Journal of Surgical Oncology, 2010
AbstractBackground and ObjectivesMatrix metalloproteinases (MMPs) are one of the major classes of proteolytic enzymes involved in tumor invasion and metastasis, being inhibited by naturally occurring tissue inhibitors of metalloproteinases (TIMPs).
Ming, Zhang   +4 more
openaire   +2 more sources

Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Sera and Tissue of Patients with Dupuytren’s Disease

Plastic and Reconstructive Surgery, 2003
Dupuytren's contracture is a fibroproliferative disorder characterized by progressive deposition of mature collagen fibers. In other fibrotic diseases affecting organs such as the liver, lung, heart, and skin, matrix metalloproteinases (MMPs) and their natural inhibitors, the tissue inhibitors of metalloproteinases (TIMPs), play an important role.
Dietmar, Ulrich   +2 more
openaire   +2 more sources

Quantification of matrix metalloproteinases and tissue inhibitors of metalloproteinase in prostatic tissue: Analytical aspects

The Prostate, 1998
The balance between matrix metalloproteinases (MMP) and the tissue inhibitors of metalloproteinases (TIMP) has been seen as important during tumor invasion and progression. The determination of these components needs a special strategy of tissue preparation.
K, Jung   +6 more
openaire   +2 more sources

[Expression of matrix metalloproteinases and tissue inhibitor of metalloproteinase in ameloblastoma].

Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2004
To study the expression of matrix metalloproteinase(MMP) and tissue inhibitor of metalloproteinase (TIMP) in ameloblastoma (AB) and to determine the relationship between biological behavior of AB and clinical pathology.The specimens of 43 cases of AB, 10 cases of odontogenic keratocyst (OKC), 8 cases of normal oral mucosa were examined by streptavidin ...
Ming, Zhong   +5 more
openaire   +1 more source

[Expression of matrix metalloproteinase and tissue inhibitor of metalloproteinase in adenomyosis].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2008
To investigate the expressions of matrix metalloproteinase -2, -3 (MMP-2,-3) and tissue inhibitor of metalloproteinase-2 (TIMP-2) in internal uterine endometriosis tissue and endometrium from women with and without endometriosis throughout the menstrual cycle.Immunohistochemical staining of tissues was performed to study the expressions and locations ...
Fang, Qiu   +6 more
openaire   +1 more source

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