Results 61 to 70 of about 2,104,548 (252)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Interferometric wavefront sensing for extreme adaptive optics [PDF]

open access: yes, 2004
Adaptive optics is concerned with the correction of phase distortions in wavefronts which degrade the quality of images produced by optical systems. It was originally developed for both astronomy and the military, where the Earth's atmosphere causes ...
Oag, Thomas J. D., Oag, Thomas J D
core  

Butterfly Optics Exceed the Theoretical Limits of Conventional Apposition Eyes [PDF]

open access: yes, 1987
Optical experiments on butterfly compound eyes show that they have angular sensitivities narrower than expected from conventional apposition eyes. This superior performance is explained by a theoretical model where the cone stalk is considered as a ...
Nilsson, D.-E.,   +3 more
core   +2 more sources

Label-free neuroimaging in vivo using synchronous angular scanning microscopy with single-scattering accumulation algorithm

open access: yesNature Communications, 2019
A major challenge of in vivo imaging is imaging deeper, including in turbid tissue. The authors report an adaptive optics based microscope that uses coherent single scattering signal to reduce sample-induced aberrations and enable fast deep-tissue ...
Moonseok Kim   +10 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Combined information from Raman spectroscopy and optical coherence tomography for enhanced diagnostic accuracy in tissue discrimination [PDF]

open access: yes, 2014
We thank the UK EPSRC for funding, the CR-UK/EPSRC/MRC/DoH (England) imaging programme, the European Union project FAMOS (FP7 ICT, contract no. 317744) and the European Union project IIIOS (FP7/2007-2013, contract no. 238802).
C. Simon Herrington   +11 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

An embedded adaptive optics real time controller [PDF]

open access: yes, 2007
The design and realisation of a low cost, high speed control system for adaptive optics (AO) is presented. This control system is built around a field programmable gate array (FPGA).
Saunter, Christopher D.   +1 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Matching optics for Gaussian beams [PDF]

open access: yes, 1991
A system of matching optics for Gaussian beams is described. The matching optics system is positioned between a light beam emitter (such as a laser) and the input optics of a second optics system whereby the output from the light beam emitter is ...
Gunter, William D.
core  

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