Results 31 to 40 of about 156,767 (359)
Orolingual angioedema is a rare, but extremely dangerous complication of systemic thrombolytic therapy with recombinant tissue plasminogen activator, the incidence of which reaches 2.2-5.1 %.
E. A. Kovaleva+6 more
doaj +1 more source
Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Cucchiara, B.+8 more
core +1 more source
At present, the only FDA approved treatment for ischemic strokes is intravenous administration of tissue plasminogen activator within 4.5 hours of stroke onset.
Philip V Peplow
doaj +1 more source
Tumor markers in breast cancer - European Group on Tumor Markers recommendations [PDF]
Recommendations are presented for the routine clinical use of serum and tissue-based markers in the diagnosis and management of patients with breast cancer.
Abraha RS+136 more
core +1 more source
PAI1 blocks NMDA receptor-mediated effects of tissue-type plasminogen activator on cell signaling and physiology [PDF]
The fibrinolysis proteinase tissue-type plasminogen activator (tPA, also known as PLAT) triggers cell signaling and regulates cell physiology. In PC12 cells, Schwann cells and macrophages, the N-methyl-D-aspartate receptor (NMDA-R) mediates tPA signaling.
Azmoon, Pardis+5 more
core +2 more sources
Tissue Plasminogen Activator in the Lens
Biochemical analyses of normal lenses from monkey, dog and calf eyes revealed significant levels of tissue plasminogen activator (t-PA). By immunohistochemistry, a positive reaction product for t-PA was seen, in descending order of staining intensity, in the central epithelium, equatorial epithelium, superficial fibers of the anterior cortex, and ...
John D. Geanon+2 more
openaire +3 more sources
Plasminogen Activator – Multifunctional Protein of Plague Pathogen
Yersinia pestis plasminogen activator, a surface protease (Pla) is encoded by species-specific plasmid pPla. This enzyme belongs to outer membrane protein family and has a ß-barrel structure.
L. M. Kukleva, A. V. Boiko
doaj +1 more source
Spectrophotometric analysis of thrombolytic activity: SATA assay [PDF]
Introduction: Measurement of thrombolytic activity i.e. clot lysis is crucial for research and development of novel thrombolytics. It is also a key factor in assessment of the effectiveness of conventionally used thrombolytic agents in the clinic, which ...
Entekhabi, Nazila+5 more
core +2 more sources
Plasminogen Activator from Porcine Heart Tissue
By ion exchange chromatography, precipitation with (NH4)2SO4 and gel filtration highly enriched tissue activator of plasminogen is prepared from pig heart tissue. Further purification can be achieved by isoelectric focusing. With the same technique five
P. Cuendet, E.E. Rickli
doaj +1 more source
Early increases in plasminogen activator activity following partial hepatectomy in humans [PDF]
Background Increases in urokinase-like plasminogen activator (uPA) activity are reported to be amongst the earliest events occurring in remnant liver following partial hepatectomy in rats, and have been proposed as a key component of the regenerative ...
Bird, N.C.+3 more
core +2 more sources