Results 31 to 40 of about 599,368 (371)

Diagnostic Ultrasound Induced Inertial Cavitation To Non-Invasively Restore Coronary And Microvascular Flow In Acute Myocardial Infarction [PDF]

open access: yes, 2013
Ultrasound induced cavitation has been explored as a method of dissolving intravascular and microvascular thrombi in acute myocardial infarction. The purpose of this study was to determine the type of cavitation required for success, and whether longer ...
Everbach, E. Carr   +11 more
core   +3 more sources

A Narrative Review on Plasminogen Activator Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target?

open access: yesInternational Journal of Molecular Sciences, 2021
Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of plasminogen activators (PAs) and is therefore an important inhibitor of the plasminogen/plasmin system.
M. Sillen, P. Declerck
semanticscholar   +1 more source

Efficacy and safety of rivaroxaban versus placebo after lower extremity bypass surgery: A post hoc analysis of a “CASPAR like” outcome from VOYAGER PAD

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1143-1146, December 2022., 2022
Abstract Background The Clopidogrel and Acetylsalicylic Acid in Bypass Surgery for Peripheral Arterial Disease (CASPAR) trial is the only large, double‐blind, placebo‐controlled trial of dual antiplatelet therapy (DAPT) versus aspirin in patients with peripheral artery disease (PAD) after lower extremity revascularization (LER).
Marc P. Bonaca   +9 more
wiley   +1 more source

The Plasminogen–Activator Plasmin System in Physiological and Pathophysiological Angiogenesis

open access: yesInternational Journal of Molecular Sciences, 2021
Angiogenesis is a process associated with the migration and proliferation of endothelial cells (EC) to form new blood vessels. It is involved in various physiological and pathophysiological conditions and is controlled by a wide range of proangiogenic ...
A. Ismail, B. Shaker, K. Bajou
semanticscholar   +1 more source

Successful Treatment of Arterial Thrombus in an Extremely Low-Birth-Weight Preterm Neonate

open access: yesPediatrics and Neonatology, 2013
Arterial thromboembolism in the pediatric population frequently occurs secondary to arterial catheterization. Catheterization-related complications are more common in smaller and sicker infants, due to high prothrombotic activity, low levels of natural ...
Petek G. Kayıran   +2 more
doaj   +1 more source

Intravenous tissue plasminogen activator for ischemic stroke in early pregnancy dosed by actual body weight

open access: yesSAGE Open Medical Case Reports, 2019
Introduction: Few published reports highlight intravenous tissue plasminogen activator use during the first trimester of pregnancy and provide outcomes for mother and fetus.
Gary D Peksa, Jamie Ostrem, Teresa Davis
doaj   +1 more source

Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis

open access: yesHaematologica, 2012
Background We recently assigned a new fibrinolytic function to cell-derived microparticles in vitro. In this study we explored the relevance of this novel property of microparticles to the in vivo situation.Design and Methods Circulating microparticles ...
Romaric Lacroix   +14 more
doaj   +1 more source

Tissue plasminogen activator for dysfunctional tunneled vascular catheters for hemodialysis - single center experience [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. Thrombosis of hemodialysis catheters is one of the major complications, which leads to catheter dysfunction. Although tissue plasminogen activator has been proven to be effective in reestablishing blood flow rate through ...
Todorov Verica   +5 more
doaj   +1 more source

Protective role of N-acetylcysteine and Sulodexide on endothelial cells exposed on patients’ serum after SARS-CoV-2 infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Severe acute respiratory syndrome coronavirus-2 causes hyperinflammation and activation of coagulation cascade and, as a result, aggravates endothelial cell dysfunction. N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage.
Justyna Rajewska-Tabor   +5 more
doaj   +1 more source

Tissue plasminogen activator-based nanothrombolysis for ischemic stroke

open access: yesExpert Opinion on Drug Delivery, 2018
Introduction: Thrombolysis with intravenous tissue plasminogen activator (tPA) is the only FDA approved treatment for patients with acute ischemic stroke, but its use is limited by narrow therapeutic window, selective efficacy, and hemorrhagic ...
Shang-ji Liu   +3 more
semanticscholar   +1 more source

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