Results 41 to 50 of about 599,368 (371)

Reversal of cilioretinal artery occlusion with intra-arterial tissue plasminogen activator

American Journal of Ophthalmology Case Reports, 2017
Purpose: To present the reversal of a cilioretinal artery occlusion with the use of intra-arterial tissue plasminogen activator. Observations: A monocular 74 year old male presented with a cilioretinal artery occlusion.
Andrew J. McClellan, Harry W. Flynn, Jr., Eric C. Peterson, Norman J. Schatz   +3 more
doaj   +1 more source

Orolingual angioedema as a complication of systemic thrombolytic therapy with recombinant tissue plasminogen activator

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
Orolingual angioedema is a rare, but extremely dangerous complication of systemic thrombolytic therapy with recombinant tissue plasminogen activator, the incidence of which reaches 2.2-5.1 %.
E. A. Kovaleva, Kh. V. Korigova, A. I. Vyshlova, E. V. Shevchenko, L. Kh.-B. Akhmatkhanova, G. R. Ramazanov, I. S. Aliev   +6 more
doaj   +1 more source

Treatment With Tissue Plasminogen Activator in the Golden Hour and the Shape of the 4.5-Hour Time-Benefit Curve in the National United States Get With The Guidelines-Stroke Population

Circulation, 2017
Background: Earlier tissue plasminogen activator treatment improves ischemic stroke outcome, but aspects of the time-benefit relationship still not well delineated are: (1) the degree of additional benefit accrued with treatment in the first 60 minutes ...
J. Kim, G. Fonarow, Eric E. Smith, M. Reeves, Digvijaya Navalkele, J. Grotta, Maria V. Grau‐Sepulveda, Adrian F. Hernandez, E. Peterson, L. Schwamm, J. Saver   +10 more
semanticscholar   +1 more source

Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis

European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023
Neutrophils play a role in the immunopathology SARS‐CoV‐2 infection by triggering the formation of NETs, producing cytokines including interleukin‐8 (CXCL8), and mediating the recruitment of other immune cells to regulate inflammation, which can lead to ARDS.
Maria Candida Cesta, Mara Zippoli, Carolina Marsiglia, Elizabeth M. Gavioli, Giada Cremonesi, Akram Khan, Flavio Mantelli, Marcello Allegretti, Robert Balk   +8 more
wiley   +1 more source

Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge.

Circulation, 1987
Intravenous administration of 80 mg of recombinant tissue plasminogen activator (rt-PA, 40, 20, and 20 mg in successive hours) and streptokinase (SK, 1.5 million units over 1 hr) was compared in a double-blind, randomized trial in 290 patients with ...
J. Chesebro, G. Knatterud, R. Roberts, J. Borer, L. Cohen, J. Dalen, H. Dodge, C. Francis, D. Hillis, P. Ludbrook   +9 more
semanticscholar   +1 more source

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Combination therapy with liposomal neuroprotectants and tissue plasminogen activator for treatment of ischemic stroke

The FASEB Journal, 2017
For ischemic stroke treatment, extension of the therapeutic time window (TTW) of thrombolytic therapy with tissue plasminogen activator (tPA) and amelioration of secondary ischemia/reperfusion (I/R) injury are most desirable.
T. Fukuta, T. Asai, Y. Yanagida, M. Namba, Hiroyuki Koide, K. Shimizu, N. Oku   +6 more
semanticscholar   +1 more source

Growth and fibrinolytic parameters of human umbilical vein endothelial cells seeded onto cardiovascular grafts [PDF]

, 1995
It was the aim of this study to investigate possible effects of biomaterials used to produce vascular grafts on the fibrinolytic system of endothelial cells.
Binder, Bernd R., Wojta, Johann, Zhang, Jing Chuan   +2 more
core   +1 more source

The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction.

New England Journal of Medicine, 1993
BACKGROUND Although it is known that thrombolytic therapy improves survival after acute myocardial infarction, it has been debated whether the speed with which coronary-artery patency is restored after the initiation of therapy further affects outcome.
Gusto Angiographic Investigators
semanticscholar   +1 more source

Neuroimmunomodulatory effects of transcranial laser therapy combined with intravenous tPA administration for acute cerebral ischemic injury

Neural Regeneration Research, 2015
At present, the only FDA approved treatment for ischemic strokes is intravenous administration of tissue plasminogen activator within 4.5 hours of stroke onset.
Philip V Peplow
doaj   +1 more source