Results 101 to 110 of about 4,698,204 (249)

Expression of lymphatic markers in the adult rat spinal cord

Frontiers in Cellular Neuroscience, 2016
Under physiological conditions, lymphatic vessels are thought to be absent from the central nervous system (CNS), although they are widely distributed within the rest of the body. Recent work in the eye, i.e.
Alexandra eKaser-Eichberger, Falk eSchroedl, Falk eSchroedl, Lara eBieler, Lara eBieler, Andrea eTrost, Barbara eBogner, Christian eRunge, Herbert eTempfer, Herbert eTempfer, Pia eZaunmair, Pia eZaunmair, Christina eKreutzer, Christina eKreutzer, Andreas eTraweger, Andreas eTraweger, Herbert Anton Reitsamer, Sebastien eCouillard-Despres, Sebastien eCouillard-Despres   +18 more
doaj   +1 more source

Stem cell–driven lymphatic remodeling coordinates tissue regeneration

Science, 2019
Stem cells reshape a lymphatic niche Adult stem cells can both self-renew and regenerate new tissue upon demand. They reside in microenvironments (niches) that balance these decisions to avoid tissue overgrowth, cancer, and aging.
S. Gur-Cohen, Hanseul Yang, Sanjeethan C. Baksh, Y. Miao, J. Levorse, Raghu P. Kataru, Xiaolei Liu, June de la Cruz-Racelis, B. Mehrara, E. Fuchs   +9 more
semanticscholar   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

Applications of Carbon Nanotubes in Bone Tissue Regeneration and Engineering: Superiority, Concerns, Current Advancements, and Prospects

Nanomaterials, 2019
With advances in bone tissue regeneration and engineering technology, various biomaterials as artificial bone substitutes have been widely developed and innovated for the treatment of bone defects or diseases.
B. Pei, Wei Wang, N. Dunne, Xiaoming Li
semanticscholar   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

Advanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim, Dai‐Hwan Kim, Priyannth R. Sundharbaabu, Chae Yeon Lee, Jina Bae, Jiyu Hyun, Young‐Ju Jang, Haeni Kim, Min‐Ho Hong, Juewen Liu, Tobias Fey, Suk Ho Bhang, Jun Hyuk Heo, Jung Heon Lee   +13 more
wiley   +1 more source

Evaluation of three obturation techniques in 3D-printed models of oval canals with standardized prepared morphology: a micro-CT study

BMC Oral Health
Background The complex and irregular morphology of prepared oval root canals poses optimal sealing in oval canals as a key endodontic challenge. To address this, this study utilized five types of standardized 3D-printed models replicating prepared ...
Wenjun Xia, Qisheng Gu, Yingshuang Song, Yunjia Liu, Xuetao Deng, Wenhao Qian   +5 more
doaj   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source