Massive resections of segments of the gastrointestinal (GI) tract lead to intestinal discontinuity. Functional tubular replacements are needed. Different scaffolds were designed for intestinal tissue engineering application.
Elie Zakhem, Khalil N. Bitar
doaj +1 more source
Pulsed vacuum arc deposition of nitrogen-doped diamond-like coatings for long-term hydrophilicity of electrospun polycaprolactone scaffolds [PDF]
The surface hydrophobicity of poly($\epsilon$-caprolactone) electrospun scaffolds prevents their interactions with cells and tissue integration. Plasma treatment of the scaffolds enhances their hydrophilicity. However, the hydrophobicity of scaffolds is restored in about 30 days.
arxiv
Fabrication and in vitro characterization of three-dimensional organic/inorganic scaffolds by robocasting [PDF]
A key issue for the fabrication of scaffolds for tissue engineering is the development of processing techniques flexible enough to produce materials with a wide spectrum of solubility (bioresorption rates) and mechanical properties matching those of calcified tissues.
arxiv +1 more source
Fabrication of Scaffolds for Bone-Tissue Regeneration
The present article describes the state of the art in the rapidly developing field of bone tissue engineering, where many disciplines, such as material science, mechanical engineering, clinical medicine and genetics, are interconnected.
Petra Chocholata, V. Kulda, V. Babuška
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Biomimicking trilayer scaffolds with controlled estradiol release for uterine tissue regeneration
Scaffold‐based tissue engineering provides an efficient approach for repairing uterine tissue defects and restoring fertility. In the current study, a novel trilayer tissue engineering scaffold with high similarity to the uterine tissue in structure was ...
Shangsi Chen+4 more
doaj +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan+10 more
wiley +1 more source
Carbon nanomaterials‐based electrically conductive scaffolds for tissue engineering applications
In tissue engineering, the pivotal role of scaffolds is underscored, serving as key elements to emulate the native extracellular matrix. These scaffolds must provide structural integrity and support and supply electrical, mechanical, and chemical cues ...
Genevieve Abd+8 more
doaj +1 more source
Simultaneous elastic shape optimization for a domain splitting in bone tissue engineering [PDF]
This paper deals with the simulateneous optimization of a subset $\mathcal{O}_0$ of some domain $\Omega$ and its complement $\mathcal{O}_1 = \Omega \setminus \overline{\mathcal{O}}_0$ both considered as separate elastic objects subject to a set of loading scenarios.
arxiv +1 more source
A preliminary study of acoustic propagation in thick foam tissue scaffolds composed of poly(lactic-co-glycolic acid) [PDF]
The exclusive ability of acoustic waves to probe the structural, mechanical and fluidic properties of foams may offer novel approaches to characterise the porous scaffolds employed in tissue engineering. Motivated by this we conduct a preliminary investigation into the acoustic properties of a typical biopolymer and the feasibility of acoustic ...
arxiv +1 more source