Results 61 to 70 of about 263,916 (334)

Ceramic identity contributes to mechanical properties and osteoblast behavior on macroporous composite scaffolds. [PDF]

, 2012
Implants formed of metals, bioceramics, or polymers may provide an alternative to autografts for treating large bone defects. However, limitations to each material motivate the examination of composites to capitalize on the beneficial aspects of ...
Genetos, Damian C, Leach, J Kent, Morales-Hernandez, Diana G, Murphy, Kaitlin C, Working, David M   +4 more
core   +4 more sources

Scaffolds for connective tissue regeneration

Biomedicine & Pharmacotherapy, 2006
In most skeletal tissue applications, an ideal scaffolds should be biocompatible and biodegradable in medium-long term; it should initially maintain its structural behaviours, allow cellular ingrowth and diffusion of nutrient, and used as carrier of growth factors and drugs.
V Guarino, A Gloria, F Causa, R De Santis, L Ambrosio   +4 more
openaire   +6 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Introduction to the Special Issue on Stem Cell and Biologic Scaffold Engineering

Bioengineering, 2019
Tissue engineering and regenerative medicine is a rapidly evolving research field that effectively combines stem cells and biologic scaffolds in order to replace damaged tissues. Biologic scaffolds can be produced through the removal of resident cellular
Panagiotis Mallis, Catherine Stavropoulos-Giokas, Efstathios Michalopoulos   +2 more
doaj   +1 more source

Multi-function based modeling of 3D heterogeneous wound scaffolds for improved wound healing [PDF]

, 2010
This paper presents a new multi-function based modeling of 3D heterogeneous porous wound scaffolds to improve wound healing process for complex deep acute or chronic wounds.
Koc, Bahattin, Koç, Bahattin, Ozbolat, Ibrahim T., Özbolat, İbrahim T.   +3 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Targeted protein delivery: carbodiimide crosslinking influences protein release from microparticles incorporated within collagen scaffolds [PDF]

, 2019
open access articleTissue engineering response may be tailored via controlled, sustained release of active agents from protein-loaded degradable microparticles incorporated directly within three-dimensional (3D) ice-templated collagen scaffolds. However,
Best, S., Cameron, Ruth, E, McCaskie, Andrew, W, Qutachi, Omar, Shakesheff, K.M., Tanase, Constantin, Edi, White, L.J.   +6 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Carbon nanomaterials‐based electrically conductive scaffolds for tissue engineering applications

MedComm – Biomaterials and Applications
In tissue engineering, the pivotal role of scaffolds is underscored, serving as key elements to emulate the native extracellular matrix. These scaffolds must provide structural integrity and support and supply electrical, mechanical, and chemical cues ...
Genevieve Abd, Raquel S. Díaz, Anju Gupta, Tagbo H. R. Niepa, Kunal Mondal, Seeram Ramakrishna, Ashutosh Sharma, Andrés D. Lantada, Monsur Islam   +8 more
doaj   +1 more source

Enhanced contrast imaging with polyamide 6/Fe(OH)3 nanofibrous scaffolds: A focus on high T1 relaxivity

Giant
Nanofibers serve as widely employed tissue engineering scaffolds in diverse biomedical applications. When implanted in vivo, it is crucial for tissue engineering scaffolds to be visualizable, enabling the monitoring of their shape, position, and ...
Congyi Yang, Yifan Jia, Weiwen Yuan, Guoxing Liao, Qianqian Yu, Zhe Tang, Yuan Ji, Guanghui Liu, Fangrong Tan, Paul D. Topham, LinGe Wang   +10 more
doaj   +1 more source