Results 91 to 100 of about 4,666,864 (263)

Thrombomodulin Expression in Bladder Cancer Tissue and Its Association with Prognosis and Patient Survival

Research and Reports in Urology, 2020
Joanne Watt, Daniel G Maguire, Cherith N Reid, John V Lamont, Stephen P Fitzgerald, Mark W Ruddock Randox Laboratories Ltd, Molecular Biology, Crumlin, County Antrim BT29 4QY, Northern Ireland, UKCorrespondence: Mark W RuddockRandox Laboratories Ltd ...
Watt J, Maguire DG, Reid CN, Lamont JV, Fitzgerald SP, Ruddock MW   +5 more
doaj  

Epidemiological study of soft‐tissue sarcomas in Ireland

Cancer Medicine, 2016
Soft‐tissue sarcomas (STS) account for 1% of adult and 7% of pediatric malignancies. Histopathology and classification of these rare tumors requires further refinements.
Nikita Bhatt, Sandra Deady, Amy Gillis, Alexia Bertuzzi, Aurelie Fabre, Eric Heffernan, Charles Gillham, Gary O'Toole, Paul F. Ridgway   +8 more
doaj   +1 more source

Modulation of growth and differentiation of mesenchymal cells for cartilage and bone tissue engineering [PDF]

, 2015
Tissue engineering is a highly promising technology for the treatment of challenging cartilage and bone lesions for which no adequate therapeutic options are available yet.
Duhr, Ralph
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Heat shock inhibits lipopolysaccharide-induced tissue factor activity in human whole blood [PDF]

, 2007
Background During gram-negative sepsis, lipopolysaccharide (LPS) induces tissue factor expression on monocytes. The resulting disseminated intravascular coagulation leads to tissue ischemia and worsens the prognosis of septic patients.
Thielmann, Matthias, Christoph Sucker, Zacharowski, Kai, Hartmann, Matthias, Kai Zacharowski, Matthias Thielmann, Sucker, Christoph, Sucker Christoph, Thielmann Matthias, Matthias Hartmann, Zacharowski Kai, Hartmann Matthias   +11 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

BCTB Fresh Tissue Samples

This BCTB tissue subcollection consists of fresh tissue samples, that is, pieces of tissue placed in liquid nitrogen for freezing.

core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Substrates for cardiovascular tissue engineering

, 2011
Cardiovascular tissue engineering aims to find solutions for the suboptimal regeneration of heart valves, arteries and myocardium by creating ‘living’ tissue replacements outside (in vitro) or inside (in situ) the human body.
Baaijens, FPT Frank, Pedron, S, Driessen - Mol, A., Bouten, C.V.C., S. Pedron, Dankers, PYW Patricia, Bouten, CVC Carlijn, Pedron, S., A. Driessen-Mol, F.P.T. Baaijens, Baaijens, F.P.T., A.M.A. Brizard, Brizard, Aurelie M A, Dankers, P.Y.W., C.V.C. Bouten, Driessen-Mol, A Anita, Bouten, C.V.C.; id_orcid, Brizard, A.M., P.Y.W. Dankers   +18 more
core   +1 more source