Results 81 to 90 of about 4,666,864 (263)

Serum microRNA-122 predicts survival in patients with liver cirrhosis [PDF]

, 2012
Background: Liver cirrhosis is associated with high morbidity and mortality. MicroRNAs (miRs) circulating in the blood are an emerging new class of biomarkers.
Stefan Zeuzem, Albrecht Piiper (22854), Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Verena Köberle (130993), Bernd Kronenberger (131004), Bernd Kronenberger, Verena Köberle, Waidmann, Oliver, Albrecht Piiper, Oliver Waidmann (130988), Piiper, Albrecht, Friederike Brunner (130998), Köberle, Verena, Brunner, Friederike, Zeuzem, Stefan, Stefan Zeuzem (22856)   +17 more
core   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Adenosine washing improves the retention rate of fat grafts under conditions of obesity [PDF]

Archives of Aesthetic Plastic Surgery
Background Fat grafting is a commonly employed aesthetic procedure for contour enhancement. However, outcome prediction is challenging due to the complex regeneration and remodeling processes involved.
Beom Jun Kim, Han Gyu Cha, Eun Soo Park, Chang Yong Choi   +3 more
doaj   +1 more source

Notoginseng Triterpenes Inhibited Autophagy in Random Flaps via the Beclin-1/VPS34/LC3 Signaling Pathway to Improve Tissue Survival. [PDF]

Front Bioeng Biotechnol, 2021
Huang Z, Luo X, Zhang Y, Ying Y, Cai X, Lu W, Zhao J, Wang Y, Lin W, Tu Y, Xiang Z, Wu Q, Yang S, Zhu S, Li X.   +14 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Cold-induced FOXO1 nuclear transport aids cold survival and tissue storage

Nature Communications
Cold-induced injuries severely limit opportunities and outcomes of hypothermic therapies and organ preservation, calling for better understanding of cold adaptation.
Xiaomei Zhang, Lihao Ge, Guanghui Jin, Yasong Liu, Qingfen Yu, Weizhao Chen, Liang Chen, Tao Dong, Kiyoharu J. Miyagishima, Juan Shen, Jinghong Yang, Guo Lv, Yan Xu, Qing Yang, Linsen Ye, Shuhong Yi, Hua Li, Qi Zhang, Guihua Chen, Wei Liu, Yang Yang, Wei Li, Jingxing Ou   +22 more
doaj   +1 more source

The secretome of stressed peripheral blood mononuclear cells increases tissue survival in a rodent epigastric flap model. [PDF]

Bioeng Transl Med, 2021
Hacker S, Mittermayr R, Traxler D, Keibl C, Resch A, Salminger S, Leiss H, Hacker P, Gabriel C, Golabi B, Pauzenberger R, Slezak P, Laggner M, Mildner M, Michlits W, Ankersmit HJ.   +15 more
europepmc   +1 more source

Variation in tissue outcome of ovine and human engineered heart valve constructs : relevance for tissue engineering

, 2012
AIM: Clinical application of tissue engineered heart valves requires precise control of the tissue culture process to predict tissue composition and mechanical properties prior to implantation, and to understand the variation in tissue outcome.
Grootzwagers, L.G.M., Driessen - Mol, A., Geemen, van, D., Riem Vis, P.W., Bouten, C.V.C., Bouten, C.V.C.; id_orcid, Soekhradj - Soechit, R.S., Baaijens, F.P.T.   +7 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source