Results 71 to 80 of about 4,666,864 (263)

Fibroblast Growth Factor 9 Inhibited Apoptosis in Random Flap via the ERK1/2-Nrf2 Pathway to Improve Tissue Survival. [PDF]

J Clin Med, 2023
Zhang D, Raza MA, Chen J, Li B, Liu W, Han T, Yan H, Jiang L.   +7 more
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Gemcitabine Plus Docetaxel, Dacarbazine, Doxorubicin Combinations, or Doxorubicin Alone as First-Line Treatment for Advanced/Metastatic Leiomyosarcoma: A Retrospective Analysis at a Sarcoma Center

Diseases
Background/Objectives: Locally advanced and metastatic leiomyosarcoma (LMS) is an aggressive cancer with limited treatment options. This single-institution, retrospective study evaluated the efficacy of first-line chemotherapy regimens in patients with ...
Ted Kim, Clara Hao, Minggui Pan, Kristen N. Ganjoo, Nam Q. Bui   +4 more
doaj   +1 more source

Biological aspects of genetic differences in piglet survival [PDF]

, 2001
The objective of this thesis was to gain insight in the biological background of differences in the direct genetic (piglet) component of piglet survival.
Leenhouwers, J.
core  

Integrated Multi-omics Survival Analysis of Gynecologic and Breast Cancers [PDF]

, 2023
openThis study utilized a multi-omics approach, incorporating gene expression, methylation, copy number variation, and mutation data, to analyze the survival of patients with Breast Carcinoma and Gynecologic Cancers (Ovarian Serous Cystadenocarcinoma ...
ZOLFAGHARI, AMIN
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Survival of Patients With Primary Cutaneous Melanoma (Stages 0-IIА and IIB-IIC), Depending on the Presence of the BRAF Mutation in the Tumor and Surgical Treatment Option

Инновационная медицина Кубани
Background: Cutaneous melanoma is an extremely aggressive disease with an unpredictable prognosis. Even among patients with similar tumor parameters and extent of surgical treatment, survival may vary.
S. A. Yаrgunin, I. V. Reshetov, Ya. N. Shoykhet, S. I. Samoylova, O. Yu. Chukhrai, S. N. Pyatakov, V. S. Yаrgunin   +6 more
doaj   +1 more source

Angiodrastic Chemokines in Colorectal Cancer: Clinicopathological Correlations

Analytical Cellular Pathology, 2018
Aim. To study the expression of angiodrastic chemokines in colorectal tumors and correlate findings with clinicopathological parameters and survival. Methods.
George Emmanouil, George Ayiomamitis, Adamantia Zizi-Sermpetzoglou, Maria Tzardi, Andrew Moursellas, Argyro Voumvouraki, Elias Kouroumalis   +6 more
doaj   +1 more source

Alginate Biomimetic Hydrogel: A Novel Matrix for the Preservation of Encapsulated Ovarian Tissue in an Animal Model [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Introduction: Ovarian tissue cryopreservation, despite its importance in fertility preservation, often causes structural damage and reduces follicle survival.
Keyvan Sobhani, Amjad Farzinpour, Christiani Amorim, Fardin Amidi   +3 more
doaj   +1 more source

Engineering calcium peroxide based oxygen generating scaffolds for tissue survival. [PDF]

Biomater Sci, 2021
Suvarnapathaki S, Nguyen MA, Goulopoulos AA, Lantigua D, Camci-Unal G.   +4 more
europepmc   +1 more source