Perfusion process with tangential flow filtration for oncolytic VSV-GP production. [PDF]
Hamusics O+7 more
europepmc +1 more source
USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang+9 more
wiley +1 more source
Long-Term Humoral Immune Response After West Nile Virus Convalescence in Horses in a Geographic Area of Multiple Orthoflavivirus Co-Circulation. [PDF]
Tolnai CH+7 more
europepmc +1 more source
Relationship between past myocardial infarction, periodontal disease and Porphyromonas gingivalis serum antibodies : a case-control study [PDF]
Czarnecka, Danuta+8 more
core +1 more source
EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen+12 more
wiley +1 more source
Mapping of the Antinuclear Autoantibodies in Sudanese patients infected with Human Immunodeficiency Virus after HAART receiving: A cross-sectional study. [PDF]
Hajhamed NM+11 more
europepmc +1 more source
On the Agglutinin Titers of Normal Human Sera. II
Tanemoto FURUHATA+5 more
openalex +2 more sources
High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti+3 more
wiley +1 more source
Increase in H5N1 vaccine antibodies confers cross-neutralization of highly pathogenic avian influenza H5N1. [PDF]
Huang X+8 more
europepmc +1 more source
Relationship of Histoplasmin Agar-Gel Bands and Complement-Fixation Titers in Histoplasmosis
Geraldine L. Wiggins, Joseph H. Schubert
openalex +1 more source