Results 231 to 240 of about 596,088 (382)

Perfusion process with tangential flow filtration for oncolytic VSV-GP production. [PDF]

open access: yesFront Bioeng Biotechnol
Hamusics O   +7 more
europepmc   +1 more source

USP8‐Governed MDA5 Homeostasis Promotes Innate Immunity and Autoimmunity

open access: yesAdvanced Science, EarlyView.
This study reveals that USP8 stabilizes MDA5 via AKT‐mediated phosphorylation (Ser718), enhancing their interaction and MDA5 deubiquitination. USP8 inactivation degrades MDA5, suppressing type I IFN and cytokine production. Pharmacological inhibition of USP8/AKT alleviates MDA5‐driven autoimmunity, demonstrating the USP8‐MDA5 axis as a therapeutic ...
Qimin Zhang   +9 more
wiley   +1 more source

Relationship between past myocardial infarction, periodontal disease and Porphyromonas gingivalis serum antibodies : a case-control study [PDF]

open access: yes, 2018
Czarnecka, Danuta   +8 more
core   +1 more source

EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways

open access: yesAdvanced Science, EarlyView.
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen   +12 more
wiley   +1 more source

Mapping of the Antinuclear Autoantibodies in Sudanese patients infected with Human Immunodeficiency Virus after HAART receiving: A cross-sectional study. [PDF]

open access: yesSci Rep
Hajhamed NM   +11 more
europepmc   +1 more source

On the Agglutinin Titers of Normal Human Sera. II

open access: bronze, 1955
Tanemoto FURUHATA   +5 more
openalex   +2 more sources

High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

open access: yesAdvanced Science, EarlyView.
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti   +3 more
wiley   +1 more source

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