Results 51 to 60 of about 656,654 (332)

Acidity of edge surface sites of montmorillonite and kaolinite [PDF]

open access: yes, 2013
Peer ...
Cheng, Jun   +5 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Insulin Initiation and Titration in Patients With Type 2 Diabetes

open access: yesDiabetes Spectrum, 2018
Insulin initiation and titration can be challenging for many primary care providers who are involved in the treatment of patients with type 2 diabetes.
J. Chun, Jodi Strong, S. Urquhart
semanticscholar   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

The sulphur and chlorine contents of grass and maize silage

open access: yesActa Agriculturae Slovenica, 2001
In seven defined samples of grass and in six samples of maize silage the contents of sulphur and chlorine were determined by two analytical procedures: both elements with X-ray fluorescence spectrometry (XRF), sulphur separately with inductively coupled ...
Marija RAJČEVIČ   +4 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

A procedure for the determination of proteolytic activity [PDF]

open access: yes, 1950
The difficulties introduced by the desire to maintain a constant pH during an enzyme-catalyzed hydrolysis of peptide-like substrates and at the same time to determine the extent of hydrolysis by an acid-base titration have been pointed out (1), but to ...
Iselin, Beat M., Niemann, Carl
core  

Potentiostatic infrared titration of 11-Mercaptoundecanoic acid monolayers [PDF]

open access: yes, 2014
Acknowledgment This work was supported by the Spanish DGICYT under grant CTQ2008-00371 and by the Junta de Andalucía under grant P07-FQM-02492.Peer ...
Andreu, Rafael   +3 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Protein sequestration generates a flexible ultrasensitive response in a genetic network

open access: yesMolecular Systems Biology, 2009
Ultrasensitive responses are crucial for cellular regulation. Protein sequestration, where an active protein is bound in an inactive complex by an inhibitor, can potentially generate ultrasensitivity. Here, in a synthetic genetic circuit in budding yeast,
Nicolas E Buchler, Frederick R Cross
doaj   +1 more source

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